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View Structure Prediction Details

Protein: HAS1
Organism: Saccharomyces cerevisiae
Length: 505 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HAS1.

Description E-value Query
Range
Subject
Range
HAS1 - ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched i...
gi|207342060 - gi|207342060|gb|EDZ69940.1| YMR290Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190408516 - gi|190408516|gb|EDV11781.1| RNA-dependent helicase [Saccharomyces cerevisiae RM11-1a]
gi|151945998 - gi|151945998|gb|EDN64230.1| helicase associated with set1 [Saccharomyces cerevisiae YJM789]
HAS1_YEAST - ATP-dependent RNA helicase HAS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HAS1 PE=...
0.0 [1..505] [1..505]
DDX3_XENLA - Putative ATP-dependent RNA helicase an3 OS=Xenopus laevis GN=an3 PE=2 SV=1
0.0 [4..427] [183..619]
gi|13514813, gi|... - gi|2580552|gb|AAC51830.1| dead box, X isoform [Homo sapiens], gi|2580550|gb|AAC51829.1| dead box, X ...
0.0 [4..426] [142..577]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3
0.0 [4..426] [142..577]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [4..427] [183..619]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..493] [68..569]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPSNKRSR DSESTEEPVV DEKSTSKQNN AAPEGEQTTC VEKFEELKLS QPTLKAIEKM  60
   61 GFTTMTSVQA RTIPPLLAGR DVLGAAKTGS GKTLAFLIPA IELLHSLKFK PRNGTGIIVI 120
  121 TPTRELALQI FGVARELMEF HSQTFGIVIG GANRRQEAEK LMKGVNMLIA TPGRLLDHLQ 180
  181 NTKGFVFKNL KALIIDEADR ILEIGFEDEM RQIIKILPNE DRQSMLFSAT QTTKVEDLAR 240
  241 ISLRPGPLFI NVVPETDNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 549.218487
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [260-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TADGLEQGYV VCDSDKRFLL LFSFLKRNQK KKIIVFLSSC NSVKYYAELL NYIDLPVLEL  60
   61 HGKQKQQKRT NTFFEFCNAE RGILICTDVA ARGLDIPAVD WIIQFDPPDD PRDYIHRVGR 120
  121 TARGTKGKGK SLMFLTPNEL GFLRYLKASK V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 549.218487
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [411-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLNEYEFPEN KIANVQSQLE KLIKSNYYLH QTAKDGYRSY LQAYASHSLK TVYQIDKLDL  60
   61 AKVAKSYGFP VPPKVNITIG ASGKTPNTKR RKTHK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle