YRC Public Data Repository - Protein Structure Prediction

Protein:	FCP1
Organism:	Saccharomyces cerevisiae
Length:	732 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FCP1.

Description	E-value	Query Range	Subject Range
gi\|151945985 - gi\|151945985\|gb\|EDN64217.1\| protein phosphatase [Saccharomyces cerevisiae YJM789] FCP1 - Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-termina... FCP1_YEAST - RNA polymerase II subunit A C-terminal domain phosphatase OS=Saccharomyces cerevisiae (strain ATCC 2...	0.0	[1..732]	[1..732]
fcp1 - CTD phosphatase Fcp1 FCP1_SCHPO - RNA polymerase II subunit A C-terminal domain phosphatase OS=Schizosaccharomyces pombe (strain 972 /...	0.0	[3..731]	[6..712]
FBpp0310097, Fcp1-PA - This gene is referred to in FlyBase by the symbol Dmel\Fcp1 (CG12252, FBgn0035026). It is a protein_...	0.0	[17..696]	[69..786]
CE28931 - WBGene00009479 locus:fcp-1 status:Partially_confirmed TR:Q95QG8 protein_id:CAC70088.1	6.0E-83	[49..415]	[6..382]
gi\|148236185, gi... - gi\|148236185\|ref\|NP_001090168.1\| CTD phosphatase [Xenopus laevis], gi\|13487713\|gb\|AAK27686.1\| CTD ph...	1.0E-80	[12..476]	[25..440]
FCP1_ENCCU - RNA polymerase II subunit A C-terminal domain phosphatase OS=Encephalitozoon cuniculi (strain GB-M1)... FCP1_ENCCU - RNA polymerase II subunit A C-terminal domain phosphatase OS=Encephalitozoon cuniculi GN=FCP1 PE=1 S...	7.0E-71	[114..606]	[2..405]
gi\|15230893, gi\|... - gi\|225194907\|gb\|ACN81954.1\| C-terminal domain phosphatase-like 5 [Arabidopsis thaliana], gi\|15230893...	6.0E-67	[92..429]	[12..318]

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Predicted Domain #1

Region A:
Residues: [1-138]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTQIRSPQG LPYPIQIDKL IPSVGSYLHE GDRLLVYKFW YLVERASDTG DDDNEHDVSP  60
   61 GGSAGSNGVS PPTKQLRESI EFFESPYEGD LISWNVDVGD EVATANQVIC EIKRPCNHDI 120
  121 VYGGLCTQCG KEVSADAF

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [139-415]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGVPLDVVGD VDLQISETEA IRTGKALKEH LRRDKKLILV VDLDQTIIHC GVDPTIAEWK  60
   61 NDPNNPNFET LRDVKSFTLD EELVLPLMYM NDDGSMLRPP PVRKCWYYVK VRPGLKEFFA 120
  121 KVAPLFEMHI YTMATRAYAL QIAKIVDPTG ELFGDRILSR DENGSLTTKS LAKLFPTDQS 180
  181 MVVVIDDRGD VWNWCPNLIK VVPYNFFVGV GDINSNFLPK QSTGMLQLGR KTRQKSQESQ 240
  241 ELLTDIMDNE KKLQEKIDKE VKRQEEKLNH QLATAEE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	9.886057
Match:	PF03031
Description:	NLI interacting factor-like phosphatase

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [416-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPANESKEEL TKKLEYSASL EVQQQNRPLA KLQKHLHDQK LLVDDDDELY YLMGTLSNIH  60
   61 KTYYDMLSQQ NEPE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [490-641]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNLMEIIPSL KQKVFQNCYF VFSGLIPLGT DIQRSDIVIW TSTFGATSTP DIDYLTTHLI  60
   61 TKNPSTYKAR LAKKFNPQIK IVHPDWIFEC LVNWKKVDEK PYTLIVDSPI SDEELQNFQT 120
  121 QLQKRQEYLE ETQEQQHMLT SQENLNLFAA GT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	12.522879
Match:	1jnxX_
Description:	Breast cancer associated protein, BRCA1
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [642-732]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SWLNNDDDED IPDTASDDDE DDDHDDESDD ENNSEGIDRK RSIEDNHDDT SQKKTKAEPS  60
   61 QDGPVQHKGE GDDNEDSDSQ LEEELMDMLD D

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits