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View Structure Prediction Details

Protein: FCP1
Organism: Saccharomyces cerevisiae
Length: 732 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FCP1.

Description E-value Query
Range
Subject
Range
gi|151945985 - gi|151945985|gb|EDN64217.1| protein phosphatase [Saccharomyces cerevisiae YJM789]
FCP1 - Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-termina...
FCP1_YEAST - RNA polymerase II subunit A C-terminal domain phosphatase OS=Saccharomyces cerevisiae (strain ATCC 2...
0.0 [1..732] [1..732]
fcp1 - CTD phosphatase Fcp1
FCP1_SCHPO - RNA polymerase II subunit A C-terminal domain phosphatase OS=Schizosaccharomyces pombe (strain 972 /...
0.0 [3..731] [6..712]
FBpp0310097, Fcp1-PA - This gene is referred to in FlyBase by the symbol Dmel\Fcp1 (CG12252, FBgn0035026). It is a protein_...
0.0 [17..696] [69..786]
CE28931 - WBGene00009479 locus:fcp-1 status:Partially_confirmed TR:Q95QG8 protein_id:CAC70088.1
6.0E-83 [49..415] [6..382]
gi|148236185, gi... - gi|148236185|ref|NP_001090168.1| CTD phosphatase [Xenopus laevis], gi|13487713|gb|AAK27686.1| CTD ph...
1.0E-80 [12..476] [25..440]
FCP1_ENCCU - RNA polymerase II subunit A C-terminal domain phosphatase OS=Encephalitozoon cuniculi (strain GB-M1)...
FCP1_ENCCU - RNA polymerase II subunit A C-terminal domain phosphatase OS=Encephalitozoon cuniculi GN=FCP1 PE=1 S...
7.0E-71 [114..606] [2..405]
gi|15230893, gi|... - gi|225194907|gb|ACN81954.1| C-terminal domain phosphatase-like 5 [Arabidopsis thaliana], gi|15230893...
6.0E-67 [92..429] [12..318]

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Predicted Domain #1
Region A:
Residues: [1-138]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTQIRSPQG LPYPIQIDKL IPSVGSYLHE GDRLLVYKFW YLVERASDTG DDDNEHDVSP  60
   61 GGSAGSNGVS PPTKQLRESI EFFESPYEGD LISWNVDVGD EVATANQVIC EIKRPCNHDI 120
  121 VYGGLCTQCG KEVSADAF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.420 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.403 d.21.1 Diaminopimelate epimerase-like

Predicted Domain #2
Region A:
Residues: [139-415]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGVPLDVVGD VDLQISETEA IRTGKALKEH LRRDKKLILV VDLDQTIIHC GVDPTIAEWK  60
   61 NDPNNPNFET LRDVKSFTLD EELVLPLMYM NDDGSMLRPP PVRKCWYYVK VRPGLKEFFA 120
  121 KVAPLFEMHI YTMATRAYAL QIAKIVDPTG ELFGDRILSR DENGSLTTKS LAKLFPTDQS 180
  181 MVVVIDDRGD VWNWCPNLIK VVPYNFFVGV GDINSNFLPK QSTGMLQLGR KTRQKSQESQ 240
  241 ELLTDIMDNE KKLQEKIDKE VKRQEEKLNH QLATAEE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 9.886057
Match: PF03031
Description: NLI interacting factor-like phosphatase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [416-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPANESKEEL TKKLEYSASL EVQQQNRPLA KLQKHLHDQK LLVDDDDELY YLMGTLSNIH  60
   61 KTYYDMLSQQ NEPE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.687 a.156.1 S13-like H2TH domain
View Download 0.558 a.144.1 PABC (PABP) domain
View Download 0.633 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.526 d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.687 a.156.1 S13-like H2TH domain
View Download 0.636 a.156.1 S13-like H2TH domain
View Download 0.633 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.558 a.144.1 PABC (PABP) domain
View Download 0.526 d.58.36 Sulfite reductase, domains 1 and 3
View Download 0.491 d.54.1 Enolase N-terminal domain-like
View Download 0.456 a.4.5 "Winged helix" DNA-binding domain
View Download 0.451 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.449 a.179.1 Replisome organizer (g39p helicase loader/inhibitor protein)
View Download 0.444 a.64.1 Saposin
View Download 0.429 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.420 a.2.3 Chaperone J-domain
View Download 0.418 f.14.1 Voltage-gated potassium channels
View Download 0.372 a.144.1 PABC (PABP) domain
View Download 0.371 a.60.2 RuvA domain 2-like
View Download 0.354 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.353 a.60.1 SAM/Pointed domain
View Download 0.351 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.351 a.4.8 Ribosomal protein S18
View Download 0.328 d.58.17 Metal-binding domain
View Download 0.323 b.34.9 Tudor/PWWP/MBT
View Download 0.312 a.3.1 Cytochrome c
View Download 0.312 a.64.1 Saposin
View Download 0.311 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.293 a.16.1 S15/NS1 RNA-binding domain
View Download 0.291 a.112.1 Description not found.
View Download 0.290 d.58.1 4Fe-4S ferredoxins
View Download 0.285 a.77.1 DEATH domain
View Download 0.283 d.48.1 RecA protein, C-terminal domain
View Download 0.280 d.201.1 SRP19
View Download 0.278 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.275 a.144.2 Ribosomal protein L20
View Download 0.273 a.39.1 EF-hand
View Download 0.271 a.17.1 p8-MTCP1
View Download 0.267 a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.266 d.52.5 Probable GTPase Der, C-terminal domain
View Download 0.264 a.50.1 Anaphylotoxins (complement system)
View Download 0.263 a.3.1 Cytochrome c
View Download 0.260 d.58.8 Viral DNA-binding domain
View Download 0.254 a.108.1 Ribosomal protein L7/12, oligomerisation (N-terminal) domain
View Download 0.250 a.156.1 S13-like H2TH domain
View Download 0.249 a.74.1 Cyclin-like
View Download 0.247 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.245 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.244 a.7.7 BAG domain
View Download 0.241 a.156.1 S13-like H2TH domain
View Download 0.238 a.60.4 DNA repair protein Rad51, N-terminal domain
View Download 0.237 b.36.1 PDZ domain-like
View Download 0.234 a.140.4 Recombination endonuclease VII, C-terminal and dimerization domains
View Download 0.230 d.54.1 Enolase N-terminal domain-like
View Download 0.229 a.24.15 FAD-dependent thiol oxidase
View Download 0.229 a.6.1 Putative DNA-binding domain
View Download 0.227 d.56.1 GroEL-intermediate domain like
View Download 0.224 d.50.1 dsRNA-binding domain-like
View Download 0.224 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.216 d.58.1 4Fe-4S ferredoxins
View Download 0.214 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.211 a.60.8 HRDC-like
View Download 0.203 a.3.1 Cytochrome c

Predicted Domain #4
Region A:
Residues: [490-641]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNLMEIIPSL KQKVFQNCYF VFSGLIPLGT DIQRSDIVIW TSTFGATSTP DIDYLTTHLI  60
   61 TKNPSTYKAR LAKKFNPQIK IVHPDWIFEC LVNWKKVDEK PYTLIVDSPI SDEELQNFQT 120
  121 QLQKRQEYLE ETQEQQHMLT SQENLNLFAA GT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 12.522879
Match: 1jnxX_
Description: Breast cancer associated protein, BRCA1
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [642-732]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SWLNNDDDED IPDTASDDDE DDDHDDESDD ENNSEGIDRK RSIEDNHDDT SQKKTKAEPS  60
   61 QDGPVQHKGE GDDNEDSDSQ LEEELMDMLD D

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.206 0.030 nucleus a.74.1 Cyclin-like
View Download 0.206 N/A N/A a.74.1 Cyclin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle