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View Structure Prediction Details

Protein: FMP42
Organism: Saccharomyces cerevisiae
Length: 504 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FMP42.

Description E-value Query
Range
Subject
Range
gi|190408447 - gi|190408447|gb|EDV11712.1| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]
FMP42_YEAST - Protein FMP42 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FMP42 PE=1 SV=1
FMP42 - Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi...
0.0 [1..504] [1..504]
gi|12847527 - gi|12847527|dbj|BAB27605.1| unnamed protein product [Mus musculus]
0.0 [8..465] [102..608]
SLC43A1 - solute carrier family 43, member 1
0.0 [8..465] [12..513]
gi|25320111 - pir||H83965 hypothetical protein BH2528 [imported] - Bacillus halodurans (strain C-125)
gi|15615091, gi|... - gi|15615091|ref|NP_243394.1| hypothetical protein BH2528 [Bacillus halodurans C-125], gi|10175148|db...
1.0E-29 [64..209] [46..190]
gi|6980007 - gi|6980007|gb|AAF34694.1|AF222906_4 Ydl054p [Candida albicans]
2.0E-28 [61..190] [62..194]

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Predicted Domain #1
Region A:
Residues: [1-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSTRTLRYA QVACACIWCL FSAGIIFGFA ALKPILISEG VYHELCDPKD GDRLLCTAQD  60
   61 LKLNFIFALS ATVTNIMALP VGKILDMYGP RVCGIIGSCL LFLASGNFIS AKHLVSLWDP 120
  121 YLVGYTLLAV AGPFVFISCF QLANSFPQRS GTVLALLTGS FDSSSALFLL YRLLYQNWFP 180
  181 TLNVSRFFTL YLIVPVFILA CQLTIMPHSS Y

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
transporter activity 3.82096685159505 bayes_pls_golite062009
transmembrane transporter activity 3.34396155292818 bayes_pls_golite062009
substrate-specific transporter activity 3.07161916881404 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.00564985710417 bayes_pls_golite062009
organic acid transmembrane transporter activity 2.05049771748124 bayes_pls_golite062009
ion transmembrane transporter activity 1.75140121218978 bayes_pls_golite062009
active transmembrane transporter activity 1.46819549608723 bayes_pls_golite062009
cation transmembrane transporter activity 1.34985844043603 bayes_pls_golite062009
binding 1.02703439347949 bayes_pls_golite062009
secondary active transmembrane transporter activity 0.869150152038001 bayes_pls_golite062009
polyol transmembrane transporter activity 0.339747214378126 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.339747214378126 bayes_pls_golite062009
symporter activity 0.327558013224678 bayes_pls_golite062009
solute:cation symporter activity 0.327558013224678 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.222664452597504 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [212-282]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTVNHIAKIA VEGLDENGRL IEGDTGSGII PDEQERQSLI AIEREEDSIP SRPQRRKSVL  60
   61 ETYVEDKLQK K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.654 a.156.1 S13-like H2TH domain
View Download 0.658 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.606 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.500 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.454 a.4.1 Homeodomain-like
View Download 0.444 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.422 a.144.1 PABC (PABP) domain
View Download 0.402 a.4.5 "Winged helix" DNA-binding domain
View Download 0.387 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.387 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.383 a.4.5 "Winged helix" DNA-binding domain
View Download 0.368 d.95.1 Glucose permease domain IIB
View Download 0.367 a.64.1 Saposin
View Download 0.360 a.39.1 EF-hand
View Download 0.336 a.5.6 Hypothetical protein MTH1615
View Download 0.336 a.144.1 PABC (PABP) domain
View Download 0.332 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.322 a.112.1 Description not found.
View Download 0.321 a.39.1 EF-hand
View Download 0.319 a.64.1 Saposin
View Download 0.314 a.4.5 "Winged helix" DNA-binding domain
View Download 0.301 a.28.1 ACP-like
View Download 0.298 a.4.5 "Winged helix" DNA-binding domain
View Download 0.295 a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.282 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.280 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.280 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.278 a.112.1 Description not found.
View Download 0.277 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.274 a.118.1 ARM repeat
View Download 0.263 a.4.5 "Winged helix" DNA-binding domain
View Download 0.257 a.144.1 PABC (PABP) domain
View Download 0.252 a.112.1 Description not found.
View Download 0.242 a.140.2 SAP domain
View Download 0.240 a.28.1 ACP-like
View Download 0.235 a.4.5 "Winged helix" DNA-binding domain
View Download 0.234 d.141.1 Ribosomal protein L6
View Download 0.233 a.5.6 Hypothetical protein MTH1615
View Download 0.225 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.218 a.64.1 Saposin
View Download 0.217 a.112.1 Description not found.
View Download 0.214 a.4.7 Ribosomal protein L11, C-terminal domain
View Download 0.212 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.207 d.50.1 dsRNA-binding domain-like
View Download 0.204 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.204 a.39.4 Hypothetical protein MTH865
View Download 0.203 a.39.1 EF-hand

Predicted Domain #3
Region A:
Residues: [283-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGIFGVLHG KSAYEQIKSP WFYLMLLFAL VAMLRINYFI ATVRTQEEYL LNDPDLALKL  60
   61 NSIFDMLLPL GGAVSIPFIG LLLDHTDTLS TLTILFTTST AIGVFGLIPN SFTWNLIGIV 120
  121 LLVVYRPFYY TVVSDYSSKV FGFDTFGTVY GLLSCICGIF NMSQNLLDKW THTTFNMNPF 180
  181 PINLTLVILT VVFSLTLTFY IRSQILPKPV NERGLSSNYQ TI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
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