YRC Public Data Repository - Protein Structure Prediction

Protein:	YMR210W
Organism:	Saccharomyces cerevisiae
Length:	449 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YMR210W.

Description	E-value	Query Range	Subject Range
YMR210W - Putative acyltransferase with similarity to Eeb1p and Eht1p, has a minor role in medium-chain fatty ... YM60_YEAST - Putative esterase YMR210W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YMR210W PE=1 S... gi\|190408436 - gi\|190408436\|gb\|EDV11701.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a]	4.0E-98	[1..449]	[1..449]
EMB8_PICGL - Embryogenesis-associated protein EMB8 OS=Picea glauca GN=EMB8 PE=2 SV=1	6.0E-58	[19..435]	[49..436]
ABHD3_MOUSE - Phospholipase ABHD3 OS=Mus musculus GN=Abhd3 PE=1 SV=1	1.0E-56	[39..414]	[65..399]
gi\|18203711 - gi\|18203711\|gb\|AAH21196.1\| Abhydrolase domain containing 3 [Homo sapiens]	4.0E-55	[39..414]	[65..399]
gi\|15240586, gi\|... - gi\|8777426\|dbj\|BAA97016.1\| unnamed protein product [Arabidopsis thaliana], gi\|15240586\|ref\|NP_199806...	3.0E-53	[38..437]	[64..425]
gi\|15162184, gi\|... - gi\|16119616\|ref\|NP_396322.1\| hypothetical protein AGR_pAT_561 [Agrobacterium tumefaciens str. C58], ...	2.0E-51	[79..414]	[6..324]

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Predicted Domain #1

Region A:
Residues: [1-119]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLKELLPNF LIVHQEVPED PIAFKSTDKR ENENKEITIP ELIDTKVPEL ADGATDTLYG  60
   61 LLVNGHLQTA YGSFRHFDNI YKVQYKRMII KYPHGGEGTV DFAVNGRSTK RRKVEKEYV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [120-449]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTSQPVFNGN LKRRYSYYSP DDPKLNSDDA KPMLIILHGL TGGSRESYVR AIVHEITTKY  60
   61 DFEACVFNAR GCCYSAITTP LLYNGGWTND IRYCVNDLRK RFPNRKFYMM GFSLGASIMT 120
  121 NYLGEESDRT KIECAISVSN PFDLYNSAYF INSTPMGSRF YSPALGHNLL RMVRNHLSTL 180
  181 EENPDFKDVI EKHLKKIRTV RQFDNLLTGP MFGYKNAEEY YKNASSYKRI PGIRTPFIAL 240
  241 HAQDDPIVGG DLPIDQIKSN PYTLLLETST GGHVGWFKDR SGRRWYAEPL CRFLKIFHDE 300
  301 ITVKGLKPDL ENVQLPDPNC EPIATTFRAN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.39794
Match:	1a8s__
Description:	Chloroperoxidase F
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.39629727416851	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.264183693934251	bayes_pls_golite062009
hydrolase activity	0.0105361402596038	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: