YRC Public Data Repository - Protein Structure Prediction

Protein:	DDR48
Organism:	Saccharomyces cerevisiae
Length:	430 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DDR48.

Description	E-value	Query Range	Subject Range
gi\|11602643 - gi\|11602643\|emb\|CAA85481.2\| adenylate cyclase hemolysin [Bordetella bronchiseptica]	3.0E-65	[2..430]	[1137..1589]
gi\|7160624 - gi\|7160624\|emb\|CAB76450.1\| bifunctional hemolysin-adenylate cyclase precursor [Bordetella parapertus...	2.0E-64	[2..430]	[1138..1590]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	5.0E-64	[2..430]	[1137..1589]
gi\|71979945 - gi\|71979945\|gb\|AAZ57194.1\| adenylate cyclase toxin [Bordetella hinzii] gi\|66820294 - gi\|66820294\|gb\|AAY57201.1\| adenylate cyclase toxin [Bordetella hinzii] CYAA_BORP1 - Bifunctional hemolysin/adenylate cyclase OS=Bordetella pertussis (strain ATCC 9797 / DSM 5571 / NCTC... CYAA_BORPE - Bifunctional hemolysin/adenylate cyclase OS=Bordetella pertussis GN=cya PE=1 SV=2 gi\|71979945, gi\|... - gi\|71979945\|gb\|AAZ57194.1\| adenylate cyclase toxin [Bordetella hinzii], gi\|66820294\|gb\|AAY57201.1\| a... CYAA_BORPE - Bifunctional hemolysin/adenylate cyclase OS=Bordetella pertussis (strain Tohama I / ATCC BAA-589 / N...	9.0E-64	[2..430]	[1138..1590]
gi\|25534902 - pir\|\|AH2515 hypothetical protein alr7304 [imported] - Nostoc sp. (strain PCC 7120) plasmid pCC7120al... gi\|17233320, gi\|... - gi\|17233320\|ref\|NP_490410.1\| hypothetical protein alr7304 [Nostoc sp. PCC 7120], gi\|17135842\|dbj\|BAB...	2.0E-61	[2..430]	[4273..4721]
gi\|11353764 - pir\|\|C81182 iron-regulated protein FrpA, probable NMB0585 [imported] - Neisseria meningitidis (strai... FRPA_NEIMB - Iron-regulated protein FrpA OS=Neisseria meningitidis serogroup B (strain MC58) GN=frpA PE=3 SV=1 FRPA_NEIMB - Iron-regulated protein frpA OS=Neisseria meningitidis serogroup B GN=frpA PE=3 SV=1	3.0E-55	[11..423]	[730..1202]
gi\|293963, gi\|420920 - pir\|\|S35027 cytotoxin RTX homolog frpC - Neisseria meningitidis, gi\|293963\|gb\|AAA99902.1\| iron-regu... FRPC_NEIMC - Iron-regulated protein FrpC OS=Neisseria meningitidis serogroup C GN=frpC PE=3 SV=1	1.0E-54	[3..423]	[1244..1729]
LKTA_ACTAC, LKTA... - Leukotoxin OS=Aggregatibacter actinomycetemcomitans GN=lktA PE=3 SV=1, Leukotoxin OS=Actinobacillus ...	5.0E-49	[40..421]	[528..918]

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Predicted Domain #1

Region A:
Residues: [1-203]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLFDKVKQF ANSNNNNNDS GNNNQGDYVT KAENMIGEDR VNQFKSKIGE DRFDKMESKV  60
   61 RQQFSNTSIN DNDSNNNDSY GSNNNDSYGS NNNDSYGSNN NDSYGSNNND SYGSNNDDSY 120
  121 GSSNKKKSSY GSNNDDSYGS SNNNDSYGSN NNDSYGSNNN DSYGSNNDDS YGSSNKNKSS 180
  181 YGSNNDDSYG SNNDDSYGSS NKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.522879
Match:	1kapP_
Description:	Metalloprotease
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [204-430]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSSYGSSNND SYGSNNDDSY GSNNNDSYGS NNDDSYGSSN KKKSSYGSNN DDSYGSSNNN  60
   61 DSYGSNNDDS YGSSNKNKSS YGSSSNDDSY GSSNNDDSYG SSNKKKSSYG SNNDDSYGSN 120
  121 NDDSYGSSNK KKSSYGSSNN DSYGSNNDDS YGSSNKKKSS YGSNNDDSYG SSNNNDSYGS 180
  181 NNDDSYGSSN RNKNSYGSSN YGSSNNDDSY GSSNRGGRNQ YGGDDDY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.522879
Match:	1kapP_
Description:	Metalloprotease
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits