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View Structure Prediction Details

Protein: RIM13
Organism: Saccharomyces cerevisiae
Length: 727 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RIM13.

Description E-value Query
Range
Subject
Range
gi|49900979 - gi|49900979|gb|AAH75862.1| CAPN1 protein [Homo sapiens]
565.0 [0..30] [506..14]
gi|73983134 - gi|73983134|ref|XP_540866.2| PREDICTED: similar to Calpain-1 catalytic subunit (Calpain-1 large subu...
559.0 [0..30] [506..14]
CAN1_BOVIN - Calpain-1 catalytic subunit OS=Bos taurus GN=CAPN1 PE=1 SV=3
557.0 [0..30] [517..14]
gi|30584031, gi|... - gi|60654057|gb|AAX29721.1| calpain 1 [synthetic construct], gi|30584031|gb|AAP36264.1| Homo sapiens ...
557.0 [0..30] [506..14]
gi|109105521, gi... - gi|109105527|ref|XP_001114068.1| PREDICTED: calpain 1, large subunit isoform 1 [Macaca mulatta], gi|...
CAN1_MACFA - Calpain-1 catalytic subunit OS=Macaca fascicularis GN=CAPN1 PE=2 SV=1
556.0 [0..30] [506..14]
gi|8132991, gi|4... - gi|8132991|gb|AAF73443.1|AF263609_1 micromolar calcium-activated neutral protease 1 isoform B; CAPN1...
556.0 [0..30] [506..14]
gi|114638508, gi... - gi|114638518|ref|XP_001168926.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes], gi|114...
556.0 [0..30] [506..14]

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Predicted Domain #1
Region A:
Residues: [1-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDWHEFNAA IKSIYCNAEG DSSSIINRLV GLAMKSEDST FIEAVLVLKE NVSKVDKQLR  60
   61 FLWLTSTINS RFYPPIPISE ASPVSWNKTE YCAPGTEELQ RRYPGRAKLQ NEEDYSGGIE 120
  121 QCRDVPDCSL VASLINLRSK NLNLPLIKQI SSTKYHVNLS FNGSNKRLVT VDISQIPTSV 180
  181 DGKQLSLKSN DISDKIGELA LLLVSKGTYS TDGSNISID

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 143.0
Match: 1kfuL
Description: Calpain large subunit, C-terminal domain (domain IV); Calpain large subunit, middle domain (domain III); Calpain large subunit, catalytic domain (domain II)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [220-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TYRLSGFLPE ITQVNSYPFE KLWKFHKSNL CLMGAGTGNR SNDMIKPLVE NHDYSIIDIT  60
   61 YDSRLVKLRD PRNSALNVEI SYEQYLKNFK QLYLNWNQEK LFKRS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 143.0
Match: 1kfuL
Description: Calpain large subunit, C-terminal domain (domain IV); Calpain large subunit, middle domain (domain III); Calpain large subunit, catalytic domain (domain II)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [325-455]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVLHFRYDTS RYNKFSIVAD KPLFHLVNNS KVTETVWLLL ESHLQDEGSQ ENRSVSFLNE  60
   61 APECIICPIE PPVECGGNHI GLQLVKLRLD AETERLLYCY STTNNNFSIH SFSVVKEICF 120
  121 QRLKDTKSLF A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 143.0
Match: 1kfuL
Description: Calpain large subunit, C-terminal domain (domain IV); Calpain large subunit, middle domain (domain III); Calpain large subunit, catalytic domain (domain II)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [456-525]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KVLFSFPYEI EGKASFDTCN FFQNPTFELE VHSEQDYQVL MDAACISTSS HDLINIQVYY  60
   61 FNDYELIKPI 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 143.0
Match: 1kfuL
Description: Calpain large subunit, C-terminal domain (domain IV); Calpain large subunit, middle domain (domain III); Calpain large subunit, catalytic domain (domain II)
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [526-595]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFDNHYQPGQ GLKQDVPILT NVKYMIVCST YGPPASTEFE LLASIRLSSS WRLISGITLR  60
   61 SVNLIYGTYP 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.522879
Match: 1df0A
Description: Calpain large subunit, C-terminal domain (domain IV); Calpain large subunit, middle domain (domain III); Calpain large subunit, catalytic domain (domain II)
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [596-727]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YHCRNRFHWK ETSDKLKIQM TLPTKKYSTN KLFIRVVPVE SSARLRMRCN IFEPESALCV  60
   61 YECQEYRTCP SGGIVIPDLE VSRTNIVVLM IERSVPISSC LPTEGQLDEL ELFVGSSQKI 120
  121 RIEKYSDDVI PK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle