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View Structure Prediction Details

Protein: NDE1
Organism: Saccharomyces cerevisiae
Length: 560 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NDE1.

Description E-value Query
Range
Subject
Range
gi|207342266 - gi|207342266|gb|EDZ70079.1| YMR145Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190408371 - gi|190408371|gb|EDV11636.1| NADH:ubiquinone oxidoreductase [Saccharomyces cerevisiae RM11-1a]
NDE1 - Mitochondrial external NADH dehydrogenase, a type II NAD(P)H:quinone oxidoreductase that catalyzes t...
gi|151945846 - gi|151945846|gb|EDN64078.1| NADH:ubiquinone oxidoreductase [Saccharomyces cerevisiae YJM789]
NDH1_YEAST - External NADH-ubiquinone oxidoreductase 1, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 20...
0.0 [1..560] [1..560]
NDH1_SCHPO - Probable NADH-ubiquinone oxidoreductase C3A11.07, mitochondrial OS=Schizosaccharomyces pombe (strain...
SPAC3A11.07 - NADH dehydrogenase
0.0 [7..559] [4..549]
gi|25284909 - pir||D83981 pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase) pdhD [imported] - Bacillus ha...
gi|10175273, gi|... - gi|15615215|ref|NP_243518.1| dihydrolipoamide dehydrogenase [Bacillus halodurans C-125], gi|10175273...
5.0E-94 [111..543] [8..435]
gi|181575 - gi|181575|gb|AAA35764.1| dihydrolipoamide dehydrogenase precursor
6.0E-94 [107..535] [36..467]
DLDH1_ARATH - Dihydrolipoyl dehydrogenase 1, mitochondrial OS=Arabidopsis thaliana GN=LPD1 PE=1 SV=2
7.0E-94 [102..536] [33..467]

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Predicted Domain #1
Region A:
Residues: [1-102]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIRQSLMKTV WANSSRFSLQ SKSGLVKYAK NRSFHAARNL LEDKKVILQK VAPTTGVVAK  60
   61 QSFFKRTGKF TLKALLYSAL AGTAYVSYSL YREANPSTQV PQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1fcdA_
Description: Flavocytochrome c sulfide dehydrogenase, FCSD, flavin-binding subunit
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [103-144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDTFPNGSKR KTLVILGSGW GSVSLLKNLD TTLYNVVVVS PR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [182-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HYYEAEAYDV DPENKTIKVK SSAKNNDYDL DLKYDYLVVG VGAQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [384-458]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APREVSKNLM TKLEEQDSRR GLLIDNKLQL LGAKGSIFAI GDCTFHPGLF PTAQVAHQEG  60
   61 EYLAQYFKKA YKIDQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 119.68867
Match: 1ebdA_
Description: Dihydrolipoamide dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [145-181]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYFLFTPLLP STPVGTIELK SIVEPVRTIA RRSHGEV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [226-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PNTFGTPGVY EYSSFLKEIS DAQEIRLKIM SSIEKAASLS PKDPERARLL SFVVVGGGPT  60
   61 GVEFAAELRD YVDQDLRKWM PELSKEIKVT LVEALPNILN MFDKYLVDYA QDLFKEEKID 120
  121 LRLKTMVKKV DATTITAKTG DGDIENIPYG VLVWATGN

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [459-466]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNWKMTHA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 119.68867
Match: 1ebdA_
Description: Dihydrolipoamide dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [467-560]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDDSEVARLK NQIVKTQSQI EDFKYNHKGA LAYIGSDKAI ADLAVGEAKY RLAGSFTFLF  60
   61 WKSAYLAMCL SFRNRVLVAM DWAKVYFLGR DSSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 119.68867
Match: 1ebdA_
Description: Dihydrolipoamide dehydrogenase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle