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View Structure Prediction Details

Protein: JLP2
Organism: Saccharomyces cerevisiae
Length: 208 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for JLP2.

Description E-value Query
Range
Subject
Range
gi|151945834 - gi|151945834|gb|EDN64066.1| dnaJ-like protein [Saccharomyces cerevisiae YJM789]
JLP2_YEAST - Protein JLP2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=JLP2 PE=1 SV=2
JLP2 - Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E....
6.0E-59 [1..208] [1..208]
ENSPTRT00000051060 - null
CCDC25 - coiled-coil domain containing 25
4.0E-58 [1..204] [1..195]
gi|7573407, gi|1... - gi|7573407|emb|CAB87710.1| putative protein [Arabidopsis thaliana], gi|23297161|gb|AAN13108.1| unkno...
5.0E-57 [1..204] [1..194]
CG4593-PA, FBpp0... - This gene is referred to in FlyBase by the symbol Dmel\CG4593 (CG4593, FBgn0029929). It is a protein...
9.0E-57 [1..205] [1..196]
gi|12854958 - gi|12854958|dbj|BAB30178.1| unnamed protein product [Mus musculus]
3.0E-54 [1..178] [1..174]
gi|215695266, gi... - gi|34909556|ref|NP_916125.1| P0046E05.9 [Oryza sativa (japonica cultivar-group)], gi|222619254|gb|EE...
3.0E-51 [1..204] [1..194]
CE22473 - status:Partially_confirmed UniProt:Q9XW03 protein_id:CAA22448.1
2.0E-49 [1..188] [1..181]

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Predicted Domain #1
Region A:
Residues: [1-145]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYFYESKPT EYSTPYQIVM GKDKFENDLL IKWSYRELNY VWFHADKYSS GHVYLKLRPN  60
   61 EKTIDDIPQE VICDCLQLCK SESIQGNKMP QCTILITPWH NLRKNRYMNP GEVSFKSLRQ 120
  121 CRKMECGARD NKILNRLAKT RVELF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.597 0.218 cytoplasm d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.624 0.171 cytoplasm c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.668 0.122 cytoplasm c.23.1 CheY-like
View Download 0.596 0.054 cytoplasm c.18.1 DNA glycosylase
View Download 0.668 N/A N/A c.23.1 CheY-like
View Download 0.624 N/A N/A c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.597 N/A N/A d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.596 N/A N/A c.18.1 DNA glycosylase
View Download 0.534 N/A N/A c.18.1 DNA glycosylase
View Download 0.534 N/A N/A c.18.1 DNA glycosylase
View Download 0.505 N/A N/A c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.439 N/A N/A a.118.8 TPR-like
View Download 0.432 N/A N/A d.110.1 Profilin (actin-binding protein)
View Download 0.420 N/A N/A b.1.10 Clathrin adaptor appendage domain
View Download 0.419 N/A N/A d.109.2 C-terminal, gelsolin-like domain of Sec23/24
View Download 0.418 N/A N/A c.23.1 CheY-like
View Download 0.409 N/A N/A c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.406 N/A N/A c.46.1 Rhodanese/Cell cycle control phosphatase
View Download 0.383 N/A N/A d.169.1 C-type lectin-like
View Download 0.374 N/A N/A d.58.34 Formiminotransferase domain of formiminotransferase-cyclodeaminase.
View Download 0.365 N/A N/A d.13.1 HIT-like
View Download 0.352 N/A N/A d.21.1 Diaminopimelate epimerase-like
View Download 0.341 N/A N/A c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.331 N/A N/A c.50.1 Macro domain-like
View Download 0.330 N/A N/A c.55.3 Ribonuclease H-like
View Download 0.322 N/A N/A c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.319 N/A N/A c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.301 N/A N/A d.58.29 Adenylyl and guanylyl cyclase catalytic domain
View Download 0.300 N/A N/A c.23.1 CheY-like
View Download 0.287 N/A N/A d.109.2 C-terminal, gelsolin-like domain of Sec23/24
View Download 0.286 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.284 N/A N/A d.109.2 C-terminal, gelsolin-like domain of Sec23/24
View Download 0.282 N/A N/A c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.281 N/A N/A b.1.18 E set domains
View Download 0.280 N/A N/A d.80.1 Tautomerase/MIF
View Download 0.278 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.276 N/A N/A c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.275 N/A N/A a.118.8 TPR-like
View Download 0.267 N/A N/A c.50.1 Macro domain-like
View Download 0.267 N/A N/A b.55.1 PH domain-like
View Download 0.263 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.262 N/A N/A d.109.1 Actin depolymerizing proteins
View Download 0.260 N/A N/A c.114.1 YchN-like
View Download 0.257 N/A N/A c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.256 N/A N/A d.13.1 HIT-like
View Download 0.255 N/A N/A d.58.29 Adenylyl and guanylyl cyclase catalytic domain
View Download 0.248 N/A N/A d.58.4 Dimeric alpha+beta barrel
View Download 0.247 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.244 N/A N/A c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.244 N/A N/A c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.239 N/A N/A d.101.1 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
View Download 0.236 N/A N/A c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.231 N/A N/A c.52.1 Restriction endonuclease-like
View Download 0.229 N/A N/A c.71.1 Dihydrofolate reductases
View Download 0.225 N/A N/A c.46.1 Rhodanese/Cell cycle control phosphatase
View Download 0.225 N/A N/A c.47.1 Thioredoxin-like
View Download 0.224 N/A N/A c.23.5 Flavoproteins
View Download 0.223 N/A N/A c.52.1 Restriction endonuclease-like
View Download 0.222 N/A N/A c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.219 N/A N/A a.141.1 Frizzled cystein-rich domain
View Download 0.219 N/A N/A d.15.5 Staphylokinase/streptokinase
View Download 0.214 N/A N/A c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.207 N/A N/A d.169.1 C-type lectin-like
View Download 0.200 N/A N/A d.74.3 RBP11-like subunits of RNA polymerase

Predicted Domain #2
Region A:
Residues: [146-208]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNVEATLNEA KKTKNGDFFV NYIESNRSNL IEEEKLRKVA KKNQKKKNKQ SKDEVTDDMQ  60
   61 LEV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.499 a.4.5 "Winged helix" DNA-binding domain
View Download 0.606 a.4.1 Homeodomain-like
View Download 0.496 a.4.5 "Winged helix" DNA-binding domain
View Download 0.400 a.4.5 "Winged helix" DNA-binding domain
View Download 0.399 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.392 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.391 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.381 a.4.5 "Winged helix" DNA-binding domain
View Download 0.379 a.4.5 "Winged helix" DNA-binding domain
View Download 0.378 a.4.5 "Winged helix" DNA-binding domain
View Download 0.362 a.4.1 Homeodomain-like
View Download 0.360 d.75.1 tRNA splicing endonuclease EdnA, N-terminal domain
View Download 0.338 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.336 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.336 a.4.1 Homeodomain-like
View Download 0.320 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.318 a.4.1 Homeodomain-like
View Download 0.311 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.307 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.302 a.4.5 "Winged helix" DNA-binding domain
View Download 0.299 a.140.4 Recombination endonuclease VII, C-terminal and dimerization domains
View Download 0.295 a.4.1 Homeodomain-like
View Download 0.292 a.4.5 "Winged helix" DNA-binding domain
View Download 0.290 a.140.1 LEM domain
View Download 0.287 a.4.10 N-terminal Zn binding domain of HIV integrase
View Download 0.270 a.64.1 Saposin
View Download 0.268 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.265 a.4.1 Homeodomain-like
View Download 0.265 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.263 a.4.5 "Winged helix" DNA-binding domain
View Download 0.256 a.4.1 Homeodomain-like
View Download 0.251 a.101.1 Uteroglobin-like
View Download 0.243 a.140.2 SAP domain
View Download 0.226 a.140.2 SAP domain
View Download 0.220 a.5.2 UBA-like
View Download 0.215 a.4.5 "Winged helix" DNA-binding domain
View Download 0.214 a.4.1 Homeodomain-like
View Download 0.211 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.209 a.4.1 Homeodomain-like
View Download 0.202 a.140.3 Rho termination factor, N-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle