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View Structure Prediction Details

Protein: MGR3
Organism: Saccharomyces cerevisiae
Length: 501 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MGR3.

Description E-value Query
Range
Subject
Range
MGR3_YEAST - Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3 OS=Saccharomyces cerevisiae (s...
MGR3 - Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondria...
0.0 [1..501] [1..501]
SPAP27G11.02 - TPR repeat protein, unknown biological role
YIO2_SCHPO - TPR repeat-containing protein P27G11.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SP...
4.0E-59 [77..235] [31..185]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLQGMRLSQ RLHKRHLFAS KILTWTTNPA HIRHLHDIRP PASNFNTQES APIPESPANS  60
   61 PTRPQMAPKP NLKKKNRSLM YSIIGVSIVG LYFWFKSNSR KQK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPLSAQKVWK EAIWQESDKM DFNYKEALRR YIEALDECDR SHVDLLSDDY TRIELKIAEM  60
   61 YEKLNMLEEA QNLYQELLSR FFEALNVPGK VDESERGEVL RKDLRIL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.06
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.6263282952649 bayes_pls_golite062009
protein binding 0.816793912043238 bayes_pls_golite062009
hydrolase activity 0.63851966218836 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.397405385912849 bayes_pls_golite062009
small conjugating protein ligase activity 0.368200928255565 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [211-351]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKSLEINKDI ESGKRKLLQH LLLAQEEILS KSPELKEFFE NRKKKLSMVK DINRDPNDDF  60
   61 KTFVSEENIK FDEQGYMILD LEKNSSAWEP FKEEFFTARD LYTAYCLSSK DIAAALSCKI 120
  121 TSVEWMVMAD MPPGQILLSQ A

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.06
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [352-501]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLGSLFYLQA EKLEADLNQL EQKKSKESNQ ELDMGTYIKA VRFVRKNRDL CLERAQKCYD  60
   61 SVIAFAKRNR KIRFHVKDQL DPSIAQSIAL STYGMGVLSL HEGVLAKAEK LFKDSITMAK 120
  121 ETEFNELLAE AEKELEKTTV LKAAKKEGLN 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 9.06
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle