YRC Public Data Repository - Protein Structure Prediction

Protein:	YMR085W
Organism:	Saccharomyces cerevisiae
Length:	432 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YMR085W.

Description	E-value	Query Range	Subject Range
GFPT1_MOUSE - Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Mus musculus GN=Gfpt1 PE=1 SV=3	0.0	[1..428]	[271..693]
gi\|5360961 - gi\|5360961\|emb\|CAB46365.1\| glucosamine--fructose-6-phosphate aminotransferase [Drosophila melanogast...	0.0	[1..428]	[268..690]
gi\|108874391, gi... - gi\|157123473\|ref\|XP_001660161.1\| glucosamine-fructose-6-phosphate aminotransferase [Aedes aegypti], ...	0.0	[1..428]	[249..671]
gi\|4503981, gi\|3... - gi\|4503981\|ref\|NP_002047.1\| glucosamine-fructose-6-phosphate aminotransferase [Homo sapiens], pir\|\|A...	0.0	[1..428]	[255..677]

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Predicted Domain #1

Region A:
Residues: [1-263]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFYLSSDCA SLARYVSKVV YLEDNDIAHI YDGELHIHCS KIGSEDFSFR TVQKLELELS  60
   61 KIKKGPYDNF MQKEIYEQCE TTKNVMRGRV DAFTNRVVLG GLENWLTELR RAKRIIMIAS 120
  121 KASFHSCLAA RPIFEELMEV PVNVELALDF VDRNCCIFRN DVCIFVSRSG ETTDTINALN 180
  181 YCIKKEAVTI GVVNCSGSSI SRFTHCGVHT NTGPEKGIAT TKSYTSQYIA LVMIALWMSE 240
  241 DLVSKIERRK EIIQALTIVP SQI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [419-432]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDLPRDSAMS APDI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	630.9897
Match:	1jxaA_
Description:	"Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [264-418]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEVLELEPLI IELCDKKLKQ HDTFLLLGRG YQFASALEGA SKMKEISYVH SESILTNELG  60
   61 HRVLAVASDN PPIIAFATKD AFSPKIASCI DQIIERKGNP IIICNKGHKI WEQDKQKGNV 120
  121 VTLEVPQTVD CLQGILNVIP LQLISYWLAI KKDIG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	630.9897
Match:	1jxaA_
Description:	"Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

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Top Sequence Alignment Hits