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View Structure Prediction Details

Protein: ADH3
Organism: Saccharomyces cerevisiae
Length: 375 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ADH3.

Description E-value Query
Range
Subject
Range
gi|151946240 - gi|151946240|gb|EDN64471.1| alcohol dehydrogenase isoenzyme III [Saccharomyces cerevisiae YJM789]
gi|190408313 - gi|190408313|gb|EDV11578.1| alcohol dehydrogenase isoenzyme III [Saccharomyces cerevisiae RM11-1a]
ADH3 - Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to ...
ADH3_YEAST - Alcohol dehydrogenase 3, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=A...
0.0 [1..375] [1..375]
gi|7248741 - gi|7248741|gb|AAF43645.1|AF218309_1 alcohol dehydrogenase isozyme 3; Adh3 [Saccharomyces kluyveri]
0.0 [1..375] [1..373]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..375] [1..375]
ADH4_KLULA - Alcohol dehydrogenase 4, mitochondrial OS=Kluyveromyces lactis GN=ADH4 PE=3 SV=2
ADH4_KLULA - Alcohol dehydrogenase 4, mitochondrial OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70...
0.0 [1..375] [1..375]

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Predicted Domain #1
Region A:
Residues: [1-180]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRTSTLFTR RVQPSLFSRN ILRLQSTAAI PKTQKGVIFY ENKGKLHYKD IPVPEPKPNE  60
   61 ILINVKYSGV CHTDLHAWHG DWPLPVKLPL VGGHEGAGVV VKLGSNVKGW KVGDLAGIKW 120
  121 LNGSCMTCEF CESGHESNCP DADLSGYTHD GSFQQFATAD AIQAAKIQQG TDLAEVAPIL 180
  181 

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [342-375]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSPIKIVGLS ELPKVYDLME KGKILGRYVV DTSK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 311.29073
Match: 1e3jA_
Description: Ketose reductase (sorbitol dehydrogenase)
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [181-341]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CAGVTVYKAL KEADLKAGDW VAISGAAGGL GSLAVQYATA MGYRVLGIDA GEEKEKLFKK  60
   61 LGGEVFIDFT KTKNMVSDIQ EATKGGPHGV INVSVSEAAI SLSTEYVRPC GTVVLVGLPA 120
  121 NAYVKSEVFS HVVKSINIKG SYVGNRADTR EALDFFSRGL I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 311.29073
Match: 1e3jA_
Description: Ketose reductase (sorbitol dehydrogenase)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle