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View Structure Prediction Details

Protein: FAR8
Organism: Saccharomyces cerevisiae
Length: 523 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FAR8.

Description E-value Query
Range
Subject
Range
FAR8_YEAST - Factor arrest protein 8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FAR8 PE=1 SV=1
FAR8 - Protein involved in recovery from cell cycle arrest in response to pheromone, in a Far1p-independent...
0.0 [1..523] [1..523]
SPBC1773.01 - striatin homolog
YGD1_SCHPO - Uncharacterized WD repeat-containing protein C1773.01 OS=Schizosaccharomyces pombe (strain 972 / ATC...
6.0E-33 [12..198] [22..262]
STRN3_RAT, STR3_RAT - Striatin-3 (Cell-cycle autoantigen SG2NA) (S/G2 antigen) (Fragment) - Rattus norvegicus (Rat), (P584...
6.0E-21 [11..71] [77..137]
STRN3_MOUSE - Striatin-3 OS=Mus musculus GN=Strn3 PE=1 SV=1
6.0E-21 [11..71] [62..122]
STRN3 - striatin, calmodulin binding protein 3
1.0E-19 [11..71] [62..122]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAINQAHVHP HYTLPGVMHY LQTEFTKNER DRITWELERS EMKARIAELE GENRDLKHQL  60
   61 NQIQSKAVSP EGEKEEKHVP DSLLQSKLAV QENVKEIIYL LKGPNTVNQL ESLNSREAGS 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [121-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELHDLEKLNV NTPKEEGSAK TNGMDILNNA LLDTKPNPKQ GPSESPSPTK VKSLFSTANK  60
   61 RENNETISKI HSELSKVDII SSYGDCMALY DADTKSLEIH QVDANLNSKL LKKISLGQDS 120
  121 DIMKFFWVST SKLLVIEKSF HLKLFSISSA SLISDVDLLQ DSEQPFSSSD IINIDFKNKW 180
  181 LLIASKNKSQ IRIWELDNIE APEDVPINIK ETYEITHDND DDDSNDSTNI LDCILGITEK 240
  241 SLILLSSNPY QLTIYDFEGK LLQKIDLKID TILSGKPEEE GYHLFLDRKT SKLLIQLSNE 300
  301 RLLVYSFDKK KVVLKEQLTP SSTLPIQLDL NDSIITVSYS NGDFEFRNLE NLKPSIDEFV 360
  361 VADINFSERK EPVVFSSNLI VDSTPVLITV NKNNEVLLHK IKI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [203-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGDCMALYDA DTKSLEIHQV DANLNSKLLK KISLGQDSDI MKFFWVSTSK LLVIEKSFHL  60
   61 KLFSISSASL ISDVDLLQDS EQPFSSSDII NIDFKNKWLL IASKNKSQIR IWELDNIEAP 120
  121 EDVPINIKET YEITHDNDDD DSNDSTNILD CILGITEKSL ILLSSNPYQL TIYDFEGKLL 180
  181 QKIDLKIDTI LSGKPEEEGY HLFLDRKTSK LLIQLSNERL LVYSFDKKKV VLKEQLTPSS 240
  241 TLPIQLDLND SIITVSYSNG DFEFRNLENL KPSIDEFVVA DINFSERKEP VVFSSNLIVD 300
  301 STPVLITVNK NNEVLLHKIK I

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 5.06
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.92860449017551 bayes_pls_golite062009
protein binding 0.637100766251496 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle