| Protein: | HMG2 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1045 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HMG2.
| Description | E-value | Query Range |
Subject Range |
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0.0 | [1..1045] | [1..1045] |
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0.0 | [179..1038] | [52..888] |
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0.0 | [179..1038] | [52..887] |
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0.0 | [179..1038] | [52..887] |
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0.0 | [179..1038] | [52..887] |
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0.0 | [179..1038] | [52..888] |
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0.0 | [175..1038] | [48..883] |
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0.0 | [77..1023] | [3..931] |
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0.0 | [7..1038] | [12..1031] |
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Region A: Residues: [1-66] |
1 11 21 31 41 51
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1 MSLPLKTIVH LVKPFACTAR FSARYPIHVI VVAVLLSAAA YLSVTQSYLN EWKLDSNQYS 60
61 TYLSIK
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| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.793 | a.65.1 | Annexin |
| View | Download | 0.770 | a.65.1 | Annexin |
| View | Download | 0.679 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.530 | a.65.1 | Annexin |
| View | Download | 0.527 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.525 | a.77.1 | DEATH domain |
| View | Download | 0.523 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.507 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.487 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.481 | a.4.1 | Homeodomain-like |
| View | Download | 0.448 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.448 | a.65.1 | Annexin |
| View | Download | 0.419 | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.417 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.416 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.416 | a.153.1 | Nuclear receptor coactivator interlocking domain |
| View | Download | 0.402 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.388 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.383 | a.2.7 | tRNA-binding arm |
| View | Download | 0.356 | a.4.1 | Homeodomain-like |
| View | Download | 0.351 | a.5.2 | UBA-like |
| View | Download | 0.347 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.338 | d.58.10 | Acylphosphatase-like |
| View | Download | 0.338 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.338 | a.74.1 | Cyclin-like |
| View | Download | 0.334 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.327 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.322 | a.77.1 | DEATH domain |
| View | Download | 0.319 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.309 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.300 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.299 | a.74.1 | Cyclin-like |
| View | Download | 0.296 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.289 | d.50.3 | PI-Pfui intein middle domain |
| View | Download | 0.289 | a.4.1 | Homeodomain-like |
| View | Download | 0.280 | a.74.1 | Cyclin-like |
| View | Download | 0.276 | a.2.7 | tRNA-binding arm |
| View | Download | 0.275 | a.44.1 | Disulphide-bond formation facilitator (DSBA), insertion domain |
| View | Download | 0.275 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.274 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.274 | a.65.1 | Annexin |
| View | Download | 0.273 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.264 | a.47.2 | t-snare proteins |
| View | Download | 0.263 | a.3.1 | Cytochrome c |
| View | Download | 0.258 | d.48.1 | RecA protein, C-terminal domain |
| View | Download | 0.255 | a.3.1 | Cytochrome c |
| View | Download | 0.249 | a.28.1 | ACP-like |
| View | Download | 0.248 | a.30.1 | ROP protein |
| View | Download | 0.244 | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.243 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.242 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.241 | a.4.1 | Homeodomain-like |
| View | Download | 0.238 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.230 | d.42.1 | POZ domain |
| View | Download | 0.230 | a.3.1 | Cytochrome c |
| View | Download | 0.229 | a.21.1 | HMG-box |
| View | Download | 0.229 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.228 | g.63.1 | Mollusk pheromone |
| View | Download | 0.225 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.225 | a.65.1 | Annexin |
| View | Download | 0.223 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.219 | a.101.1 | Uteroglobin-like |
| View | Download | 0.218 | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.218 | d.50.3 | PI-Pfui intein middle domain |
| View | Download | 0.217 | a.28.1 | ACP-like |
| View | Download | 0.215 | a.3.1 | Cytochrome c |
| View | Download | 0.211 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.207 | a.7.7 | BAG domain |
| View | Download | 0.204 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.202 | a.118.8 | TPR-like |
| View | Download | 0.201 | a.4.10 | N-terminal Zn binding domain of HIV integrase |
| View | Download | 0.201 | a.4.1 | Homeodomain-like |
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Region A: Residues: [67-533] |
1 11 21 31 41 51
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1 PDELFEKCTH YYRSPVSDTW KLLSSKEAAD IYTPFHYYLS TISFQSKDNS TTLPSLDDVI 60
61 YSVDHTRYLL SEEPKIPTEL VSENGTKWRL RNNSNFILDL HNIYRNMVKQ FSNKTSEFDQ 120
121 FDLFIILAAY LTLFYTLCCL FNDMRKIGSK FWLSFSALSN SACALYLSLY TTHSLLKKPA 180
181 SLLSLVIGLP FIVVIIGFKH KVRLAAFSLQ KFHRISIDKK ITVSNIIYEA MFQEGAYLIR 240
241 DYLFYISSFI GCAIYARHLP GLVNFCILST FMLVFDLLLS ATFYSAILSM KLEINIIHRS 300
301 TVIRQTLEED GVVPTTADII YKDETASEPH FLRSNVAIIL GKASVIGLLL LINLYVFTDK 360
361 LNATILNTVY FDSTIYSLPN FINYKDIGNL SNQVIISVLP KQYYTPLKKY HQIEDSVLLI 420
421 IDSVSNAIRD QFISKLLFFA FAVSISINVY LLNAAKIHTG YMNFQPQ
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| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
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Region A: Residues: [534-585] |
1 11 21 31 41 51
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1 SNKIDDLVVQ QKSATIEFSE TRSMPASSGL ETPVTAKDII ISEEIQNNEC VY
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.453 | d.15.7 | Immunoglobulin-binding domains |
| View | Download | 0.467 | a.5.2 | UBA-like |
| View | Download | 0.594 | d.100.1 | L9 N-domain-like |
| View | Download | 0.619 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.611 | a.5.7 | 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain |
| View | Download | 0.412 | d.15.7 | Immunoglobulin-binding domains |
| View | Download | 0.406 | d.15.7 | Immunoglobulin-binding domains |
| View | Download | 0.405 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.403 | a.138.1 | Multiheme cytochromes |
| View | Download | 0.334 | d.58.17 | Metal-binding domain |
| View | Download | 0.329 | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.273 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.263 | b.1.18 | E set domains |
| View | Download | 0.256 | d.26.1 | FKBP-like |
| View | Download | 0.227 | d.58.17 | Metal-binding domain |
| View | Download | 0.214 | d.58.5 | GlnB-like |
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Region A: Residues: [586-685] |
1 11 21 31 41 51
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1 ALSSQDEPIR PLSNLVELME KEQLKNMNNT EVSNLVVNGK LPLYSLEKKL EDTTRAVLVR 60
61 RKALSTLAES PILVSEKLPF RNYDYDRVFG ACCENVIGYM
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| Detection Method: | |
| Confidence: | 1590.0 |
| Match: | 1dq8A_ |
| Description: | NAD-binding domain of HMG-CoA reductase; Substrate-binding domain of HMG-CoA reductase |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [686-739] |
1 11 21 31 41 51
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1 PIPVGVIGPL IIDGTSYHIP MATTEGCLVA SAMRGCKAIN AGGGATTVLT KDGM
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Region B: Residues: [842-1045] |
1 11 21 31 41 51
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1 TDKKPAAINW IEGRGKSVVA EATIPGDVVK SVLKSDVSAL VELNISKNLV GSAMAGSVGG 60
61 FNAHAANLVT ALFLALGQDP AQNVESSNCI TLMKEVDGDL RISVSMPSIE VGTIGGGTVL 120
121 EPQGAMLDLL GVRGPHPTEP GANARQLARI IACAVLAGEL SLCSALAAGH LVQSHMTHNR 180
181 KTNKANELPQ PSNKGPPCKT SALL
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| Detection Method: | |
| Confidence: | 1590.0 |
| Match: | 1dq8A_ |
| Description: | NAD-binding domain of HMG-CoA reductase; Substrate-binding domain of HMG-CoA reductase |
| Matching Structure (courtesy of the PDB): |
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Region A: Residues: [740-841] |
1 11 21 31 41 51
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1 TRGPVVRFPT LIRSGACKIW LDSEEGQNSI KKAFNSTSRF ARLQHIQTCL AGDLLFMRFR 60
61 TTTGDAMGMN MISKGVEYSL KQMVEEYGWE DMEVVSVSGN YC
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| Detection Method: | |
| Confidence: | 1590.0 |
| Match: | 1dq8A_ |
| Description: | NAD-binding domain of HMG-CoA reductase; Substrate-binding domain of HMG-CoA reductase |
| Matching Structure (courtesy of the PDB): |
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