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View Structure Prediction Details

Protein: CRN1
Organism: Saccharomyces cerevisiae
Length: 651 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CRN1.

Description E-value Query
Range		 Subject
Range
CORO_YEAST - Coronin-like protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CRN1 PE=1 SV=1
CRN1 - Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regul...
 0.0 [1..651] [1..651]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
 0.0 [3..504] [919..1430]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
 0.0 [2..508] [843..1317]

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Predicted Domain #1
Region A:
Residues: [1-70] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGKFVRASK YRHVFGQAAK KELQYEKLKV TNNAWDSNLL KTNGKFIAVN WNASGGGAFA  60
   61 VIPIEEVGKA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.743 g.18.1 Complement control module/SCR domain
View Download 0.729 d.1.1 Microbial ribonucleases
View Download 0.723 d.40.1 CI-2 family of serine protease inhibitors
View Download 0.765 d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.685 d.17.5 Uracil-DNA glycosylase inhibitor protein
View Download 0.665 b.3.2 Carboxypeptidase D, a regulatory domain
View Download 0.605 d.237.1 Hypothetical protein YjiA, C-terminal domain
View Download 0.588 d.129.1 TATA-box binding protein-like
View Download 0.556 d.93.1 SH2 domain
View Download 0.543 g.41.3 Zinc beta-ribbon
View Download 0.518 b.1.1 Immunoglobulin
View Download 0.516 b.114.1 N-utilization substance G protein NusG, insert domain
View Download 0.481 b.84.1 Single hybrid motif
View Download 0.479 d.121.1 DNA topoisomerase I domain
View Download 0.440 b.101.1 Ribonuclease domain of colicin E3
View Download 0.438 g.18.1 Complement control module/SCR domain
View Download 0.432 d.17.3 Disulfide bond isomerase, DsbC, N-terminal domain
View Download 0.431 d.129.1 TATA-box binding protein-like
View Download 0.421 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.415 b.1.14 Invasin/intimin cell-adhesion fragments
View Download 0.412 d.58.7 RNA-binding domain, RBD
View Download 0.404 g.5.1 Midkine
View Download 0.399 d.68.7 R3H domain
View Download 0.388 g.41.3 Zinc beta-ribbon
View Download 0.374 d.58.4 Dimeric alpha+beta barrel
View Download 0.353 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.345 d.110.1 Profilin (actin-binding protein)
View Download 0.339 d.17.1 Cystatin/monellin
View Download 0.337 d.129.1 TATA-box binding protein-like
View Download 0.337 d.58.7 RNA-binding domain, RBD
View Download 0.336 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.326 d.17.2 Copper amine oxidase, domains 1 and 2
View Download 0.324 d.93.1 SH2 domain
View Download 0.321 d.102.1 Regulatory factor Nef
View Download 0.320 d.58.10 Acylphosphatase-like
View Download 0.317 b.1.1 Immunoglobulin
View Download 0.304 g.27.1 Fibronectin type I module
View Download 0.298 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View Download 0.287 b.61.4 Quinohemoprotein amine dehydrogenase A chain, domain 3
View Download 0.266 d.28.1 Ribosomal protein S19
View Download 0.248 b.1.1 Immunoglobulin
View Download 0.240 b.55.1 PH domain-like
View Download 0.238 d.129.1 TATA-box binding protein-like
View Download 0.228 d.17.6 Archaeosine tRNA-guanine transglycosylase, C2 domain
View Download 0.226 c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.225 b.61.4 Quinohemoprotein amine dehydrogenase A chain, domain 3
View Download 0.216 d.225.1 Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains
View Download 0.213 b.7.2 Periplasmic chaperone C-domain
View Download 0.210 d.169.1 C-type lectin-like
View Download 0.208 b.1.1 Immunoglobulin
View Download 0.207 d.87.1 FAD/NAD-linked reductases, dimerisation (C-terminal) domain

Predicted Domain #2
Region A:
Residues: [71-390] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDQVPLFRGH TAQVLDTDFD PFNDHRIASG SDDSKIGIWD IPENYKFHDH VDEDGEPIDI  60
   61 KPVKFLTGHA RKVGHVLYHP VAENVLASSS GDYTVKLWNV ETGKDMITLK HPDMVTSMSF 120
  121 SYDGNYLATV ARDKKLRVWN IREEKIVSEG PAHTGAKNQR VVWLGNSDRL ATTGFSKLSD 180
  181 RQIGIWDAFN IEKGDLGGFY TVDQSSGILM PFYDEGNKIL YLVGKGDGNI RYYEFQNDEL 240
  241 FELSEFQSTE AQRGFAVAPK RMVNVKENEV LKGFKTVVDQ RIEPVSFFVP RRSEEFQEDI 300
  301 YPDAPSNKPA LTAEEWFSGK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 175.28043
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [391-466] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVEGPILVSM RSIYDGSAPS FHEAKRPQQP TTQETALEEK KEQPKVEKPI SESEKEVKQE  60
   61 APKSPSPLKS ASSSST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 1gxrA_
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [467-651] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INHVLKEDNS INKLLKKSSD IDQVNNAEDP SRDTSGWEEA DDEPAPIKIE TPVTPTETKK  60
   61 DRTPKVEPSK ELKPEPVSIA TDRKQEQSLP QEEKSSEKTK SPEQEKSATP PSSITAAKTA 120
  121 ITASSKEEPS AARTSPKSLG LKKSVEKLST LVLQLEDVVD KLTKANLDKD ERLLKLEQKI 180
  181 GELSK

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 12.79
Match: 1k83A
Description: RBP1
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle