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View Structure Prediction Details

Protein: CDC73
Organism: Saccharomyces cerevisiae
Length: 393 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC73.

Description E-value Query
Range
Subject
Range
CDC73_ARATH - Protein CDC73 homolog OS=Arabidopsis thaliana GN=CDC73 PE=1 SV=1
448.0 [0..30] [392..15]
gi|25334124, gi|... - gi|3859701|emb|CAA21976.1| unknown conserved hypothetical protein [Candida albicans], pir||T52156 hy...
gi|46443118, gi|... - gi|68469389|ref|XP_721209.1| potential RNA Pol II elongation accessory factor [Candida albicans SC53...
444.0 [0..20] [392..23]
gi|50290939, gi|... - gi|50290939|ref|XP_447902.1| unnamed protein product [Candida glabrata], gi|49527213|emb|CAG60851.1|...
gi|49527213 - gi|49527213|emb|CAG60851.1| unnamed protein product [Candida glabrata]
392.0 [0..5] [393..4]
CDC73_SCHPO - Cell division control protein 73 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=cdc73 PE=...
SPBC17G9.02c - RNA polymerase II accessory factor, Cdc73 family
373.0 [0..27] [390..22]
gi|49642337 - gi|49642337|emb|CAH00299.1| KLLA0D03036p [Kluyveromyces lactis]
gi|49642337, gi|... - gi|50306459|ref|XP_453203.1| unnamed protein product [Kluyveromyces lactis], gi|49642337|emb|CAH0029...
349.0 [0..5] [392..3]
gi|44983680 - gi|44983680|gb|AAS52779.1| AER095Wp [Ashbya gossypii ATCC 10895]
gi|45190701, gi|... - gi|45190701|ref|NP_984955.1| AER095Wp [Ashbya gossypii ATCC 10895], gi|44983680|gb|AAS52779.1| AER09...
338.0 [0..5] [392..3]
gi|50420559, gi|... - gi|50420559|ref|XP_458816.1| hypothetical protein DEHA0D08954g [Debaryomyces hansenii CBS767], gi|49...
gi|49654483|emb|... - unnamed protein product [Debaryomyces hansenii CBS767]
329.0 [0..5] [392..7]
gi|50543170, gi|... - gi|50543170|ref|XP_499751.1| YALI0A04345p [Yarrowia lipolytica], gi|49645616|emb|CAG83675.1| YALI0A0...
gi|49645616 - gi|49645616|emb|CAG83675.1| YALI0A04345p [Yarrowia lipolytica]
277.0 [0..3] [393..2]
CDC73_RAT - Parafibromin OS=Rattus norvegicus GN=Cdc73 PE=2 SV=1
253.0 [0..178] [388..277]
gi|109019026 - gi|109019026|ref|XP_001112553.1| PREDICTED: similar to hyperparathyroidism 2 homolog isoform 2 [Maca...
gi|125630647, gi... - gi|87042750|gb|ABD16382.1| hyperparathyroidism 2 with jaw tumor protein [Canis familiaris], gi|74005...
CDC73_MOUSE - Parafibromin OS=Mus musculus GN=Cdc73 PE=1 SV=1
CDC73 - cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
gi|114568508 - gi|114568508|ref|XP_001167188.1| PREDICTED: hypothetical protein LOC745351 isoform 2 [Pan troglodyte...
tr|F2Z3T0|F2Z3T0_RAT - Uncharacterized protein OS=Rattus norvegicus GN=Cdc73 PE=4 SV=1
tr|M3VUK6|M3VUK6... - Cell division cycle 73 OS=Felis catus GN=CDC73 PE=4 SV=1
gi|194673899 - gi|194673899|ref|XP_001787504.1| PREDICTED: similar to Vcell division cycle 73, Paf1/RNA polymerase ...
gi|190691061, gi... - gi|190691061|gb|ACE87305.1| cell division cycle 73, Paf1/RNA polymerase II complex component, homolo...
tr|G1TBE7|G1TBE7... - pep:novel chromosome:oryCun2:16:77557694:77687734:-1 gene:ENSOCUG00000016332 transcript:ENSOCUT00000...
252.0 [0..178] [388..277]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANSLDRLRE HLKNGDKLVL KNNEGQSTDD ITKATMVETL SSDGSTQDSF PLNEETEIEI  60
   61 DGSLVQLRII VHCWMNKDSS AADYLADCQN KQLTNVSFLQ RTDLINWLSG NTESSQYLKA 120
  121 PGQKGETSDK VDI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [134-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENKTLAGELS TVKSTTSASL ENDSEVSDPV VVETMKHERI LVDHNSALRG AKPINFGYLI  60
   61 KDAELKLVQS IKGSLRGSKL PPGHKGAHGR ISKTNGSSGG PRKDPIILIP SAASSILTVA 120
  121 NIKQFLLESK YVNPRNLPSV PNGLVNIEKN FERISRPIRF IIVDNTRMFT KPEYWDRVVA 180
  181 IFTTGHTWQF NNYQWNSPQE LFQRCKGYYF HFAGDSVPQH VQQWNVEKVE LDKNKRFKDV 240
  241 EVVRYFWHSL EKELISRGYR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle