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View Structure Prediction Details

Protein: CTF3
Organism: Saccharomyces cerevisiae
Length: 733 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CTF3.

Description E-value Query
Range
Subject
Range
CTF3 - Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to s...
CTF3_YEAST - Central kinetochore subunit CTF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CTF3 PE...
0.0 [1..733] [1..733]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-99 [557..733] [1..177]

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Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLILDDIIL SLTNANERTP PQALKTTLSL LYEKSKQYGL SSPQLQALVR LLCETSIIDT  60
   61 VTKVYIVENC FLPDGYLTKE LLLEIINHLG TPTVFSRYRI QTPPVLQSAL CKWLVHVYFL 120
  121 FPVHSEREHN ISSSIWLHLW QFSFLQKWIT PLVIWQATTP VDVKPWKLSI IKRCAMHP

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.1
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [179-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYRDAPGSAT LILQRFQCLV GASSQITESI ITINCNRKTL KSHRNLKLDA HFLSILKRIL  60
   61 SRAHPANFPA DTV

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.1
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [252-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNTIDMYLSE IHQLGADSIY PLRLQSLPEY VPSDSTVSLW DVTSLEQLAQ NWPQLHIPND  60
   61 VDYMMKPSLN SNVLLPRKVM SRDSLKHLYS SIILIKNSRD ESSSPYEWCI WQLKRCFAHQ 120
  121 IETPQEVIP

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.1
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [381-598]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIISVSSMDN KLSSRIIQTF CNLKYLKLDE LTLKKVCGGI LPLWKPELIS GTREFFVKFM  60
   61 ASIFMWSTRD GHDNNCTFSE TCFYVLQMIT NWVLDDKLIA LGLTLLHDMQ SLLTLDKIFN 120
  121 NATSNRFSTM AFISSLDILT QLSKQTKSDY AIQYLIVGPD IMNKVFSSDD PLLLSAACRY 180
  181 LVATKNKLMQ YPSTNKFVRM QNQYIMDLTN YLYRNKVL

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.1
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [599-733]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKSLFGVSP DFFKQILENL YIPTADFKNA KFFTITGIPA LSYICIIILR RLETAENTKI  60
   61 KFTSGIINEE TFNNFFRVHH DEIGQHGWIK GVNNIHDLRV KILMHLSNTA NPYRDIAAFL 120
  121 FTYLKSLSKY SVQNS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle