YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: CTF3
Organism: Saccharomyces cerevisiae
Length: 733 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CTF3.

Description E-value Query
Range
Subject
Range
CTF3 - Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to s...
CTF3_YEAST - Central kinetochore subunit CTF3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CTF3 PE...
0.0 [1..733] [1..733]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-99 [557..733] [1..177]

Back

Predicted Domain #1
Region A:
Residues: [1-178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLILDDIIL SLTNANERTP PQALKTTLSL LYEKSKQYGL SSPQLQALVR LLCETSIIDT  60
   61 VTKVYIVENC FLPDGYLTKE LLLEIINHLG TPTVFSRYRI QTPPVLQSAL CKWLVHVYFL 120
  121 FPVHSEREHN ISSSIWLHLW QFSFLQKWIT PLVIWQATTP VDVKPWKLSI IKRCAMHP

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.1
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [179-251]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GYRDAPGSAT LILQRFQCLV GASSQITESI ITINCNRKTL KSHRNLKLDA HFLSILKRIL  60
   61 SRAHPANFPA DTV

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.1
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [252-380]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNTIDMYLSE IHQLGADSIY PLRLQSLPEY VPSDSTVSLW DVTSLEQLAQ NWPQLHIPND  60
   61 VDYMMKPSLN SNVLLPRKVM SRDSLKHLYS SIILIKNSRD ESSSPYEWCI WQLKRCFAHQ 120
  121 IETPQEVIP

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.1
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [381-598]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIISVSSMDN KLSSRIIQTF CNLKYLKLDE LTLKKVCGGI LPLWKPELIS GTREFFVKFM  60
   61 ASIFMWSTRD GHDNNCTFSE TCFYVLQMIT NWVLDDKLIA LGLTLLHDMQ SLLTLDKIFN 120
  121 NATSNRFSTM AFISSLDILT QLSKQTKSDY AIQYLIVGPD IMNKVFSSDD PLLLSAACRY 180
  181 LVATKNKLMQ YPSTNKFVRM QNQYIMDLTN YLYRNKVL

[Run NCBI BLAST on this sequence.]

Detection Method: Pcons
Confidence: 2.1
Match: 1b3uA
Description: Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [599-733]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSKSLFGVSP DFFKQILENL YIPTADFKNA KFFTITGIPA LSYICIIILR RLETAENTKI  60
   61 KFTSGIINEE TFNNFFRVHH DEIGQHGWIK GVNNIHDLRV KILMHLSNTA NPYRDIAAFL 120
  121 FTYLKSLSKY SVQNS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.784 a.1.1 Globin-like
View Download 0.667 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.625 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.576 a.1.1 Globin-like
View Download 0.536 a.24.4 Hemerythrin
View Download 0.521 a.22.1 Histone-fold
View Download 0.485 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.483 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.439 a.1.1 Globin-like
View Download 0.438 a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.412 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.395 d.92.2 beta-N-acetylhexosaminidase-like domain
View Download 0.391 a.24.2 Aspartate receptor, ligand-binding domain
View Download 0.391 a.24.3 Cytochromes
View Download 0.378 c.25.1 Ferredoxin reductase-like, C-terminal NADP-linked domain
View Download 0.365 d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.356 c.10.2 L domain-like
View Download 0.350 a.74.1 Cyclin-like
View Download 0.348 d.95.2 Homing endonucleases
View Download 0.341 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.334 d.2.1 Lysozyme-like
View Download 0.325 a.95.1 Influenza virus matrix protein M1
View Download 0.325 d.92.2 beta-N-acetylhexosaminidase-like domain
View Download 0.321 a.26.1 4-helical cytokines
View Download 0.318 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.311 d.218.1 Nucleotidyltransferase
View Download 0.311 c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.305 a.26.1 4-helical cytokines
View Download 0.302 c.3.1 FAD/NAD(P)-binding domain
View Download 0.301 a.24.14 FAT domain of focal adhesion kinase
View Download 0.294 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.292 a.26.1 4-helical cytokines
View Download 0.291 a.1.1 Globin-like
View Download 0.290 a.25.1 Ferritin-like
View Download 0.272 c.95.1 Thiolase-like
View Download 0.264 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.260 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.254 a.116.1 GTPase activation domain, GAP
View Download 0.241 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.232 c.55.3 Ribonuclease H-like
View Download 0.230 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.225 a.61.1 Retroviral matrix proteins
View Download 0.224 a.21.1 HMG-box
View Download 0.220 a.26.1 4-helical cytokines
View Download 0.217 c.84.1 Phosphoglucomutase, first 3 domains
View Download 0.217 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.216 d.109.1 Actin depolymerizing proteins
View Download 0.211 f.1.1 Colicin
View Download 0.206 d.163.1 DNA breaking-rejoining enzymes
View Download 0.204 c.78.1 Aspartate/ornithine carbamoyltransferase
View Download 0.202 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.201 a.118.1 ARM repeat


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle