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View Structure Prediction Details

Protein: FBP1
Organism: Saccharomyces cerevisiae
Length: 348 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBP1.

Description E-value Query
Range		 Subject
Range
F16P_YEAST - Fructose-1,6-bisphosphatase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FBP1 PE=1 SV...
gi|151940899 - gi|151940899|gb|EDN59281.1| fructose-1,6-bisphosphatase [Saccharomyces cerevisiae YJM789]
FBP1 - Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for gluc...
gi|207342767 - gi|207342767|gb|EDZ70427.1| YLR377Cp-like protein [Saccharomyces cerevisiae AWRI1631]
 0.0 [1..348] [1..348]
F16P2_ORYCO - Fructose-1,6-bisphosphatase, cytosolic OS=Oryza coarctata PE=2 SV=1
 0.0 [13..345] [5..335]
F16P2_ORYSJ - Fructose-1,6-bisphosphatase, cytosolic OS=Oryza sativa subsp. japonica GN=Os01g0866400 PE=2 SV=2
F16Q_ORYSA, F16P... - (O64421) Fructose-1,6-bisphosphatase, cytosolic (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phospho...
F16P2_ORYSI - Fructose-1,6-bisphosphatase, cytosolic OS=Oryza sativa subsp. indica GN=OsI_04558 PE=2 SV=2
 0.0 [13..345] [5..335]
F16P2_ARATH - Fructose-1,6-bisphosphatase, cytosolic OS=Arabidopsis thaliana GN=At1g43670 PE=2 SV=1
 0.0 [12..348] [4..338]
F16P2_SOLTU - Fructose-1,6-bisphosphatase, cytosolic OS=Solanum tuberosum PE=2 SV=1
 0.0 [12..348] [4..338]
F16P2_BETVU - Fructose-1,6-bisphosphatase, cytosolic OS=Beta vulgaris PE=2 SV=2
 0.0 [12..348] [4..338]
gi|5305145 - gi|5305145|emb|CAB46084.1| fructose-1,6-bisphosphatase [Pisum sativum]
 0.0 [21..348] [1..326]
F16P2_MUSAC - Fructose-1,6-bisphosphatase, cytosolic OS=Musa acuminata GN=FBPban1 PE=2 SV=1
 0.0 [13..348] [5..338]
F16P_RABIT, F16P... - (P00637) Fructose-1,6-bisphosphatase (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase) ...
 0.0 [16..347] [6..334]
F16P2_SPIOL - Fructose-1,6-bisphosphatase, cytosolic OS=Spinacia oleracea PE=1 SV=2
 0.0 [12..348] [4..338]

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Predicted Domain #1
Region A:
Residues: [1-209] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTLVNGPRR DSTEGFDTDI ITLPRFIIEH QKQFKNATGD FTLVLNALQF AFKFVSHTIR  60
   61 RAELVNLVGL AGASNFTGDQ QKKLDVLGDE IFINAMRASG IIKVLVSEEQ EDLIVFPTNT 120
  121 GSYAVCCDPI DGSSNLDAGV SVGTIASIFR LLPDSSGTIN DVLRCGKEMV AACYAMYGSS 180
  181 THLVLTLGDG VDGFTLDTNL GEFILTHPN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 977.228787
Match: 1bk4A_
Description: Fructose-1,6-bisphosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fructose 1,6-bisphosphate 1-phosphatase activity 4.65500634914117 bayes_pls_golite062009
carbohydrate phosphatase activity 3.16528473469754 bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity 2.93988797179951 bayes_pls_golite062009
catalytic activity 2.13229228332707 bayes_pls_golite062009
phosphatase activity 1.80881730120084 bayes_pls_golite062009
phosphoric ester hydrolase activity 1.75330931312215 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.56919997723952 bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity 1.22694473598142 bayes_pls_golite062009
binding 0.97662061117191 bayes_pls_golite062009
inositol-1(or 4)-monophosphatase activity 0.0921499329725725 bayes_pls_golite062009
hydrolase activity 0.06056335004637 bayes_pls_golite062009
protein binding 0.0338617836572318 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [210-348] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRIPPQKAIY SINEGNTLYW NETIRTFIEK VKQPQADNNN KPFSARYVGS MVADVHRTFL  60
   61 YGGLFAYPCD KKSPNGKLRL LYEAFPMAFL MEQAGGKAVN DRGERILDLV PSHIHDKSSI 120
  121 WLGSSGEIDK FLDHIGKSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 977.228787
Match: 1bk4A_
Description: Fructose-1,6-bisphosphatase
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle