YRC Public Data Repository - Protein Structure Prediction

Protein:	DIC1
Organism:	Saccharomyces cerevisiae
Length:	298 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DIC1.

Description	E-value	Query Range	Subject Range
UCP3_BOVIN - Mitochondrial uncoupling protein 3 OS=Bos taurus GN=UCP3 PE=2 SV=1	6.0E-82	[1..293]	[1..303]
gi\|53829363, gi\|... - gi\|53829363\|gb\|AAU94638.1\| uncoupling protein 3 [Sus scrofa], gi\|4928052\|gb\|AAD33396.1\| uncoupling p...	6.0E-82	[1..293]	[1..303]
UCP3_MOUSE - Mitochondrial uncoupling protein 3 OS=Mus musculus GN=Ucp3 PE=1 SV=1	2.0E-81	[1..293]	[1..300]
UCP3_RAT - Mitochondrial uncoupling protein 3 OS=Rattus norvegicus GN=Ucp3 PE=2 SV=1	2.0E-81	[1..293]	[1..300]
UCP3_CANLF - Mitochondrial uncoupling protein 3 OS=Canis lupus familiaris GN=UCP3 PE=2 SV=1	4.0E-81	[1..293]	[1..303]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-80	[6..290]	[187..470]
gi\|151942810 - gi\|151942810\|gb\|EDN61156.1\| amino acid transporter [Saccharomyces cerevisiae YJM789] AGC1 - Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutama... AGC1_YEAST - Mitochondrial aspartate-glutamate transporter AGC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 /...	5.0E-80	[14..290]	[531..814]
UCP3 - uncoupling protein 3 (mitochondrial, proton carrier)	1.0E-79	[1..293]	[1..304]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTNAKESAG KNIKYPWWYG GAAGIFATMV THPLDLAKVR LQAAPMPKPT LFRMLESILA  60
   61 NEGVVGLYSG LSAAVLRQCT YTTVRFGAYD LLKENVIPRE QLTNMAYLLP CSMFSGAIGG 120
  121 LAGNFADVVN IRMQNDSALE AAKRRNYKNA IDGVYKIYRY EGGLKTLFTG WKPNMVRGIL 180
  181 MTASQVVTYD VFKNYLVTKL DFDASKNYTH LTASLLAGLV ATTVCSPADV MKTRIMNGSG 240
  241 DHQPALKILA DAVRKEGPSF MFRGWLPSFT RLGPFTMLIF FAIEQLKKHR VGMPKEDK

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.76
Match:	1is2A
Description:	Peroxisomal acyl-CoA oxidase-II, domains 3 and 4; Peroxisomal acyl-CoA oxidase-II, domains 1 and 2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits