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View Structure Prediction Details

Protein: SEC72
Organism: Saccharomyces cerevisiae
Length: 193 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC72.

Description E-value Query
Range		 Subject
Range
SEC72 - Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2...
SEC72_YEAST - Translocation protein SEC72 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC72 PE=1 S...
 3.0E-98 [1..193] [1..193]

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Predicted Domain #1
Region A:
Residues: [1-139] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTLEYNANS KLITASDAVV ALSTETNIDQ INVLTTSLIG ETNPNFTPQP NEALSKMIKG  60
   61 LFESGMKNLQ QKKLNEALKN VSLAIEMAQR KRAPWEAFAI QLPELHFMLR SKIDLCLILG 120
  121 KHLEALQDLD FLLGTGLIQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.950 0.291 endoplasmic reticulum membrane a.1.1 Globin-like
View Download 0.919 0.291 endoplasmic reticulum membrane a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.844 0.291 endoplasmic reticulum membrane a.1.1 Globin-like
View Download 0.829 0.291 endoplasmic reticulum membrane a.1.1 Globin-like
View Download 0.824 0.291 endoplasmic reticulum membrane a.4.3 ARID-like
View Download 0.819 0.291 endoplasmic reticulum membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.814 0.291 endoplasmic reticulum membrane f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.804 0.291 endoplasmic reticulum membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.796 0.291 endoplasmic reticulum membrane a.1.1 Globin-like
View Download 0.733 0.291 endoplasmic reticulum membrane a.7.4 Smac/diablo
View Download 0.728 0.291 endoplasmic reticulum membrane a.7.6 Ribosomal protein S20
View Download 0.695 0.291 endoplasmic reticulum membrane a.118.8 TPR-like
View Download 0.680 0.291 endoplasmic reticulum membrane a.25.1 Ferritin-like
View Download 0.667 0.291 endoplasmic reticulum membrane a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.661 0.291 endoplasmic reticulum membrane a.24.4 Hemerythrin
View Download 0.599 0.291 endoplasmic reticulum membrane a.60.9 lambda integrase-like, N-terminal domain
View Download 0.574 0.291 endoplasmic reticulum membrane a.29.2 Bromodomain
View Download 0.573 0.291 endoplasmic reticulum membrane a.24.9 alpha-catenin/vinculin
View Download 0.558 0.291 endoplasmic reticulum membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.550 0.291 endoplasmic reticulum membrane a.118.9 ENTH/VHS domain
View Download 0.540 0.291 endoplasmic reticulum membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.537 0.291 endoplasmic reticulum membrane a.146.1 Telomeric repeat binding factor (TRF) dimerisation domain
View Download 0.534 0.291 endoplasmic reticulum membrane a.118.8 TPR-like
View Download 0.528 0.291 endoplasmic reticulum membrane a.29.2 Bromodomain
View Download 0.524 0.291 endoplasmic reticulum membrane a.25.1 Ferritin-like
View Download 0.523 0.291 endoplasmic reticulum membrane c.78.2 Aspartate/glutamate racemase
View Download 0.522 0.291 endoplasmic reticulum membrane a.24.3 Cytochromes
View Download 0.522 0.291 endoplasmic reticulum membrane d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.521 0.291 endoplasmic reticulum membrane a.2.3 Chaperone J-domain
View Download 0.514 0.291 endoplasmic reticulum membrane d.58.26 GHMP Kinase, C-terminal domain
View Download 0.513 0.291 endoplasmic reticulum membrane a.1.1 Globin-like
View Download 0.509 0.291 endoplasmic reticulum membrane f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.489 0.291 endoplasmic reticulum membrane a.24.3 Cytochromes
View Download 0.486 0.291 endoplasmic reticulum membrane f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.482 0.291 endoplasmic reticulum membrane a.4.1 Homeodomain-like
View Download 0.478 0.291 endoplasmic reticulum membrane a.63.1 Apolipophorin-III
View Download 0.477 0.291 endoplasmic reticulum membrane a.74.1 Cyclin-like
View Download 0.471 0.291 endoplasmic reticulum membrane f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.457 0.291 endoplasmic reticulum membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.455 0.291 endoplasmic reticulum membrane a.26.1 4-helical cytokines
View Download 0.453 0.291 endoplasmic reticulum membrane a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.445 0.291 endoplasmic reticulum membrane a.118.8 TPR-like
View Download 0.442 0.291 endoplasmic reticulum membrane a.41.1 Domain of poly(ADP-ribose) polymerase
View Download 0.439 0.291 endoplasmic reticulum membrane a.26.1 4-helical cytokines
View Download 0.431 0.291 endoplasmic reticulum membrane a.142.1 PTS-regulatory domain, PRD
View Download 0.429 0.291 endoplasmic reticulum membrane a.91.1 Regulator of G-protein signalling, RGS
View Download 0.428 0.291 endoplasmic reticulum membrane a.25.1 Ferritin-like
View Download 0.426 0.291 endoplasmic reticulum membrane d.19.1 MHC antigen-recognition domain
View Download 0.417 0.291 endoplasmic reticulum membrane a.22.1 Histone-fold
View Download 0.415 0.291 endoplasmic reticulum membrane a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.398 0.291 endoplasmic reticulum membrane a.47.2 t-snare proteins
View Download 0.398 0.291 endoplasmic reticulum membrane d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.398 0.291 endoplasmic reticulum membrane a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.397 0.291 endoplasmic reticulum membrane a.7.1 Spectrin repeat
View Download 0.397 0.291 endoplasmic reticulum membrane a.26.1 4-helical cytokines
View Download 0.396 0.291 endoplasmic reticulum membrane d.54.1 Enolase N-terminal domain-like
View Download 0.396 0.291 endoplasmic reticulum membrane a.118.9 ENTH/VHS domain
View Download 0.395 0.291 endoplasmic reticulum membrane a.29.2 Bromodomain
View Download 0.391 0.291 endoplasmic reticulum membrane a.39.1 EF-hand
View Download 0.388 0.291 endoplasmic reticulum membrane f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.384 0.291 endoplasmic reticulum membrane a.47.2 t-snare proteins
View Download 0.376 0.291 endoplasmic reticulum membrane f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.375 0.291 endoplasmic reticulum membrane a.74.1 Cyclin-like
View Download 0.373 0.291 endoplasmic reticulum membrane f.18.1 F1F0 ATP synthase subunit A
View Download 0.373 0.291 endoplasmic reticulum membrane a.90.1 Transcription factor STAT-4 N-domain
View Download 0.371 0.291 endoplasmic reticulum membrane a.1.1 Globin-like
View Download 0.370 0.291 endoplasmic reticulum membrane f.13.1 Family A G protein-coupled receptor-like
View Download 0.369 0.291 endoplasmic reticulum membrane a.74.1 Cyclin-like
View Download 0.369 0.291 endoplasmic reticulum membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.365 0.291 endoplasmic reticulum membrane d.65.1 Hedgehog/DD-pepidase
View Download 0.362 0.291 endoplasmic reticulum membrane a.182.1 GatB/YqeY domain
View Download 0.360 0.291 endoplasmic reticulum membrane a.29.2 Bromodomain
View Download 0.351 0.291 endoplasmic reticulum membrane a.74.1 Cyclin-like
View Download 0.346 0.291 endoplasmic reticulum membrane f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.341 0.291 endoplasmic reticulum membrane a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.339 0.291 endoplasmic reticulum membrane a.118.8 TPR-like
View Download 0.335 0.291 endoplasmic reticulum membrane f.14.1 Voltage-gated potassium channels
View Download 0.330 0.291 endoplasmic reticulum membrane a.24.1 Apolipoprotein
View Download 0.328 0.291 endoplasmic reticulum membrane a.7.7 BAG domain
View Download 0.324 0.291 endoplasmic reticulum membrane a.118.1 ARM repeat
View Download 0.321 0.291 endoplasmic reticulum membrane a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.320 0.291 endoplasmic reticulum membrane a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.319 0.291 endoplasmic reticulum membrane a.72.1 Functional domain of the splicing factor Prp18
View Download 0.316 0.291 endoplasmic reticulum membrane a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.314 0.291 endoplasmic reticulum membrane c.52.1 Restriction endonuclease-like
View Download 0.309 0.291 endoplasmic reticulum membrane a.87.1 DBL homology domain (DH-domain)
View Download 0.309 0.291 endoplasmic reticulum membrane d.153.1 N-terminal nucleophile aminohydrolases (Ntn hydrolases)
View Download 0.308 0.291 endoplasmic reticulum membrane a.24.3 Cytochromes
View Download 0.306 0.291 endoplasmic reticulum membrane a.23.3 Methane monooxygenase hydrolase, gamma subunit
View Download 0.305 0.291 endoplasmic reticulum membrane f.14.1 Voltage-gated potassium channels
View Download 0.302 0.291 endoplasmic reticulum membrane a.25.1 Ferritin-like
View Download 0.301 0.291 endoplasmic reticulum membrane a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.298 0.291 endoplasmic reticulum membrane a.2.3 Chaperone J-domain
View Download 0.297 0.291 endoplasmic reticulum membrane d.79.1 YjgF-like
View Download 0.294 0.291 endoplasmic reticulum membrane a.118.16 Testis/brain RNA-binding protein (TB-RBP)
View Download 0.290 0.291 endoplasmic reticulum membrane a.35.1 lambda repressor-like DNA-binding domains
View Download 0.281 0.291 endoplasmic reticulum membrane a.89.1 Methyl-coenzyme M reductase alpha and beta chain C-terminal domain
View Download 0.276 0.291 endoplasmic reticulum membrane d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.272 0.291 endoplasmic reticulum membrane c.61.1 PRTase-like
View Download 0.265 0.291 endoplasmic reticulum membrane a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.263 0.291 endoplasmic reticulum membrane d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.262 0.291 endoplasmic reticulum membrane c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.256 0.291 endoplasmic reticulum membrane d.3.1 Cysteine proteinases
View Download 0.256 0.291 endoplasmic reticulum membrane a.26.1 4-helical cytokines
View Download 0.253 0.291 endoplasmic reticulum membrane d.185.1 LuxS/MPP-like metallohydrolase
View Download 0.251 0.291 endoplasmic reticulum membrane c.50.1 Macro domain-like
View Download 0.250 0.291 endoplasmic reticulum membrane a.118.11 Cytochrome c oxidase subunit E
View Download 0.250 0.291 endoplasmic reticulum membrane a.3.1 Cytochrome c
View Download 0.242 0.291 endoplasmic reticulum membrane a.131.1 Peridinin-chlorophyll protein
View Download 0.242 0.291 endoplasmic reticulum membrane b.82.7 Calcium ATPase, transduction domain A
View Download 0.235 0.291 endoplasmic reticulum membrane a.24.17 Group V grass pollen allergen
View Download 0.235 0.291 endoplasmic reticulum membrane a.61.1 Retroviral matrix proteins
View Download 0.230 0.291 endoplasmic reticulum membrane a.61.1 Retroviral matrix proteins
View Download 0.228 0.291 endoplasmic reticulum membrane a.3.1 Cytochrome c
View Download 0.224 0.291 endoplasmic reticulum membrane a.97.1 An anticodon-binding domain of class I aminoacyl-tRNA synthetases
View Download 0.222 0.291 endoplasmic reticulum membrane a.148.1 Arp2/3 complex 21 kDa subunit ARPC3
View Download 0.221 0.291 endoplasmic reticulum membrane d.67.3 Ribosome recycling factor, RRF
View Download 0.220 0.291 endoplasmic reticulum membrane f.13.1 Family A G protein-coupled receptor-like
View Download 0.219 0.291 endoplasmic reticulum membrane f.1.1 Colicin
View Download 0.214 0.291 endoplasmic reticulum membrane a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.213 0.291 endoplasmic reticulum membrane a.7.1 Spectrin repeat
View Download 0.212 0.291 endoplasmic reticulum membrane a.2.3 Chaperone J-domain
View Download 0.210 0.291 endoplasmic reticulum membrane a.24.9 alpha-catenin/vinculin
View Download 0.207 0.291 endoplasmic reticulum membrane a.129.1 GroEL equatorial domain-like
View Download 0.205 0.291 endoplasmic reticulum membrane a.7.8 GAT domain
View Download 0.201 0.291 endoplasmic reticulum membrane a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac

Predicted functions:

Term Confidence Notes
protein binding 1.91163869511795 bayes_pls_golite062009
binding 1.76895296443793 bayes_pls_golite062009
signal sequence binding 0.791153798439582 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [140-193] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDVFVRKADC LLKLRQWEEA RATCERGLAL APEDMKLRAL LIETARNLAE YNGE

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 4.823909
Match: PF00515
Description: Tetratricopeptide repeat

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle