YRC Public Data Repository - Protein Structure Prediction

Protein:	SEC22
Organism:	Saccharomyces cerevisiae
Length:	214 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SEC22.

Description	E-value	Query Range	Subject Range
VA722_ARATH - Vesicle-associated membrane protein 722 OS=Arabidopsis thaliana GN=VAMP722 PE=2 SV=2	7.0E-55	[1..197]	[6..195]
sec22 - SNARE Sec22 SEC22_SCHPO - Protein transport protein sec22 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=sec22 PE=2...	2.0E-53	[12..212]	[6..207]
gi\|190405329 - gi\|190405329\|gb\|EDV08596.1\| protein transport protein SEC22 [Saccharomyces cerevisiae RM11-1a] gi\|207342883 - gi\|207342883\|gb\|EDZ70513.1\| YLR268Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|151941103 - gi\|151941103\|gb\|EDN59483.1\| secretory subuint [Saccharomyces cerevisiae YJM789] SEC22 - R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and... SEC22_YEAST - Protein transport protein SEC22 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SEC22 PE...	3.0E-53	[1..214]	[1..214]
SC22B_RAT - Vesicle-trafficking protein SEC22b OS=Rattus norvegicus GN=Sec22b PE=1 SV=3 tr\|G3HP80\|G3HP80... - Vesicle-trafficking protein SEC22b OS=Cricetulus griseus GN=I79_012586 PE=4 SV=1 SEC22B - SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) gi\|109014715 - gi\|109014715\|ref\|XP_001114286.1\| PREDICTED: similar to SEC22 vesicle trafficking protein-like 1 [Mac... SC22B_MOUSE - Vesicle-trafficking protein SEC22b OS=Mus musculus GN=Sec22b PE=1 SV=3 SC22B_PONAB - Vesicle-trafficking protein SEC22b OS=Pongo abelii GN=SEC22B PE=2 SV=3 SC22B_PONPY - Vesicle-trafficking protein SEC22b - Pongo pygmaeus (Orangutan) ENSCJAT00000039187 - null gi\|123998251, gi... - gi\|123998251\|gb\|ABM86727.1\| SEC22 vesicle trafficking protein homolog B (S. cerevisiae) [synthetic c... ENSOCUP000000159... - pep:novel chromosome:oryCun2:13:44273276:44295283:-1 gene:ENSOCUG00000026877 transcript:ENSOCUT00000...	5.0E-53	[1..211]	[2..210]
gi\|14290512 - gi\|14290512\|gb\|AAH09024.1\| SEC22 vesicle trafficking protein homolog B (S. cerevisiae) [Mus musculus...	2.0E-52	[1..211]	[2..210]

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Predicted Domain #1

Region A:
Residues: [1-125]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKSTLIYRE DGLPLCTSVD NENDPSLFEQ KQKVKIVVSR LTPQSATEAT LESGSFEIHY  60
   61 LKKSMVYYFV ICESGYPRNL AFSYLNDIAQ EFEHSFANEY PKPTVRPYQF VNFDNFLQMT 120
  121 KKSYS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	216.0103
Match:	1ifqA_
Description:	Sec22b
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [126-214]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DKKVQDNLDQ LNQELVGVKQ IMSKNIEDLL YRGDSLDKMS DMSSSLKETS KRYRKSAQKI  60
   61 NFDLLISQYA PIVIVAFFFV FLFWWIFLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	72.156545
Match:	1gl2A_
Description:	Endobrevin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits