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View Structure Prediction Details

Protein: ERF2
Organism: Saccharomyces cerevisiae
Length: 359 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERF2.

Description E-value Query
Range
Subject
Range
ERFB_YEAST - Palmitoyltransferase ERF2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ERF2 PE=1 SV=1
ERF2 - Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety t...
5.0E-95 [1..359] [1..359]
ZDH23_ARATH - Probable protein S-acyltransferase 6 OS=Arabidopsis thaliana GN=PAT06 PE=2 SV=1
1.0E-67 [41..343] [15..314]
gi|190690819 - gi|190690819|gb|ACE87184.1| zinc finger, DHHC-type containing 9 protein [synthetic construct]
ZDHHC9 - zinc finger, DHHC-type containing 9
5.0E-63 [43..341] [7..306]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
1.0E-62 [43..341] [24..323]

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Predicted Domain #1
Region A:
Residues: [1-163]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALVSRRSTR SESTSITKEE HTGEGSLTKL FFRWLVTLEG DQDINDGKGY ISLPNVSNYI  60
   61 FFLGGRFRTV KGAKPLWLGV LLAIVCPMVL FSIFEAHKLW HTQNGYKVLV IFFYYFWVIT 120
  121 LASFIRTATS DPGVLPRNIH LSQLRNNYQI PQEYYNLITL PTH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.459 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.513 a.26.1 4-helical cytokines
View Download 0.473 a.25.1 Ferritin-like
View Download 0.478 a.26.1 4-helical cytokines
View Download 0.415 a.63.1 Apolipophorin-III
View Download 0.401 a.24.14 FAT domain of focal adhesion kinase
View Download 0.378 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.361 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.338 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.310 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.300 a.26.1 4-helical cytokines
View Download 0.300 a.25.1 Ferritin-like
View Download 0.283 a.63.1 Apolipophorin-III
View Download 0.280 a.26.1 4-helical cytokines
View Download 0.274 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.273 a.25.1 Ferritin-like
View Download 0.265 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.262 a.152.1 Antioxidant defence protein AhpD
View Download 0.254 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.252 a.26.1 4-helical cytokines
View Download 0.250 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.229 a.133.1 Phospholipase A2, PLA2
View Download 0.228 a.24.9 alpha-catenin/vinculin
View Download 0.226 a.24.12 Outer surface protein C (OspC)
View Download 0.225 a.26.1 4-helical cytokines
View Download 0.217 a.63.1 Apolipophorin-III
View Download 0.217 a.47.2 t-snare proteins
View Download 0.216 a.1.1 Globin-like
View Download 0.215 a.7.4 Smac/diablo
View Download 0.209 f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.207 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.206 a.25.1 Ferritin-like
View Download 0.201 a.148.1 Arp2/3 complex 21 kDa subunit ARPC3

Predicted functions:

Term Confidence Notes
transporter activity 1.29200212594063 bayes_pls_golite062009
transmembrane transporter activity 1.08174821699506 bayes_pls_golite062009
protein binding 0.646210551989356 bayes_pls_golite062009
binding 0.50942388426238 bayes_pls_golite062009
catalytic activity 0.481338897251745 bayes_pls_golite062009
active transmembrane transporter activity 0.304549276964021 bayes_pls_golite062009
primary active transmembrane transporter activity 0.295075718640555 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 0.00673253349876157 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [164-297]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSISKDITIK YCPSCRIWRP PRSSHCSTCN VCVMVHDHHC IWVNNCIGKR NYRFFLIFLL  60
   61 GAILSSVILL TNCAIHIARE SGGPRDCPVA ILLLCYAGLT LWYPAILFTY HIFMAGNQQT 120
  121 TREFLKGIGS KKNP

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 37.008774
Match: PF01529
Description: DHHC zinc finger domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [298-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VFHRVVKEEN IYNKGSFLKN MGHLMLEPRG PSFVSARKPH EAGDWRFMDL SPAHSFEKIQ  60
   61 KI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.333 b.36.1 PDZ domain-like
View Download 0.318 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.273 b.84.1 Single hybrid motif
View Download 0.544 d.9.2 Description not found.
View Download 0.392 d.9.2 Description not found.
View Download 0.259 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.247 b.89.1 Cyanovirin-N
View Download 0.242 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.241 b.55.1 PH domain-like
View Download 0.229 d.141.1 Ribosomal protein L6
View Download 0.222 a.60.2 RuvA domain 2-like
View Download 0.202 b.55.1 PH domain-like
View Download 0.201 g.27.1 Fibronectin type I module
View Download 0.201 d.50.2 Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle