YRC Public Data Repository - Protein Structure Prediction

Protein:	MAP1
Organism:	Saccharomyces cerevisiae
Length:	387 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MAP1.

Description	E-value	Query Range	Subject Range
MAP1_YEAST - Methionine aminopeptidase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MAP1 PE=1 SV... gi\|151941080 - gi\|151941080\|gb\|EDN59460.1\| methionine aminopeptidase [Saccharomyces cerevisiae YJM789] gi\|190405306 - gi\|190405306\|gb\|EDV08573.1\| methionine aminopeptidase [Saccharomyces cerevisiae RM11-1a] MAP1 - Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nasce...	0.0	[1..387]	[1..387]
MAP1A_ARATH - Methionine aminopeptidase 1A OS=Arabidopsis thaliana GN=MAP1A PE=1 SV=1	0.0	[14..380]	[2..391]
fma1 - methionine aminopeptidase Fma1 MAP1_SCHPO - Methionine aminopeptidase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fma1 PE=1 SV=1	0.0	[14..382]	[2..377]
gi\|168278507 - gi\|168278507\|dbj\|BAG11133.1\| methionine aminopeptidase 1 [synthetic construct] METAP1 - methionyl aminopeptidase 1	6.0E-98	[28..374]	[21..382]
gi\|220954982, gi... - gi\|220954982\|gb\|ACL90034.1\| CG13630-PA [synthetic construct], gi\|220945164\|gb\|ACL85125.1\| CG13630-PA... CG13630-PA - This gene is referred to in FlyBase by the symbol Dmel\CG13630 (CG13630, FBgn0039219). It is a prote...	5.0E-97	[22..374]	[5..361]
AMPP_ECOLI - (P15034) Xaa-Pro aminopeptidase (EC 3.4.11.9) (X-Pro aminopeptidase) (Aminopeptidase P II) (APP-II) ...	6.0E-79	[39..386]	[92..434]
gi\|83587696, gi\|... - gi\|83587696\|ref\|ZP_00926323.1\| COG0006: Xaa-Pro aminopeptidase [Escherichia coli 101-1], gi\|19443678... gi\|170082468, gi... - gi\|170082468\|ref\|YP_001731788.1\| proline aminopeptidase P II [Escherichia coli str. K-12 substr. DH1... AMPP_ECOLI - Xaa-Pro aminopeptidase (EC 3.4.11.9) (X-Pro aminopeptidase) (Aminopeptidase P II) (APP-II) (Aminoacy... EG10697 - proline aminopeptidase P II / Proline aminopeptidase, homotetrameric; aminopeptidase P gi\|238902033, gi... - gi\|238902033\|ref\|YP_002927829.1\| proline aminopeptidase P II [Escherichia coli BW2952], gi\|238863278... EG10697 - proline aminopeptidase P II / Proline aminopeptidase, homotetrameric; aminopeptidase P gi\|216529\|dbj\|BA... - aminopeptidase P precursor [Escherichia coli] gi\|85675720, gi\|... - gi\|89109687\|ref\|AP_003467.1\| proline aminopeptidase P II [Escherichia coli str. K-12 substr. W3110],...	6.0E-79	[39..386]	[93..435]
MAP12_MOUSE - Methionine aminopeptidase 1D, mitochondrial OS=Mus musculus GN=Metap1d PE=2 SV=1	1.0E-78	[79..377]	[43..334]
gi\|13363251, gi\|... - gi\|15833033\|ref\|NP_311806.1\| proline aminopeptidase P II [Escherichia coli O157:H7 str. Sakai], gi\|1... gi\|13363251, gi\|... - gi\|15833033\|ref\|NP_311806.1\| proline aminopeptidase P II [Escherichia coli O157:H7], gi\|13363251\|dbj... gi\|209760450, gi... - pir\|\|G85946 proline aminopeptidase P II [imported] - Escherichia coli (strain O157:H7, substrain ED... gi\|15803443, gi\|... - gi\|15803443\|ref\|NP_289476.1\| proline aminopeptidase P II [Escherichia coli O157:H7 EDL933], gi\|12517... gi\|254794857, gi... - gi\|254794857\|ref\|YP_003079694.1\| proline aminopeptidase P II [Escherichia coli O157:H7 str. TW14359]... gi\|217326697, gi... - gi\|217326697\|ref\|ZP_03442780.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. TW14588], gi\|2... gi\|195936526 - gi\|195936526\|ref\|ZP_03081908.1\| proline aminopeptidase P II [Escherichia coli O157:H7 str. EC4024] gi\|208733741, gi... - gi\|208812464\|ref\|ZP_03253793.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4045], gi\|20... gi\|208741670, gi... - gi\|208821547\|ref\|ZP_03261867.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4042], gi\|20... gi\|209398591, gi... - gi\|209398591\|ref\|YP_002272384.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4115], gi\|2... gi\|168775788, gi... - gi\|187768811\|gb\|EDU32655.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4196], gi\|168775... gi\|168778924, gi... - gi\|189003609\|gb\|EDU72595.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4076], gi\|168778... gi\|168785757, gi... - gi\|189373889\|gb\|EDU92305.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC869], gi\|1687857... gi\|189377684, gi... - gi\|189377684\|gb\|EDU96100.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC508], gi\|1688000... gi\|168747610, gi... - gi\|188017799\|gb\|EDU55921.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4113], gi\|168747... gi\|189358530, gi... - gi\|189358530\|gb\|EDU76949.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4401], gi\|168753... gi\|189369256, gi... - gi\|189369256\|gb\|EDU87672.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4501], gi\|168760... gi\|189363746, gi... - gi\|189363746\|gb\|EDU82165.1\| Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4486], gi\|168766...	1.0E-78	[39..386]	[93..435]

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Predicted Domain #1

Region A:
Residues: [1-115]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTATTTVTT SDQASHPTKI YCSGLQCGRE TSSQMKCPVC LKQGIVSIFC DTSCYENNYK  60
   61 AHKALHNAKD GLEGAYDPFP KFKYSGKVKA SYPLTPRRYV PEDIPKPDWA ANGLP

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [116-387]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VSEQRNDRLN NIPIYKKDQI KKIRKACMLG REVLDIAAAH VRPGITTDEL DEIVHNETIK  60
   61 RGAYPSPLNY YNFPKSLCTS VNEVICHGVP DKTVLKEGDI VNLDVSLYYQ GYHADLNETY 120
  121 YVGENISKEA LNTTETSREC LKLAIKMCKP GTTFQELGDH IEKHATENKC SVVRTYCGHG 180
  181 VGEFFHCSPN IPHYAKNRTP GVMKPGMVFT IEPMINEGTW KDMTWPDDWT STTQDGKLSA 240
  241 QFEHTLLVTE HGVEILTARN KKSPGGPRQR IK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	651.68867
Match:	4matA_
Description:	Methionine aminopeptidase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits