YRC Public Data Repository - Protein Structure Prediction

Protein:	CCC1
Organism:	Saccharomyces cerevisiae
Length:	322 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCC1.

Description	E-value	Query Range	Subject Range
gi\|151941060 - gi\|151941060\|gb\|EDN59440.1\| cross-complements Ca(2+) phenotype of csg1 [Saccharomyces cerevisiae YJM... CCC1 - Putative vacuolar Fe2+/Mn2+ transporter; suppresses respiratory deficit of yfh1 mutants, which lack ... CCC1_YEAST - Protein CCC1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CCC1 PE=1 SV=1 gi\|190405285 - gi\|190405285\|gb\|EDV08552.1\| transmembrane Ca2+ transporter [Saccharomyces cerevisiae RM11-1a]	1.0E-83	[1..322]	[1..322]
gi\|18893429, gi\|... - gi\|18977697\|ref\|NP_579054.1\| hypothetical protein PF1325 [Pyrococcus furiosus DSM 3638], gi\|18893429...	5.0E-59	[48..321]	[92..353]
gi\|7518580 - pir\|\|B71139 hypothetical protein PH0325 - Pyrococcus horikoshii gi\|14590242, gi\|... - gi\|3256716\|dbj\|BAA29399.1\| 364aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14590242\|...	1.0E-58	[48..321]	[92..355]
gi\|7518076, gi\|5... - pir\|\|E75012 hypothetical protein PAB1273 - Pyrococcus abyssi (strain Orsay), gi\|5459053\|emb\|CAB50539... gi\|5459053, gi\|1... - gi\|5459053\|emb\|CAB50539.1\| Membrane protein, putative [Pyrococcus abyssi GE5], gi\|14521833\|ref\|NP_12...	2.0E-57	[48..321]	[92..355]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-56	[82..322]	[3..239]
gi\|5732897 - gi\|5732897\|gb\|AAD49328.1\|AF162938_1 H3U [Streptomyces coelicolor A3(2)]	6.0E-56	[84..322]	[1..235]
gi\|15899300, gi\|... - gi\|15899300\|ref\|NP_343905.1\| hypothetical protein SSO2568 [Sulfolobus solfataricus P2], gi\|13815872\|... gi\|241769614, gi... - gi\|241769614\|ref\|ZP_04767033.1\| protein of unknown function DUF125 transmembrane [Sulfolobus solfata... gi\|25356849 - pir\|\|H90429 membrane conserved hypothetical protein SSO2568 [imported] - Sulfolobus solfataricus	3.0E-53	[48..320]	[94..346]
gi\|56552756, gi\|... - gi\|56552756\|ref\|YP_163595.1\| nodulin 21 like protein [Zymomonas mobilis subsp. mobilis ZM4], gi\|5654... gi\|6478223 - gi\|6478223\|gb\|AAF13747.1\|AF117351_4 unknown [Zymomonas mobilis subsp. mobilis ZM4]	9.0E-53	[85..322]	[5..233]
VIT1_ARATH - Vacuolar iron transporter 1 OS=Arabidopsis thaliana GN=VIT1 PE=2 SV=1	1.0E-52	[72..321]	[2..248]

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Predicted Domain #1

Region A:
Residues: [1-78]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIVALKNAV VTLIQKAKGS GGTSELGGSE STPLLRGSNS NSSRHDNLSS SSSDIIYGRN  60
   61 SAQDLENSPM SVGKDNRN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.509	0.982	cellular manganese ion homeostasis	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.223	0.982	cellular manganese ion homeostasis	a.24.7	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)

Predicted Domain #2

Region A:
Residues: [79-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDNGSDNEKA NLGFFQSVDP RVISDLIIGL SDGLTVPFAL TAGLSSLGDA KLVITGGFAE  60
   61 LISGAISMGL GGYLGAKSES DYYHAEVKKE KRKFYDNSNL INREIEDILL EINPNFSDET 120
  121 IVSFIKDLQR TPELMVDFII RYGRGLDEPA ENRELISAVT IGGGYLLGGL VPLVPYFFVS 180
  181 DVGTGLIYSI IVMVVTLFWF GYVKTKLSMG SGSSTSKKVT EGVEMVVVGG VAAGAAWFFV 240
  241 KLLG

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	3.026872
Match:	PF01988
Description:	Integral membrane protein DUF125

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits