| Protein: | FRE1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 686 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FRE1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..686] | [1..686] |
|
|
0.0 | [22..686] | [33..706] |
|
|
0.0 | [172..684] | [335..921] |
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0.0 | [172..684] | [335..921] |
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0.0 | [174..684] | [330..938] |
|
Region A: Residues: [1-144] |
1 11 21 31 41 51
| | | | | |
1 MVRTRVLFCL FISFFATVQS SATLISTSCI SQAALYQFGC SSKSKSCYCK NINWLGSVTA 60
61 CAYENSKSNK TLDSALMKLA SQCSSIKVYT LEDMKNIYLN ASNYLRAPEK SDKKTVVSQP 120
121 LMANETAYHY YYEENYGIHL NLMR
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.269 | a.1.1 | Globin-like |
| View | Download | 0.250 | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.250 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.284 | a.74.1 | Cyclin-like |
| View | Download | 0.251 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.211 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.208 | a.1.1 | Globin-like |
| View | Download | 0.207 | a.40.2 | X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain |
| View | Download | 0.201 | a.1.1 | Globin-like |
|
Region A: Residues: [145-331] |
1 11 21 31 41 51
| | | | | |
1 SQWCAWGLVF FWVAVLTAAT ILNILKRVFG KNIMANSVKK SLIYPSVYKD YNERTFYLWK 60
61 RLPFNFTTRG KGLVVLIFVI LTILSLSFGH NIKLPHPYDR PRWRRSMAFV SRRADLMAIA 120
121 LFPVVYLFGI RNNPFIPITG LSFSTFNFYH KWSAYVCFML AVVHSIVMTA SGVKRGVFQS 180
181 LVRKFYF
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [332-386] |
1 11 21 31 41 51
| | | | | |
1 RWGIVATILM SIIIFQSEKV FRNRGYEIFL LIHKAMNIMF IIAMYYHCHT LGWMG
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| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.600 | a.4.1 | Homeodomain-like |
| View | Download | 0.588 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.580 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.611 | a.50.1 | Anaphylotoxins (complement system) |
| View | Download | 0.580 | a.4.1 | Homeodomain-like |
| View | Download | 0.568 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.549 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.535 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.526 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.456 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.451 | a.2.7 | tRNA-binding arm |
| View | Download | 0.408 | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| View | Download | 0.407 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.390 | a.4.1 | Homeodomain-like |
| View | Download | 0.389 | a.135.1 | Tetraspanin |
| View | Download | 0.387 | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.379 | a.30.1 | ROP protein |
| View | Download | 0.375 | a.4.1 | Homeodomain-like |
| View | Download | 0.372 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.359 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.341 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.333 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.327 | a.4.1 | Homeodomain-like |
| View | Download | 0.325 | a.65.1 | Annexin |
| View | Download | 0.320 | a.8.1 | Bacterial immunoglobulin/albumin-binding domains |
| View | Download | 0.318 | a.153.1 | Nuclear receptor coactivator interlocking domain |
| View | Download | 0.317 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.314 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.310 | a.112.1 | Description not found. |
| View | Download | 0.295 | a.2.3 | Chaperone J-domain |
| View | Download | 0.282 | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.278 | a.55.1 | IHF-like DNA-binding proteins |
| View | Download | 0.274 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.272 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.272 | d.120.1 | Cytochrome b5 |
| View | Download | 0.272 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.264 | a.101.1 | Uteroglobin-like |
| View | Download | 0.261 | a.4.10 | N-terminal Zn binding domain of HIV integrase |
| View | Download | 0.250 | a.112.1 | Description not found. |
| View | Download | 0.250 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.249 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.245 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.241 | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.236 | a.7.8 | GAT domain |
| View | Download | 0.228 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.226 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.224 | a.2.7 | tRNA-binding arm |
| View | Download | 0.223 | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.221 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.220 | a.3.1 | Cytochrome c |
| View | Download | 0.213 | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.211 | d.54.1 | Enolase N-terminal domain-like |
| View | Download | 0.208 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.208 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.202 | a.4.1 | Homeodomain-like |
| View | Download | 0.202 | f.17.1 | F1F0 ATP synthase subunit C |
|
Region A: Residues: [387-516] |
1 11 21 31 41 51
| | | | | |
1 WIWSMAGILC FDRFCRIVRI IMNGGLKTAT LSTTDDSNVI KISVKKPKFF KYQVGAFAYM 60
61 YFLSPKSAWF YSFQSHPFTV LSERHRDPNN PDQLTMYVKA NKGITRVLLS KVLSAPNHTV 120
121 DCKIFLEGPY
|
| Detection Method: | |
| Confidence: | 52.69897 |
| Match: | 1cnf__ |
| Description: | Nitrate reductase core domain; Nitrate reductase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| catalytic activity | 1.45374095556065 | bayes_pls_golite062009 |
| transferase activity | 1.15480450573972 | bayes_pls_golite062009 |
| binding | 1.13408475648113 | bayes_pls_golite062009 |
| oxidoreductase activity | 0.27336340260908 | bayes_pls_golite062009 |
| protein binding | 0.144900113694048 | bayes_pls_golite062009 |
| cofactor binding | 0.0731141170494622 | bayes_pls_golite062009 |
|
Region A: Residues: [517-686] |
1 11 21 31 41 51
| | | | | |
1 GVTVPHIAKL KRNLVGVAAG LGVAAIYPHF VECLRLPSTD QLQHKFYWIV NDLSHLKWFE 60
61 NELQWLKEKS CEVSVIYTGS SVEDTNSDES TKGFDDKEES EITVECLNKR PDLKELVRSE 120
121 IKLSELENNN ITFYSCGPAT FNDDFRNAVV QGIDSSLKID VELEEESFTW
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| Detection Method: | |
| Confidence: | 52.69897 |
| Match: | 1cnf__ |
| Description: | Nitrate reductase core domain; Nitrate reductase |
| Matching Structure (courtesy of the PDB): |
|
