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View Structure Prediction Details

Protein: CLB4
Organism: Saccharomyces cerevisiae
Length: 460 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLB4.

Description E-value Query
Range
Subject
Range
CLB4 - B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; m...
CG24_YEAST - G2/mitotic-specific cyclin-4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CLB4 PE=1 S...
0.0 [1..460] [1..460]
CCN1_ANTMA - G2/mitotic-specific cyclin-1 OS=Antirrhinum majus PE=2 SV=1
0.0 [26..456] [8..444]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [24..460] [11..448]
gi|9502284 - gi|9502284|gb|AAF88072.1| cyclin [Cicer arietinum]
0.0 [26..456] [8..446]
gi|1835260 - gi|1835260|emb|CAA99990.1| mitotic cyclin [Sesbania rostrata]
0.0 [19..459] [3..441]
CCNB1_SOYBN - G2/mitotic-specific cyclin S13-6 OS=Glycine max PE=2 SV=1
0.0 [19..459] [3..447]
gi|7271222 - gi|7271222|emb|CAB81558.1| cyclin B1 [Nicotiana tabacum]
0.0 [25..458] [3..414]
gi|2570145 - gi|2570145|dbj|BAA22991.1| cyclin A [Hemicentrotus pulcherrimus]
0.0 [20..459] [4..458]

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Predicted Domain #1
Region A:
Residues: [1-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLEGYTVQP PQSTLIGDIE IQDENANQEV KNVLYQGVQK GIKRLEKRQR RVALGDVTSQ  60
   61 KANKIHNAIH NKFHQTKNNF EIENIRSSAL VKEQQRDVRH EDSDYFLIDS SEGSSTDDEQ 120
  121 VNEDAIDDLL SRRVNDQQIQ ADEVYEDFDG EMQDVIEEDV DSQIEPLSPI NNDEIQTELD 180
  181 RAFEKYFRSV PNPLDDDTHD V

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [202-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VMVVEYASDI FYYLRE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [340-460]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PMPFLRRISK ADDYDFEPRT LAKYLLETTI VEPKLVAAAP SWLAAGAYFL SRTILGSNDW  60
   61 SLKHVFYSGY TSSQIIPLAS LILENCKNAS RRHHSIWKKY FDQKHYRCSQ IVEEWIVSTE 120
  121 A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 396.626727
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [218-339]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LEVKYRPNPY YMQNQVELTW PFRRTMIDWL VQLHFRFQLL PETLYLTINI VDRFLSKKTV  60
   61 TLNRFQLVGV SALFIAAKFE EINCPTLDDL VYMLENTYTR DDIIRAEQYM IDTLEFEIGW 120
  121 PG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 396.626727
Match: 1vin__
Description: Cyclin A
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle