| Protein: | PEX13 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 386 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEX13.
| Description | E-value | Query Range |
Subject Range |
|
|
2.0E-96 | [1..386] | [1..386] |
|
|
5.0E-75 | [1..385] | [1..349] |
|
|
3.0E-74 | [1..383] | [1..349] |
|
|
4.0E-74 | [1..383] | [1..349] |
|
|
2.0E-48 | [75..384] | [1..292] |
|
|
3.0E-45 | [123..372] | [49..288] |
|
|
7.0E-29 | [211..377] | [242..393] |
|
Region A: Residues: [1-109] |
1 11 21 31 41 51
| | | | | |
1 MSSTAVPRPK PWETSASLEE PQRNAQSLSA MMTSNQQDSR PTEESNNSNS ASESAPEVLP 60
61 RPAALNSSGT YGESNTIPGI YGNSNYGIPY DNNPYSMNSI YGNSIGRYG
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.246 | 0.461 | peroxisomal membrane | c.47.1 | Thioredoxin-like |
| View | Download | 0.239 | 0.056 | peroxisomal membrane | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.303 | 0.051 | peroxisomal membrane | a.74.1 | Cyclin-like |
| View | Download | 0.370 | 0.006 | peroxisomal membrane | a.70.1 | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
| View | Download | 0.370 | N/A | N/A | a.70.1 | N-terminal domain of the delta subunit of the F1F0-ATP synthase |
| View | Download | 0.303 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.246 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.239 | N/A | N/A | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.238 | N/A | N/A | c.47.1 | Thioredoxin-like |
| View | Download | 0.236 | N/A | N/A | d.99.1 | Ribosomal protein L9 C-domain |
| View | Download | 0.226 | N/A | N/A | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.204 | N/A | N/A | c.47.1 | Thioredoxin-like |
|
Region A: Residues: [110-198] |
1 11 21 31 41 51
| | | | | |
1 YGGSYYGNNY GSFYGGGYGA GAGYGMNNGS GLGESTKATF QLIESLIGAV TGFAQMLEST 60
61 YMATHNSFFT MISVAEQFGN LKEMLGSFF
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.910 | 0.056 | peroxisomal membrane | a.7.8 | GAT domain |
| View | Download | 0.714 | 0.056 | peroxisomal membrane | a.47.2 | t-snare proteins |
| View | Download | 0.675 | 0.056 | peroxisomal membrane | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.857 | 0.056 | peroxisomal membrane | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.910 | 0.056 | peroxisomal membrane | a.7.8 | GAT domain |
| View | Download | 0.857 | 0.056 | peroxisomal membrane | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.716 | 0.056 | peroxisomal membrane | a.7.8 | GAT domain |
| View | Download | 0.716 | 0.056 | peroxisomal membrane | a.7.8 | GAT domain |
| View | Download | 0.714 | 0.056 | peroxisomal membrane | a.47.2 | t-snare proteins |
| View | Download | 0.675 | 0.056 | peroxisomal membrane | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.673 | 0.056 | peroxisomal membrane | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.663 | 0.056 | peroxisomal membrane | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.632 | 0.056 | peroxisomal membrane | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.603 | 0.056 | peroxisomal membrane | a.24.3 | Cytochromes |
| View | Download | 0.571 | 0.056 | peroxisomal membrane | a.24.3 | Cytochromes |
| View | Download | 0.568 | 0.056 | peroxisomal membrane | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.554 | 0.056 | peroxisomal membrane | a.47.2 | t-snare proteins |
| View | Download | 0.553 | 0.056 | peroxisomal membrane | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.534 | 0.056 | peroxisomal membrane | a.7.1 | Spectrin repeat |
| View | Download | 0.532 | 0.056 | peroxisomal membrane | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.508 | 0.056 | peroxisomal membrane | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.497 | 0.056 | peroxisomal membrane | d.110.4 | SNARE-like |
| View | Download | 0.444 | 0.056 | peroxisomal membrane | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.436 | 0.056 | peroxisomal membrane | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.436 | 0.056 | peroxisomal membrane | a.22.1 | Histone-fold |
| View | Download | 0.430 | 0.056 | peroxisomal membrane | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.409 | 0.056 | peroxisomal membrane | a.24.3 | Cytochromes |
| View | Download | 0.409 | 0.056 | peroxisomal membrane | a.24.3 | Cytochromes |
| View | Download | 0.397 | 0.056 | peroxisomal membrane | d.110.4 | SNARE-like |
| View | Download | 0.365 | 0.056 | peroxisomal membrane | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.362 | 0.056 | peroxisomal membrane | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.362 | 0.056 | peroxisomal membrane | a.47.2 | t-snare proteins |
| View | Download | 0.354 | 0.056 | peroxisomal membrane | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.350 | 0.056 | peroxisomal membrane | a.22.1 | Histone-fold |
| View | Download | 0.345 | 0.056 | peroxisomal membrane | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.339 | 0.056 | peroxisomal membrane | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.337 | 0.056 | peroxisomal membrane | a.46.1 | Methionine synthase domain |
| View | Download | 0.335 | 0.056 | peroxisomal membrane | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.331 | 0.056 | peroxisomal membrane | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.330 | 0.056 | peroxisomal membrane | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.326 | 0.056 | peroxisomal membrane | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.326 | 0.056 | peroxisomal membrane | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.323 | 0.056 | peroxisomal membrane | a.47.2 | t-snare proteins |
| View | Download | 0.316 | 0.056 | peroxisomal membrane | a.112.1 | Description not found. |
| View | Download | 0.315 | 0.056 | peroxisomal membrane | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.313 | 0.056 | peroxisomal membrane | a.47.2 | t-snare proteins |
| View | Download | 0.307 | 0.056 | peroxisomal membrane | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.305 | 0.056 | peroxisomal membrane | a.24.3 | Cytochromes |
| View | Download | 0.304 | 0.056 | peroxisomal membrane | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.301 | 0.056 | peroxisomal membrane | a.29.2 | Bromodomain |
| View | Download | 0.290 | 0.056 | peroxisomal membrane | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.290 | 0.056 | peroxisomal membrane | a.7.8 | GAT domain |
| View | Download | 0.290 | 0.056 | peroxisomal membrane | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.281 | 0.056 | peroxisomal membrane | a.65.1 | Annexin |
| View | Download | 0.281 | 0.056 | peroxisomal membrane | a.24.3 | Cytochromes |
| View | Download | 0.280 | 0.056 | peroxisomal membrane | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.280 | 0.056 | peroxisomal membrane | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.279 | 0.056 | peroxisomal membrane | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.271 | 0.056 | peroxisomal membrane | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.270 | 0.056 | peroxisomal membrane | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.269 | 0.056 | peroxisomal membrane | a.29.5 | alpha-ketoacid dehydrogenase kinase, N-terminal domain |
| View | Download | 0.269 | 0.056 | peroxisomal membrane | a.158.1 | F-box domain |
| View | Download | 0.266 | 0.056 | peroxisomal membrane | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.262 | 0.056 | peroxisomal membrane | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.261 | 0.056 | peroxisomal membrane | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.261 | 0.056 | peroxisomal membrane | f.1.3 | delta-Endotoxin (insectocide), N-terminal domain |
| View | Download | 0.260 | 0.056 | peroxisomal membrane | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.259 | 0.056 | peroxisomal membrane | a.29.2 | Bromodomain |
| View | Download | 0.259 | 0.056 | peroxisomal membrane | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.259 | 0.056 | peroxisomal membrane | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.259 | 0.056 | peroxisomal membrane | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.256 | 0.056 | peroxisomal membrane | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.256 | 0.056 | peroxisomal membrane | a.22.1 | Histone-fold |
| View | Download | 0.255 | 0.056 | peroxisomal membrane | a.2.11 | Fe,Mn superoxide dismutase (SOD), N-terminal domain |
| View | Download | 0.254 | 0.056 | peroxisomal membrane | a.22.1 | Histone-fold |
| View | Download | 0.253 | 0.056 | peroxisomal membrane | a.62.1 | Hepatitis B viral capsid (hbcag) |
| View | Download | 0.251 | 0.056 | peroxisomal membrane | a.7.1 | Spectrin repeat |
| View | Download | 0.250 | 0.056 | peroxisomal membrane | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.245 | 0.056 | peroxisomal membrane | d.43.1 | Elongation factor Ts (EF-Ts), dimerisation domain |
| View | Download | 0.245 | 0.056 | peroxisomal membrane | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.241 | 0.056 | peroxisomal membrane | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.241 | 0.056 | peroxisomal membrane | a.25.1 | Ferritin-like |
| View | Download | 0.238 | 0.056 | peroxisomal membrane | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.233 | 0.056 | peroxisomal membrane | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.233 | 0.056 | peroxisomal membrane | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.233 | 0.056 | peroxisomal membrane | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.230 | 0.056 | peroxisomal membrane | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.228 | 0.056 | peroxisomal membrane | a.22.1 | Histone-fold |
| View | Download | 0.224 | 0.056 | peroxisomal membrane | a.30.1 | ROP protein |
| View | Download | 0.224 | 0.056 | peroxisomal membrane | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.223 | 0.056 | peroxisomal membrane | a.7.8 | GAT domain |
| View | Download | 0.223 | 0.056 | peroxisomal membrane | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.222 | 0.056 | peroxisomal membrane | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.222 | 0.056 | peroxisomal membrane | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.218 | 0.056 | peroxisomal membrane | a.7.8 | GAT domain |
| View | Download | 0.215 | 0.056 | peroxisomal membrane | a.22.1 | Histone-fold |
| View | Download | 0.214 | 0.056 | peroxisomal membrane | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.214 | 0.056 | peroxisomal membrane | f.17.1 | F1F0 ATP synthase subunit C |
| View | Download | 0.212 | 0.056 | peroxisomal membrane | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.211 | 0.056 | peroxisomal membrane | a.60.13 | Putative methyltransferase TM0872, insert domain |
| View | Download | 0.210 | 0.056 | peroxisomal membrane | a.29.2 | Bromodomain |
| View | Download | 0.209 | 0.056 | peroxisomal membrane | a.47.2 | t-snare proteins |
| View | Download | 0.208 | 0.056 | peroxisomal membrane | a.47.2 | t-snare proteins |
| View | Download | 0.208 | 0.056 | peroxisomal membrane | d.192.1 | YlxR-like |
| View | Download | 0.206 | 0.056 | peroxisomal membrane | a.29.2 | Bromodomain |
| View | Download | 0.202 | 0.056 | peroxisomal membrane | a.12.1 | Kix domain of CBP (creb binding protein) |
| View | Download | 0.201 | 0.056 | peroxisomal membrane | a.30.1 | ROP protein |
| View | Download | 0.201 | 0.056 | peroxisomal membrane | a.30.1 | ROP protein |
| View | Download | 0.201 | 0.056 | peroxisomal membrane | a.22.1 | Histone-fold |
| View | Download | 0.201 | 0.056 | peroxisomal membrane | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
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Region A: Residues: [199-302] |
1 11 21 31 41 51
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1 GIFAIMKFLK KILYRATKGR LGIPPKNFAE SEGSKNKLIE DFQKFNDSGT INSNEKATRR 60
61 KISWKPLLFF LMAVFGFPYL LNKFITKLQT SGTIRASQGN GSEP
|
| Detection Method: | |
| Confidence: | 6.0 |
| Match: | 1bmbA_ |
| Description: | Growth factor receptor-bound protein 2 (GRB2) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.55003340159545 | bayes_pls_golite062009 |
| protein binding | 2.35325421236395 | bayes_pls_golite062009 |
| molecular adaptor activity | 0.68555837423221 | bayes_pls_golite062009 |
| signal transducer activity | 0.644330423191792 | bayes_pls_golite062009 |
| molecular transducer activity | 0.644330423191792 | bayes_pls_golite062009 |
| hydrolase activity | 0.31081944790532 | bayes_pls_golite062009 |
| protein binding, bridging | 0.230308623372106 | bayes_pls_golite062009 |
| receptor binding | 0.00920732436841987 | bayes_pls_golite062009 |
|
Region A: Residues: [303-386] |
1 11 21 31 41 51
| | | | | |
1 IDPSKLEFAR ALYDFVPENP EMEVALKKGD LMAILSKKDP LGRDSDWWKV RTKNGNIGYI 60
61 PYNYIEIIKR RKKIEHVDDE TRTH
|
| Detection Method: | |
| Confidence: | 63.39794 |
| Match: | 1aww__ |
| Description: | Bruton's tyrosine kinase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.49184519104882 | bayes_pls_golite062009 |
| protein binding | 2.29371158534719 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.67112127425228 | bayes_pls_golite062009 |
| transporter activity | 1.30447542854757 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.08558010881058 | bayes_pls_golite062009 |
| actin binding | 0.75525840382431 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.566172161499832 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.325817349097199 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.00508584255499911 | bayes_pls_golite062009 |
