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View Structure Prediction Details

Protein: SKG3
Organism: Saccharomyces cerevisiae
Length: 1026 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SKG3.

Description E-value Query
Range
Subject
Range
SKG3 - Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell pe...
SKG3_YEAST - Protein SKG3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SKG3 PE=1 SV=1
0.0 [1..1026] [1..1026]
gi|8163674 - gi|8163674|gb|AAF73795.1|AF154026_1 surface protein PspC [Streptococcus pneumoniae]
7.0E-60 [518..975] [38..474]
gi|25509405, gi|... - gi|8163644|gb|AAF73779.1| surface protein PspC [Streptococcus pneumoniae], pir||H98120 choline bindi...
gi|15459699, gi|... - gi|15904036|ref|NP_359586.1| choline binding protein A [Streptococcus pneumoniae R6], gi|15459699|gb...
gi|116515359, gi... - gi|8163644|gb|AAF73779.1|AF154012_1 surface protein PspC [Streptococcus pneumoniae], gi|116515359|re...
5.0E-57 [518..966] [38..483]

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Predicted Domain #1
Region A:
Residues: [1-72]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRIFSGVKS PKLSAPPKVF KNDESPSTPS SPKFDQGLRS LSASASRLFS NSISTPGSPT  60
   61 LDLPQEHSIN GD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.343 a.4.5 "Winged helix" DNA-binding domain
View Download 0.388 a.4.1 Homeodomain-like
View Download 0.367 a.51.1 Cytochrome c oxidase subunit h
View Download 0.337 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.388 a.4.1 Homeodomain-like
View Download 0.367 a.51.1 Cytochrome c oxidase subunit h
View Download 0.343 a.4.5 "Winged helix" DNA-binding domain
View Download 0.339 a.4.5 "Winged helix" DNA-binding domain
View Download 0.337 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.324 a.4.1 Homeodomain-like
View Download 0.290 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.271 a.4.1 Homeodomain-like
View Download 0.246 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.215 a.28.2 Colicin E immunity proteins
View Download 0.214 a.64.1 Saposin

Predicted Domain #2
Region A:
Residues: [73-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISPELVPIVT LLSAQAHRRY HYGIFLILHD LKTDGTPAAR QWEECYGVLL GTQLALWDAK  60
   61 ELSDSKNNKN TSTMKKAASR PSFINFTDAS VRSLDANDQV IIASENEKTK KDLDNVLVVS 120
  121 TTLKNRYFLK FKNSKSFKTW NAAIRLSLFE FTALQEAYTG SFLSSRGVKL GDIKVVMADT 180
  181 KFTYEDWVSV RFGTGMPWKR CYAVIS

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 8.356547
Match: PF00169
Description: PH domain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.37468867147476 bayes_pls_golite062009
protein binding 1.98056222560389 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [279-350]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSGKKKKNS KGSICFYENN KKTKKSNIMT TVVDARALYA VYPSSPILID TSTIIKLEGF  60
   61 VSFDKSEEPQ ET

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.333 a.3.1 Cytochrome c
View Download 0.407 d.58.17 Metal-binding domain
View Download 0.342 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.446 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.344 a.135.1 Tetraspanin
View Download 0.268 d.64.1 eIF1-like
View Download 0.265 a.2.9 C-terminal UvrC-binding domain of UvrB
View Download 0.203 a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #4
Region A:
Residues: [351-451]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLFIMPEKHQ GVPGYDTIIR FLIPAMNAFY LYGRPKGLIA NRTDPDSLLF ALPTLPHIYY  60
   61 LQVDDVLSLT KDKNYIHWSA ADWRNNIVQV LQKKLSKGYK G

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.466 0.964 cellular bud a.39.1 EF-hand
View Download 0.449 0.002 cellular bud a.156.1 S13-like H2TH domain
View Download 0.804 0.002 cellular bud a.158.1 F-box domain
View Download 0.517 0.001 cellular bud a.24.17 Group V grass pollen allergen
View Download 0.760 N/A N/A a.39.4 Hypothetical protein MTH865
View Download 0.349 N/A N/A a.74.1 Cyclin-like
View Download 0.327 N/A N/A a.74.1 Cyclin-like
View Download 0.319 N/A N/A a.74.1 Cyclin-like
View Download 0.294 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.293 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.292 N/A N/A a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.286 N/A N/A a.74.1 Cyclin-like
View Download 0.280 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.273 N/A N/A a.24.4 Hemerythrin
View Download 0.262 N/A N/A d.110.4 SNARE-like
View Download 0.254 N/A N/A a.18.1 T4 endonuclease V
View Download 0.254 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.251 N/A N/A a.74.1 Cyclin-like
View Download 0.251 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.246 N/A N/A d.110.1 Profilin (actin-binding protein)
View Download 0.246 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.245 N/A N/A d.110.1 Profilin (actin-binding protein)
View Download 0.225 N/A N/A a.35.1 lambda repressor-like DNA-binding domains
View Download 0.221 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.219 N/A N/A a.112.1 Description not found.
View Download 0.210 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.208 N/A N/A d.93.1 SH2 domain

Predicted Domain #5
Region A:
Residues: [452-1026]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CGNKTVSVSS GMMKSPAISS AELFEGYDSL PERQMESPQK SKMKSPTLAS TDDINSASAS  60
   61 VNSHATSVKQ TELFVTDNSS KINDSVSAQS SVTTNFKDTF TTPMTSGMLN HENSERSFGS 120
  121 GLKLKITDSN LENMEDVEAK SANEFSTTPE DKHIHLANAA ELSALYDKYS TSPFGKSEAN 180
  181 SSPKPQKLEV KDRSKNENRS PYERYVGTSA ESKTFEIGNV RESKSTINTS LSSPLRVEDS 240
  241 RRSKNEDLGS LKEFEELSQK ISNMGMANIS SEALSDTAEN SSFVTDLNLN INNSSSVNLN 300
  301 EEQRVPDFGE ENVFDPDYME QNQMLETESR YTTDEFDFSD NQDAASSNYS NGQTNRTVTE 360
  361 TLSASDRNDK IPHSSLFTNL NQLTSNGGNY QDREDFSGDQ INKPQQSQPL HVKGPQTSSF 420
  421 GYRNSSANSS QPQAPYPVGR PLGKIRTGPL TVQPMQQGGN SSMYSFQSSQ HRFHSSQQRQ 480
  481 NQSLSFRNNT YGSGNNQNTF HPSPQLQQQP QNMRYLNNKL PINDRSPIPQ TQHHVPDGRP 540
  541 SLHINTTNRT NPLTAQSGFS QFMPPNSTST NPYSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [741-856]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NINNSSSVNL NEEQRVPDFG EENVFDPDYM EQNQMLETES RYTTDEFDFS DNQDAASSNY  60
   61 SNGQTNRTVT ETLSASDRND KIPHSSLFTN LNQLTSNGGN YQDREDFSGD QINKPQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [857-1026]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSQPLHVKGP QTSSFGYRNS SANSSQPQAP YPVGRPLGKI RTGPLTVQPM QQGGNSSMYS  60
   61 FQSSQHRFHS SQQRQNQSLS FRNNTYGSGN NQNTFHPSPQ LQQQPQNMRY LNNKLPINDR 120
  121 SPIPQTQHHV PDGRPSLHIN TTNRTNPLTA QSGFSQFMPP NSTSTNPYSS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle