YRC Public Data Repository - Protein Structure Prediction

Protein:	APS1
Organism:	Saccharomyces cerevisiae
Length:	156 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for APS1.

Description	E-value	Query Range	Subject Range
gi\|4741996 - gi\|4741996\|gb\|AAD28793.1\|AF146688_2 19 kDa Golgi adaptor protein adaptin [Takifugu rubripes] gi\|47230618 - gi\|47230618\|emb\|CAF99811.1\| unnamed protein product [Tetraodon nigroviridis]	8.0E-39	[4..155]	[1..150]
gi\|12005732 - gi\|12005732\|gb\|AAG44595.1\|AF251295_1 DC22 [Homo sapiens]	2.0E-38	[5..155]	[25..174]
gi\|11999126 - gi\|11999126\|gb\|AAG43051.1\|AF228054_1 clathrin-associated adaptor complex AP-1 small chain sigma1 [Dr...	7.0E-38	[3..153]	[1..149]
gi\|108711413, gi... - gi\|34897116\|ref\|NP_909904.1\| putative clathrin assembly protein [Oryza sativa], gi\|14718316\|gb\|AAK72... gi\|17149112 - gi\|17149112\|gb\|AAL35902.1\|AF443602_1 clathrin assembly protein AP19-like protein [Oryza sativa]	2.0E-37	[1..154]	[20..171]
gi\|1762309 - gi\|1762309\|gb\|AAB39510.1\| AP-1 Golgi-related complex component; clathrin coated vesicles; clathrin a...	3.0E-37	[3..154]	[1..150]
gi\|39593058, gi\|... - gi\|39593058\|emb\|CAE64527.1\| Hypothetical protein CBG09266 [Caenorhabditis briggsae], gi\|187031989\|em... aps-1 - clathrin coat assembly protein status:Confirmed UniProt:O16369 protein_id:AAB65902.1 gi\|157763874 - gi\|157763874\|ref\|XP_001674280.1\| Hypothetical protein CBG09266 [Caenorhabditis briggsae AF16]	4.0E-37	[3..152]	[1..148]
gi\|113931322, gi... - gi\|89268919\|emb\|CAJ82923.1\| adaptor-related protein complex 1, sigma 2 subunit [Xenopus tropicalis],... gi\|109511709, gi... - gi\|109511709\|ref\|XP_001068004.1\| PREDICTED: similar to AP-1 complex subunit sigma-2 (Adapter-related... gi\|109130007 - gi\|109130007\|ref\|XP_001102083.1\| PREDICTED: similar to AP-1 complex subunit sigma-2 (Adapter-related... tr\|F6SFB5\|F6SFB5... - AP-1 complex subunit sigma-2 OS=Homo sapiens GN=AP1S2 PE=4 SV=1 AP1S2_MOUSE - AP-1 complex subunit sigma-2 OS=Mus musculus GN=Ap1s2 PE=1 SV=1 gi\|542166448\|ref... - PREDICTED: AP-1 complex subunit sigma-2 isoform X1 [Zonotrichia albicollis] AP1S2_BOVIN - AP-1 complex subunit sigma-2 OS=Bos taurus GN=AP1S2 PE=2 SV=1	6.0E-37	[4..151]	[1..146]

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Predicted Domain #1

Region A:
Residues: [1-88]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQLKYLLLV SRQGKIRLKK WYTAMSAGEK AKIVKDLTPT ILARKPKMCN IIEYNDHKVV  60
   61 YKRYASLYFI VGMTPDVDNE LLTLEIIH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	297.165202
Match:	1gw5S_
Description:	Sigma2 adaptin (clathrin coat assembly protein AP17)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [89-156]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RFVETMDTYF GNVCELDIIF NFSKVYDILN EMIMCDGSIA ESSRKEVLHH VTVMDTMESN  60
   61 DNLERVLS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	297.165202
Match:	1gw5S_
Description:	Sigma2 adaptin (clathrin coat assembly protein AP17)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits