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View Structure Prediction Details

Protein: YLR149C
Organism: Saccharomyces cerevisiae
Length: 730 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR149C.

Description E-value Query
Range
Subject
Range
YLR149C - Putative protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutat...
YL149_YEAST - Uncharacterized protein YLR149C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLR149C ...
gi|151941311 - gi|151941311|gb|EDN59689.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..730] [1..730]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [14..585] [875..1473]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
0.0 [44..580] [829..1359]

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Predicted Domain #1
Region A:
Residues: [1-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIDGTGQSK EALQDERLNT GSDKVYQNYM MPALELYDAK VSINHWQLRD CIKPGSMNQS  60
   61 KLYYIYDHSI RVLDTDSSVL RSPVRRHNSI QPSNSGKNST EKTSTKGSRT TGSYISKNLH 120
  121 VPSEKLVEFN FKPRCFTELN GLTVCGGLIG SDDKGFPSNW NRLAQDANIS LPPPSQPINI 180
  181 SKNISFPINS HYSNPNIWKG IVEFYNQETD TMMTFTLGQF INNCVTLYDR ASMQFDLFAC 240
  241 NNDGHLYQCD VSNRDVTLVK RYADLKFPLN NASLSHDGQT MVVSGDSNKF AVYNQNELTN 300
  301 QFSLHYDNHP SWGSSVNRVR RIPRFALPDE SEYIENIYEA PNSDHGFYNS FSENDLQFAT 360
  361 VFQNGTCAIY DIRN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.145838346152539 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [375-533]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPMAEISS TRPHSHNGAF RVCRFSYGLD DLLFISEHQG RVHVVDTRNY VNHQVIVIPD  60
   61 KVNMEYINER KHNTNHNFTT NNNNENESND SKNELQGADY RSLSRRRFSL PSMPNVTTEP 120
  121 WITMAQRIPK KYLEPQILPF PKVMDKISNE SVLFSTKGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.69897
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.145838346152539 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [534-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSSDVAHPYK RRCSFRVRRV STSAPTADYS NNNVNASLGT PAADSIATSS SNSAPQNLID  60
   61 PLILSHQQAS NDVFEDDEYY EAYNDVHSTY RVSSDYHGVS ARAFESFLRP PSTPDLPSDD 120
  121 DNFAANSRNN RGTSNFLRRP VITTQESNEF SEENNISGID WVEDRNGSSL IIGTDYGIMR 180
  181 WNINSWARRS FSSYDLC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.271 a.74.1 Cyclin-like


YRC Informatics Platform - Version 3.0
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