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View Structure Prediction Details

Protein: YLR137W
Organism: Saccharomyces cerevisiae
Length: 367 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR137W.

Description E-value Query
Range
Subject
Range
RKM5_YEAS7 - Ribosomal lysine N-methyltransferase 5 OS=Saccharomyces cerevisiae (strain YJM789) GN=RKM5 PE=3 SV=1
YLR137W - Putative S-adenosylmethionine-dependent methyltransferase
RKM5_YEAS2 - Ribosomal lysine N-methyltransferase 5 OS=Saccharomyces cerevisiae (strain JAY291) GN=RKM5 PE=3 SV=1
RKM5_YEAST - Ribosomal lysine N-methyltransferase 5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=R...
RKM5_YEAS6 - Ribosomal lysine N-methyltransferase 5 OS=Saccharomyces cerevisiae (strain AWRI1631) GN=RKM5 PE=3 SV...
0.0 [1..367] [1..367]
SPCC4G3.16 - CMP /dCMP deaminase family
RIB2_SCHPO - Diaminohydroxyphosphoribosylamino-pyrimidine deaminase OS=Schizosaccharomyces pombe (strain 972 / AT...
2.0E-37 [71..207] [37..139]

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Predicted Domain #1
Region A:
Residues: [1-225]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAFKLWLLDE ETIYEHVFER YTQLEGQSGK LAQDLGIQDR RGGVLEITFE PSGLEGGRKK  60
   61 KRVRRRNKAS SVEEDQNVAV DSYHVSVGQS ISSLRSSRDN GNSTTGYVLW STTPFFINWL 120
  121 LYSTSAAPFR LGSQVEVTCG SSCEGHKLEL PRLVDLTGAD RGKRGILELG AGISGILPVI 180
  181 LGNFVDTYVS TDQKGILNKL KDNIMENLSQ LTRKRCISRS LRLEL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [226-367]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTVEPVGDAD ITAASLPSKS TLHLEVAALD WEKINLQDKK THSLHPELSL IGETCSSVYV  60
   61 IAMDVIYNEY LIDPFLKTLK QLKHWLQTTY NLQFHVLVGI HLRSQEVTTL FLEKAIIEYD 120
  121 FTVYDIVDQV IQESRFNFYL IT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.816 c.50.1 Macro domain-like
View Download 0.801 c.61.1 PRTase-like
View Download 0.677 d.79.5 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IspF
View Download 0.675 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.657 c.55.1 Actin-like ATPase domain
View Download 0.589 c.97.1 Cytidine deaminase-like
View Download 0.541 d.79.4 Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain
View Download 0.541 c.115.1 Hypothetical protein MTH777 (MT0777)
View Download 0.537 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.536 c.1.10 Aldolase
View Download 0.536 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.512 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.485 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.474 c.1.21 Dihydropteroate synthetase-like
View Download 0.467 c.55.1 Actin-like ATPase domain
View Download 0.457 c.23.10 SGHN hydrolase
View Download 0.457 b.60.1 Lipocalins
View Download 0.439 c.23.1 CheY-like
View Download 0.430 c.52.1 Restriction endonuclease-like
View Download 0.420 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.420 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.416 c.30.1 PreATP-grasp domain
View Download 0.408 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.408 c.3.1 FAD/NAD(P)-binding domain
View Download 0.403 b.60.1 Lipocalins
View Download 0.402 d.52.2 GMP synthetase C-terminal dimerisation domain
View Download 0.401 c.1.10 Aldolase
View Download 0.396 d.58.14 Ribosomal protein S6
View Download 0.396 c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.385 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.379 a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.373 d.79.1 YjgF-like
View Download 0.373 c.23.1 CheY-like
View Download 0.354 c.47.1 Thioredoxin-like
View Download 0.353 d.13.1 HIT-like
View Download 0.351 c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.346 c.13.2 Anti-sigma factor antagonist SpoIIaa
View Download 0.345 c.23.1 CheY-like
View Download 0.344 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.341 c.55.1 Actin-like ATPase domain
View Download 0.337 c.46.1 Rhodanese/Cell cycle control phosphatase
View Download 0.331 c.1.8 (Trans)glycosidases
View Download 0.331 c.1.17 Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain
View Download 0.326 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.324 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.323 c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.314 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.312 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.311 c.47.1 Thioredoxin-like
View Download 0.310 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.305 f.14.1 Voltage-gated potassium channels
View Download 0.303 b.60.1 Lipocalins
View Download 0.303 c.23.4 Succinyl-CoA synthetase domains
View Download 0.301 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.299 a.79.1 Antitermination factor NusB
View Download 0.295 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.293 c.32.1 Tubulin/Dihydroxyacetone kinase nucleotide-binding domain
View Download 0.289 b.60.1 Lipocalins
View Download 0.288 c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.287 c.1.12 Phosphoenolpyruvate/pyruvate domain
View Download 0.285 c.10.1 RNI-like
View Download 0.261 d.80.1 Tautomerase/MIF
View Download 0.259 c.17.1 Caspase-like
View Download 0.258 c.1.24 Pyridoxine 5'-phosphate synthase
View Download 0.258 c.23.6 Cobalamin (vitamin B12)-binding domain
View Download 0.255 c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.251 c.108.1 HAD-like
View Download 0.250 d.118.1 N-acetylmuramoyl-L-alanine amidase-like
View Download 0.245 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.240 d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.223 c.52.1 Restriction endonuclease-like
View Download 0.223 c.61.1 PRTase-like
View Download 0.223 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain
View Download 0.221 c.23.1 CheY-like
View Download 0.217 d.105.1 Clathrin adaptor appendage, alpha and beta chain-specific domain
View Download 0.215 f.1.1 Colicin
View Download 0.200 c.55.1 Actin-like ATPase domain


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