YRC Public Data Repository - Protein Structure Prediction

Protein:	SPC3
Organism:	Saccharomyces cerevisiae
Length:	184 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPC3.

Description	E-value	Query Range	Subject Range
SPC3_YEAST - Signal peptidase complex subunit SPC3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SP... gi\|207343142 - gi\|207343142\|gb\|EDZ70698.1\| YLR066Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190406104 - gi\|190406104\|gb\|EDV09371.1\| microsomal signal peptidase subunit 3 [Saccharomyces cerevisiae RM11-1a] SPC3 - Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-ter... gi\|151941234 - gi\|151941234\|gb\|EDN59612.1\| signal peptidase complex subunit [Saccharomyces cerevisiae YJM789]	2.0E-67	[1..184]	[1..184]
SPC3B_ARATH - Signal peptidase complex subunit 3B OS=Arabidopsis thaliana GN=At5g27430 PE=2 SV=1	7.0E-47	[1..165]	[1..150]
SPC3_SCHPO - Probable microsomal signal peptidase subunit 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843... spc3 - signal peptidase subunit Spc3	2.0E-44	[5..176]	[3..175]
SPCS3_CHICK - Signal peptidase complex subunit 3 OS=Gallus gallus GN=SPC22 PE=1 SV=1	8.0E-43	[12..172]	[8..164]
SPCS3_MOUSE - Signal peptidase complex subunit 3 OS=Mus musculus GN=Spcs3 PE=1 SV=1	8.0E-42	[1..173]	[1..165]
ENSCJAT00000010473 - null gi\|125988403, gi... - gi\|32766258\|gb\|AAH54817.1\| Signal peptidase complex subunit 3 homolog (S. cerevisiae) [Mus musculus]... SPCS3_BOVIN - Signal peptidase complex subunit 3 OS=Bos taurus GN=SPCS3 PE=2 SV=1 tr\|U3KPB2\|U3KPB2... - Uncharacterized protein OS=Oryctolagus cuniculus GN=SPCS3 PE=4 SV=1 SPCS3 - signal peptidase complex subunit 3 homolog (S. cerevisiae) SPCS3_CANLF - Signal peptidase complex subunit 3 OS=Canis lupus familiaris GN=SPCS3 PE=1 SV=1	1.0E-41	[13..172]	[2..164]
SP22_ORYSA, SPCS... - (Q9LGB4) Probable signal peptidase complex subunit 3 (EC 3.4.-.-) (Microsomal signal peptidase 22 kD... gi\|222617680, gi... - ref\|NP_909137.1\| unnamed protein product [Oryza sativa (japonica cultivar-group)], gi\|222617680\|gb\|... gi\|218187454 - gi\|218187454\|gb\|EEC69881.1\| hypothetical protein OsI_00256 [Oryza sativa Indica Group]	4.0E-38	[1..165]	[1..150]
CE00269 - Signal peptidase status:Confirmed UniProt:P34525 protein_id:AAA28096.1	8.0E-35	[1..169]	[1..161]

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Predicted Domain #1

Region A:
Residues: [1-184]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSFVQRFQN VSNQAFSMGI VMVVFIMASS YYQLINNNAF SVPSNIDNVK TLINVRTSRY  60
   61 FGSQRGKAKE NMKIKFDLNT DLTPLFNWNT KQVFVYLTAE YNSTEKITSE VTFWDKIIKS 120
  121 KDDAVIDVND LRSKYSIWDI EDGKFEGKDL VFKLHWNVQP WVGLLTYGET VGNYTLTVEN 180
  181 KNKV

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits