YRC Public Data Repository - Protein Structure Prediction

Protein:	COX12
Organism:	Saccharomyces cerevisiae
Length:	83 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COX12.

Description	E-value	Query Range	Subject Range
gi\|108708561, gi... - gi\|9967277\|dbj\|BAB12338.1\| cytochrome c oxidase subunit 6b [Oryza sativa Japonica Group], gi\|5092088...	2.0E-32	[3..80]	[92..169]
gi\|7269660, gi\|7... - pir\|\|T02907 hypothetical protein T13J8.170 - Arabidopsis thaliana, gi\|7269660\|emb\|CAB79608.1\| putat...	2.0E-30	[4..80]	[82..164]
CX6B1_BOVIN - Cytochrome c oxidase subunit 6B1 OS=Bos taurus GN=COX6B1 PE=1 SV=2	2.0E-30	[1..80]	[1..86]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	7.0E-30	[2..80]	[1..85]
CX6B1_MOUSE - Cytochrome c oxidase subunit 6B1 OS=Mus musculus GN=Cox6b1 PE=1 SV=2 gi\|109467443, gi... - gi\|223718723\|ref\|NP_001138745.1\| cytochrome c oxidase, subunit VIb polypeptide 1 [Rattus norvegicus]...	8.0E-30	[1..80]	[1..86]
gi\|114676756 - gi\|114676756\|ref\|XP_001160605.1\| PREDICTED: hypothetical protein [Pan troglodytes] gi\|123996805, gi... - gi\|60655227\|gb\|AAX32177.1\| cytochrome c oxidase subunit VIb [synthetic construct], gi\|123996805\|gb\|A... COX6B1 - cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)	2.0E-29	[1..80]	[1..86]
COX12 - Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membran... gi\|190406078 - gi\|190406078\|gb\|EDV09345.1\| cytochrome c oxidase subunit VIb [Saccharomyces cerevisiae RM11-1a] ORFP:14686 - YLR038C, Contig c49 12485-12736 gi\|151941207 - gi\|151941207\|gb\|EDN59585.1\| cytochrome c oxidase subunit VIb [Saccharomyces cerevisiae YJM789] COX12_YEAST - Cytochrome c oxidase subunit 6B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=COX12 PE...	3.0E-29	[1..83]	[1..83]

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Predicted Domain #1

Region A:
Residues: [1-83]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADQENSPLH TVGFDARFPQ QNQTKHCWQS YVDYHKCVNM KGEDFAPCKV FWKTYNALCP  60
   61 LDWIEKWDDQ REKGIFAGDI NSD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	187.512579
Match:	1occH_
Description:	Cytochrome c oxidase subunit h
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytochrome-c oxidase activity	4.43411953394546	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	4.43411953394546	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	4.43411953394546	bayes_pls_golite062009
heme-copper terminal oxidase activity	4.19888886424808	bayes_pls_golite062009
oxidoreductase activity	0.981765859404114	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: