YRC Public Data Repository - Protein Structure Prediction

Protein:	IZH3
Organism:	Saccharomyces cerevisiae
Length:	543 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for IZH3.

Description	E-value	Query Range	Subject Range
CG5315-PA, CG531... - This gene is referred to in FlyBase by the symbol Dmel\CG5315 (CG5315, FBgn0038984). It is a protein... gi\|220953776, gi... - gi\|220953776\|gb\|ACL89431.1\| CG5315-PA [synthetic construct], gi\|220943902\|gb\|ACL84494.1\| CG5315-PA [...	397.0	[0..153]	[543..88]
gi\|54637593, gi\|... - gi\|54637593\|gb\|EAL26995.1\| GA18798-PA [Drosophila pseudoobscura], gi\|125773203\|ref\|XP_001357860.1\| G...	389.0	[0..153]	[543..83]
gi\|77404219, gi\|... - gi\|77404219\|ref\|NP_001029227.1\| adiponectin receptor 1 [Bos taurus], gi\|74354768\|gb\|AAI02260.1\| Adip...	370.0	[0..122]	[540..19]
ADR1_MOUSE - Adiponectin receptor protein 1 OS=Mus musculus GN=Adipor1 PE=1 SV=1	363.0	[0..167]	[540..49]
gi\|50261269, gi\|... - gi\|55742864\|ref\|NP_001007194.1\| adiponectin receptor 1 [Sus scrofa], gi\|50261269\|gb\|AAT72305.1\| adip... gi\|55742864 - ref\|NP_001007194.1\| adiponectin receptor 1 [Sus scrofa]	362.0	[0..167]	[540..49]
gi\|71895887, gi\|... - gi\|71895887\|ref\|NP_001026198.1\| adiponectin receptor 1 [Gallus gallus], gi\|67782277\|gb\|AAY81969.1\| a...	361.0	[0..185]	[540..67]
ADIPOR1 - adiponectin receptor 1 gi\|55589076, gi\|... - gi\|55589076\|ref\|XP_514107.1\| PREDICTED: adiponectin receptor 1 isoform 7 [Pan troglodytes], gi\|11457...	361.0	[0..167]	[540..49]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMDSSSKSLT QYIPSPMGSL SRLKQKGVDN FQKVKKSGKS IYNYNYSKFV PHPFSTIDES  60
   61 VKHSESGRYD DLEIIRPTKE KEVTSSVYKR NSGKSLNTES QFSLGDSDAA TLVNSVATFK 120
  121 LNNASTSTSL VSSSSTVCSQ AKSSLRSPTS RLNDTKIKEE NNYISSVKDY CGPM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [175-543]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKSMVKTEIL IEEPLNPTTD IKSFINSYNH GKAYSLGETQ HLHYYQLPFP WRENRYIIHG  60
   61 YRFYNTHSKS LLSIFNWYGW HNETSNIWSH LLGAIYIIYL AIYDFPQSEV WRNSQVPPQA 120
  121 RWIVFMFLAA ALKCMLSSVF WHTFNGTSFL KLRSKFACVD YSGITILITA SILTTEFVTM 180
  181 YSCYWAMYTY MSISLALGVF GVFMNWSPRF DRPEARPLRI RFFILLATMG VLSFLHLIFL 240
  241 TDLHYAATLF SPVTYKSVVW YLVGVVFYGS FIPERFRSDV QVDKTIPTNY ELSTDLEIIT 300
  301 KQREIHFREV PTAHSKCSSC PSHAKSFKSL WWVDYFGCSH TFWHFFVVLG VIGHYRAILD 360
  361 MFAKRWILS

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	117.113509
Match:	PF03006
Description:	Haemolysin-III related

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits