YRC Public Data Repository - Protein Structure Prediction

Protein:	MEU1
Organism:	Saccharomyces cerevisiae
Length:	337 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MEU1.

Description	E-value	Query Range	Subject Range
gi\|975224 - gi\|975224\|emb\|CAA62156.1\| orf [Saccharomyces cerevisiae]	0.0	[1..337]	[1..337]
PUNA_GEOSE - Purine nucleoside phosphorylase 1 OS=Geobacillus stearothermophilus GN=punA PE=1 SV=1	7.0E-88	[11..295]	[3..274]
MTAP_MOUSE - S-methyl-5'-thioadenosine phosphorylase OS=Mus musculus GN=Mtap PE=1 SV=1	7.0E-88	[33..320]	[10..283]
gi\|93278657, gi\|... - gi\|93278662\|pdb\|2A8Y\|L Chain L, Crystal Structure Of 5'-Deoxy-5'methylthioadenosine Phosphorylase Co... MTAP_SULSO - S-methyl-5'-thioadenosine phosphorylase OS=Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / J...	8.0E-88	[30..315]	[5..270]
gi\|15621483, gi\|... - gi\|15920700\|ref\|NP_376369.1\| 5'-methylthioadenosine phosphorylase II [Sulfolobus tokodaii str. 7], g...	2.0E-86	[30..315]	[6..271]
gi\|38570318, gi\|... - gi\|38570318\|gb\|AAR24607.2\| methylthioadenosine phosphorylase [Homo sapiens], gi\|11602392\|gb\|AAG38871...	2.0E-86	[33..317]	[10..281]
gi\|2624420, gi\|1... - gi\|2624420\|pdb\|1VFN\| Chain , Purine Nucleoside Phosphorylase, gi\|157834116\|pdb\|1VFN\|A Chain A, Pur...	5.0E-86	[21..293]	[10..280]

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Predicted Domain #1

Region A:
Residues: [1-337]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRIKNTFSV AKRLKLSKVM TNSELPSIFE GTVDLGIIGG TGLYNLDCLE PIALLPPMVT  60
   61 PWGTTSSPVT ISQFVGTNSH FHVAFIARHG INHEYPPTKV PFRANMAALK NLNCKAVLSF 120
  121 SAVGSLQPHI KPRDFVLPQQ IIDRTKGIRH SSYFNDEGLV GHVGFGQPFS QKFAEYIYQF 180
  181 KNEITNPESE EPCHLHYDKD MTVVCMEGPQ FSTRAESKMY RMFGGHVINM SVIPEAKLAR 240
  241 ECELPYQMIC MSTDYDAWRD EAEPVTVETV IGNLTNNGRN ANILASKIIV SMAKEIPEFM 300
  301 HTGDGLRGSI KKSISTKPEA MSKETLERLR YLFPNYW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	438.491979
Match:	1cb0A_
Description:	5'-deoxy-5'-methylthioadenosine phosphorylase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits