YRC Public Data Repository - Protein Structure Prediction

Protein:	YLR001C
Organism:	Saccharomyces cerevisiae
Length:	862 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR001C.

Description	E-value	Query Range	Subject Range
YL001_YEAST - FAS1 domain-containing protein YLR001C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=Y... YLR001C - Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purifi...	0.0	[1..862]	[1..862]
gi\|13940365 - gi\|13940365\|emb\|CAC38012.1\| hypothetical protein [Zygosaccharomyces rouxii]	0.0	[10..779]	[2..774]
TGFBI - transforming growth factor, beta-induced, 68kDa gi\|114601810, gi... - gi\|114601814\|ref\|XP_001169327.1\| PREDICTED: transforming growth factor, beta-induced, 68kDa isoform ... gi\|157928390, gi... - gi\|60655449\|gb\|AAX32288.1\| transforming growth factor beta-induced [synthetic construct], gi\|6065544...	0.0	[22..653]	[86..675]
gi\|2116676 - gi\|2116676\|dbj\|BAA20089.1\| RGD-containing collagen associated protein [Porcine rotavirus] BGH3_PIG - Transforming growth factor-beta-induced protein ig-h3 OS=Sus scrofa GN=TGFBI PE=1 SV=1	0.0	[22..655]	[86..677]
BGH3_MOUSE - Transforming growth factor-beta-induced protein ig-h3 OS=Mus musculus GN=Tgfbi PE=1 SV=1	0.0	[22..655]	[86..677]
gi\|1518107 - gi\|1518107\|gb\|AAB07015.1\| transforming growth factor induced protein	0.0	[22..655]	[85..676]
gi\|2257601, gi\|4... - gi\|45384294\|ref\|NP_990367.1\| transforming growth factor, beta-induced, 68kDa [Gallus gallus], gi\|225...	0.0	[22..655]	[79..669]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[37..631]	[101..653]

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Predicted Domain #1

Region A:
Residues: [1-197]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMAIQTIKY IFWLLPILGL TQALLQNPGD DFPFSTVIDI LSENVEFSTF LRIIQKTGHV  60
   61 QYLNELQNFT LFAPINSAFI KGDQTTDQFE EHFHIEDFLI HDRVLQVRDL ENGTYLEKRA 120
  121 AKAPLLLRKH ERHCFVNEIA VVEPDLLPSF QNASLQGINN LLLIQPQINE LLVQLDEETQ 180
  181 DLKIFSDFIS SFSNYNA

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	2.244125
Match:	PF02469
Description:	Fasciclin domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	0.437329334769699	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [198-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YTNSSTVLVP LDVNFRKFFN TIEINYLLDK YNKLGKSNTI SQAKWAADRT SLLQELIIDD  60
   61 VYGGILPKEL ILENKNNRKL FMKSN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [283-661]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEGTSVSVNN SDYSPISNRI FEIGVVHGFS DLDFLRTHIQ FDAEKYLHGL NCSEFVKELY  60
   61 FRDLEKFIQN GRKITIFVPQ ASFNEDRGYT KPSLLYHFVE GKIDLEQDFS SLRPIQYAPT 120
  121 QIYDSAFCSS AKRLGGHCQK FKITRSNKGY YINGRFKILN TKPYEIGNTS IYSIDDDLQL 180
  181 PGDLVLSLAP ENHCSISLML LKELNLLDLP SNHKGYTILL PCMNSWDNND LTIDYLRSNK 240
  241 TALNLLMRNL IFEDLIYSNN YSISTTVKNL YGNSVSIGVQ KIVGSQNLTK ISVSTIKESI 300
  301 IIEESSDIFF NQGVIHPIDQ LDFPVDLEIS LKELIETTGT KEIFDFFNLF YDLSSIIWNN 360
  361 EEYSLLVPTA SSIPLSGIT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [662-801]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANSTNLRKFL ELHLIPANVT QNLLDCNGSI STKLGTKLNC RKDHLDNVFV SIQGDWTKEV  60
   61 RVLKTGCTTN LKSSCIFLID KPISLSWLNS EKYHLRLPGI AVGFGVIIGV TIAISLLFCI 120
  121 IITRGGKVKD KNQRGRNDRA

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5

Region A:
Residues: [802-862]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTPLIQHSPI IHNPSYSATA HLSPLSQPTF EGSYSVNAIQ TPRDIRRVGS DQKGGRSVST  60
   61 S

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: