| Protein: | TPO1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 586 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPO1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..586] | [1..586] |
|
|
0.0 | [9..584] | [41..607] |
|
|
1.0E-94 | [24..583] | [1..573] |
|
Region A: Residues: [1-119] |
1 11 21 31 41 51
| | | | | |
1 MSDHSPISNK ENHLLPSDSS RSSSSDMHST GTTGTTGVEP VDFTGEGAKY TTATEGNGGA 60
61 DLAIQRTTTM NSAAESEVNI TRRLTKILTG SVNEPDRVEV DYTNCAPMGG DRPYPPSLP
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.688 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.530 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.407 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.688 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.530 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.428 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.413 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.407 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.356 | d.80.1 | Tautomerase/MIF |
| View | Download | 0.307 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.304 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.303 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.295 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.285 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.275 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.274 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.235 | d.108.1 | Acyl-CoA N-acyltransferases (Nat) |
| View | Download | 0.225 | c.95.1 | Thiolase-like |
| View | Download | 0.220 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.218 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.209 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.205 | d.58.9 | RuBisCO, large subunit, small (N-terminal) domain |
| View | Download | 0.200 | c.23.5 | Flavoproteins |
|
Region A: Residues: [120-323] |
1 11 21 31 41 51
| | | | | |
1 SRDLYEVTFD GPNDPLHPFN WPMKKKVLLC LVLCLDSIAI AMCSSIFASA VPQICEIYHV 60
61 IEVVAILGIT LFVLGFAASP VIYAPLSELY GRKGVLVLSA FGFALFQFAV ATAENLQTIF 120
121 ICRFFGGFIG AAPMAVVPAA FADMFDTNVR GKAIALFSLG VFVGPILSPV MGSYIAQRTT 180
181 WRWLEYVVGC FASAVFVAIV LFFE
|
|
Region B: Residues: [365-586] |
1 11 21 31 41 51
| | | | | |
1 TVTRPIIMLF VEPLLLFVTI YNSFVYGILY LLLEAYPLVF VEGYGFTENG ELPYIALIIG 60
61 MMVCAAFIWY MDNDYLKRCR AKGKLVPEAR LYAMVIAGTV FPIGILWFCW TGYYPHKIHW 120
121 MVPTVGGAFI GFGLMGIFLP CLNYIIESYL LLAASAVAAN TFMRSAFGAC FPLFAGYMFR 180
181 GMGIGWAGLL LGLFAAAMIP VPLLFLKYGE SIRKKSKYAY AA
|
| Detection Method: | |
| Confidence: | 19.30103 |
| Match: | 1ja5A_ |
| Description: | No description for 1ja5A_ was found. |
| Term | Confidence | Notes |
| transporter activity | 4.09176719149278 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.59744164024479 | bayes_pls_golite062009 |
| transmembrane transporter activity | 3.5865018981083 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 3.54194478414824 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.21266150105753 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 1.79369588808394 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 1.59419818573076 | bayes_pls_golite062009 |
| organic acid transmembrane transporter activity | 1.24937104052238 | bayes_pls_golite062009 |
| secondary active transmembrane transporter activity | 1.22264637452409 | bayes_pls_golite062009 |
| binding | 1.01584233411372 | bayes_pls_golite062009 |
| alcohol transmembrane transporter activity | 0.924836669821548 | bayes_pls_golite062009 |
| polyol transmembrane transporter activity | 0.924836669821548 | bayes_pls_golite062009 |
| glycerol transmembrane transporter activity | 0.812001619402678 | bayes_pls_golite062009 |
| symporter activity | 0.74591237387473 | bayes_pls_golite062009 |
| solute:cation symporter activity | 0.74591237387473 | bayes_pls_golite062009 |
| cation:sugar symporter activity | 0.143419068761182 | bayes_pls_golite062009 |
| sugar:hydrogen symporter activity | 0.143419068761182 | bayes_pls_golite062009 |
|
Region A: Residues: [324-364] |
1 11 21 31 41 51
| | | | | |
1 ETHHPTILVN KAKQMRKQSN NWGIHAAHED VELSIKDIVQ K
|
| Detection Method: | |
| Confidence: | 19.30103 |
| Match: | 1ja5A_ |
| Description: | No description for 1ja5A_ was found. |
