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View Structure Prediction Details

Protein: YLL007C
Organism: Saccharomyces cerevisiae
Length: 665 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLL007C.

Description E-value Query
Range
Subject
Range
YL007_YEAST - Uncharacterized protein YLL007C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YLL007C ...
YLL007C - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th...
0.0 [1..665] [1..665]

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Predicted Domain #1
Region A:
Residues: [1-115]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKHNRQMPDE SLENIKVLLN PKLGKPVKSL TSAQSKACYH TLISNKNLNK TSDEYEKLLA  60
   61 NYILLCDEKY LCKTVIPDSR FWAILCDNCQ KLRSETLVAN LIRIFNVALK CQDSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.360 d.41.4 Ribosomal protein L10e
View Download 0.452 f.14.1 Voltage-gated potassium channels
View Download 0.394 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.544 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.441 d.56.1 GroEL-intermediate domain like
View Download 0.350 d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.341 b.88.1 Mss4-like
View Download 0.339 f.14.1 Voltage-gated potassium channels
View Download 0.337 c.55.3 Ribonuclease H-like
View Download 0.312 a.77.1 DEATH domain
View Download 0.304 a.74.1 Cyclin-like
View Download 0.302 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.300 a.26.1 4-helical cytokines
View Download 0.297 a.4.12 TrpR-like
View Download 0.294 a.74.1 Cyclin-like
View Download 0.293 a.4.12 TrpR-like
View Download 0.293 d.94.1 HPr-like
View Download 0.266 a.118.15 Aconitase B, N-terminal domain
View Download 0.263 a.24.9 alpha-catenin/vinculin
View Download 0.262 a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.255 a.4.12 TrpR-like
View Download 0.237 a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.237 a.1.1 Globin-like
View Download 0.237 d.58.13 Anticodon-binding domain of PheRS
View Download 0.236 a.29.2 Bromodomain
View Download 0.225 d.232.1 Mago nashi protein
View Download 0.213 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.210 a.24.3 Cytochromes
View Download 0.209 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.206 d.58.16 Poly(A) polymerase, C-terminal domain
View Download 0.203 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.201 a.24.16 Nucleotidyltransferase substrate binding subunit/domain

Predicted Domain #2
Region A:
Residues: [116-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNEVIVSICH ISRENSQLIG ILLQLLSQRP IHIPLFTDTI LCITLFLKCS LTLCETSLSH  60
   61 AVEFVPRILI LLFQYNFPAS MSELLYIEDL QPLILEEFVP LKQRLINFLS SVSIDDYSCS 120
  121 LKADLLTAIK DNSVFQKGLE MEMGDLPSIN LLNAYDTFTF LNSPNGSFKR LYTEQLLFGE 180
  181 NDFPLYE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [355-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LRFWIESLAK SQSDLVSLLN LAIITLKYVC LSSSDLEAAI QTKSLLKTQV VALDSMRYKF  60
   61 ARTLQLDSIK KEQYRTWSSS IASFDTMLSG QVRDYVRHQR LLQLQKGTWV YAENPLN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.59
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [303-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIFKLSDQFR RLFNLSGKKE NQYSDSERDL KLQIATAVLN RQTCFYKTLE LF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.59
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [472-665]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEAGTPKVYF LIVSDNHANL LAREFETQTN DLPYLFDNKI LTSPGSEALA NGRTKVVVLK  60
   61 HITSFKSIEL TTPSRRTSSN VYIKLDEANV YTGVELKDRN DRTVLKFYLD TEEGRYIWLD 120
  121 GLKLISPFQH EDISEDTKEQ IDTLFDLRKN VQMINLNVRQ DIIVPPPEPS DEDEDEEFYN 180
  181 LETLKKVTQN FYFD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.373 b.60.1 Lipocalins
View Download 0.495 b.29.1 Concanavalin A-like lectins/glucanases
View Download 0.434 c.1.2 Ribulose-phoshate binding barrel
View Download 0.439 c.1.6 PLP-binding barrel
View Download 0.365 b.60.1 Lipocalins
View Download 0.346 c.1.11 Enolase C-terminal domain-like
View Download 0.342 d.19.1 MHC antigen-recognition domain
View Download 0.341 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.329 d.19.1 MHC antigen-recognition domain
View Download 0.321 d.157.1 Metallo-hydrolase/oxidoreductase
View Download 0.315 d.220.1 Metal cation-transporting ATPase, ATP-binding domain N
View Download 0.280 b.60.1 Lipocalins
View Download 0.264 b.60.1 Lipocalins
View Download 0.257 c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.247 f.13.1 Family A G protein-coupled receptor-like
View Download 0.244 b.78.1 alpha-D-mannose-specific plant lectins
View Download 0.237 d.142.1 Glutathione synthetase ATP-binding domain-like
View Download 0.206 b.68.4 TolB, C-terminal domain

Predicted functions:

Term Confidence Notes
binding 1.14406613230923 bayes_pls_golite062009
protein binding 0.749738289794699 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle