YRC Public Data Repository - Protein Structure Prediction

Protein:	YSR3
Organism:	Saccharomyces cerevisiae
Length:	404 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YSR3.

Description	E-value	Query Range	Subject Range
DS1P1_YEAST - Dihydrosphingosine 1-phosphate phosphatase LCB3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S2... LCB3 - Long-chain base-1-phosphate phosphatase with specificity for dihydrosphingosine-1-phosphate, regulat... gi\|207344105 - gi\|207344105\|gb\|EDZ71354.1\| YJL134Wp-like protein [Saccharomyces cerevisiae AWRI1631] gi\|190409371 - gi\|190409371\|gb\|EDV12636.1\| dihydrosphingosine-1-phosphate phophatase [Saccharomyces cerevisiae RM11...	344.0	[0..30]	[403..29]
SPAC823.11 - sphingosine-1-phosphate phosphatase DS1PP_SCHPO - Dihydrosphingosine 1-phosphate phosphatase C823.11 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2...	282.0	[0..23]	[398..11]
gi\|49527893, gi\|... - gi\|50292297\|ref\|XP_448581.1\| unnamed protein product [Candida glabrata], gi\|49527893\|emb\|CAG61544.1\|... gi\|49527893 - gi\|49527893\|emb\|CAG61544.1\| unnamed protein product [Candida glabrata]	273.0	[0..24]	[403..22]
gi\|55640905 - gi\|55640905\|ref\|XP_522876.1\| PREDICTED: sphingosine-1-phosphatase [Pan troglodytes]	270.0	[0..75]	[403..124]
SGPP1 - sphingosine-1-phosphate phosphatase 1	270.0	[0..75]	[403..124]
gi\|73964194 - gi\|73964194\|ref\|XP_547850.2\| PREDICTED: similar to sphingosine-1-phosphatase [Canis familiaris]	265.0	[0..75]	[403..128]
gi\|109478366 - gi\|109478366\|ref\|XP_343082.3\| PREDICTED: similar to Sphingosine-1-phosphate phosphatase 1 (Sphingosi...	257.0	[0..73]	[403..210]
gi\|76677311, gi\|... - gi\|76677311\|ref\|XP_595039.2\| PREDICTED: similar to sphingosine-1-phosphatase [Bos taurus], gi\|118150...	254.0	[0..75]	[403..128]

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Predicted Domain #1

Region A:
Residues: [1-89]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIIQTVTEL GVTEDTIKVQ MAPSGGKHLL ADPGNHPAEH FESQMSWLRF QTRQYLTRFT  60
   61 DNQSDFVHSL QKKHRTPFRD VYFKYTSLM

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [90-266]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSHMFYVIVL PMPVWLGYRD LTRDMIYVLG YSIYLSGYLK DYWCLPRPKS PPVDRITLSE  60
   61 YTTKEYGAPS SHSANATAVS LLFFWRICLS DTLVWPTKLL LLSLVIFYYL TLVFGRVYCG 120
  121 MHGMLDLFSG AAVGAICFFI RIWVVHALRN FQIGEHLWFP LLSVAWGLFI LFNHVRP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	16.39794
Match:	1d2tA
Description:	Bacterial acid phosphatase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [267-404]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IDECPCFEDS VAFIGVVSGL DCSDWLTERY GWNLVCSRYA SCGSKVFLRP LVGVASVIVW  60
   61 KDVISKTAVY TLLIKLLRFH DDRSEKVHFH NETSEEEECL LYSGVSKVEI VGRFLIYAGI 120
  121 PTTVFLLCPV FFTWTNLR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.838	a.74.1	Cyclin-like

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits