YRC Public Data Repository - Protein Structure Prediction

Protein:	TRK2
Organism:	Saccharomyces cerevisiae
Length:	889 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRK2.

Description	E-value	Query Range	Subject Range
TRK2_YEAST - Low-affinity potassium transport protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN... TRK2 - Component of the Trk1p-Trk2p potassium transport system	0.0	[1..889]	[1..889]
gi\|4809179 - gi\|4809179\|gb\|AAD30128.1\|AF136181_1 potassium transporter [Kluyveromyces lactis]	0.0	[6..875]	[4..880]
gi\|18699011 - gi\|18699011\|gb\|AAL77222.1\| potassium transporter [Podospora anserina]	0.0	[38..876]	[42..862]
trk1 - potassium ion transporter Trk1 TRK1_SCHPO - Potassium transport protein 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=trk1 PE=3 SV...	0.0	[37..856]	[1..826]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[58..856]	[16..818]
gi\|85084587 - gi\|85084587\|ref\|XP_957340.1\| hypothetical protein NCU06449 [Neurospora crassa OR74A] gi\|28918430, gi\|... - gi\|3724137\|emb\|CAA08813.1\| trk-1 [Neurospora crassa], gi\|32411647\|ref\|XP_326304.1\| hypothetical prot...	0.0	[34..863]	[15..790]
TRK1_SACUV - High-affinity potassium transport protein OS=Saccharomyces uvarum GN=TRK1 PE=3 SV=1 gi\|101498 - gi\|101498\|pir\|\|JU0466 potassium transport protein TRK1, high-affinity - yeast (Saccharomyces cerevi... TRK1_SACBA - High-affinity potassium transport protein OS=Saccharomyces bayanus GN=TRK1 PE=3 SV=1	0.0	[132..874]	[465..1213]
gi\|7799615 - gi\|7799615\|emb\|CAB91046.1\| high-affinity potassium uptake transporter [Debaryomyces occidentalis]	0.0	[163..860]	[325..953]
gi\|8099700 - gi\|8099700\|gb\|AAF72203.1\|AF267125_1 potassium transporter Trk1p [Candida albicans]	0.0	[152..860]	[373..996]

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Predicted Domain #1

Region A:
Residues: [1-95]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTAKRTSSR ASLALPFQLR LVHKKSWGHR LRDFISGFLK SCRPIAKYVF PNFIVVHYIY  60
   61 LITLSIIGSI LLYPCKNTAF IDVLFLAAGA STQGG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [96-354]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LATKSTNDFN LYQQIVVYVI TLLSTPILIH GFLAFVRLYW FERYFDNIRD ISKQNFKLRR  60
   61 TMTLQQRELS GSSGNAARSR SFKDNLFRGK FVSREDPRQS ASDVPMDSPD TSALSSISPL 120
  121 NVSSSKEESS DTQSSPPNFS SKRQPSDVDP RDIYKSIMML QKQQEKSNAN STDSFSSETN 180
  181 GPAFIVQERH ERRAPHCSLK RHSVLPSSQE LNKLAQTKSF QKLLGLRRDE GDHDYFDGAP 240
  241 HKYMVTKKKK ISRTQSCNI

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [355-889]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PTYTASPSPK TSGQVVENHR NLAKSAPSSF VDEEMSFSPQ ESLNLQFQAH PPKPKRREGD  60
   61 IGHPFTRTMS TNYLSWQPTF GRNSVFIGLT KQQKEELGGV EYRALRLLCC ILMVYYIGFN 120
  121 ILAFVTIVPW ACTRHHYSEI IRRNGVSPTW WGFFTAMSAF SNLGLSLTAD SMVSFDTAPY 180
  181 PLIFMMFFII IGNTGFPIML RFIIWIMFKT SRDLSQFKES LGFLLDHPRR CFTLLFPSGP 240
  241 TWWLFTTLVV LNATDWILFI ILDFNSAVVR QVAKGYRALM GLFQSVCTRT AGFNVVDLSK 300
  301 LHPSIQVSYM LMMYVSVLPL AISIRRTNVY EEQSLGLYDS GQDDENITHE DDIKETDHDG 360
  361 ESEERDTVST KSKPKKQSPK SFVGAHLRRQ LSFDLWYLFL GLFIICICEG RKIEDVNKPD 420
  421 FNVFAILFEV VSAYGTVGLS LGYPNTNTSL SAQFTVLSKL VIIAMLIRGR NRGLPYTLDR 480
  481 AIMLPSDKLE QIDRLQDMKA KGKLLAKVGE DPMTTYVKKR SHKLKKIATK FWGKH

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	189.823909
Match:	PF02386
Description:	Cation transport protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4

Region A:
Residues: [659-889]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQVSYMLMMY VSVLPLAISI RRTNVYEEQS LGLYDSGQDD ENITHEDDIK ETDHDGESEE  60
   61 RDTVSTKSKP KKQSPKSFVG AHLRRQLSFD LWYLFLGLFI ICICEGRKIE DVNKPDFNVF 120
  121 AILFEVVSAY GTVGLSLGYP NTNTSLSAQF TVLSKLVIIA MLIRGRNRGL PYTLDRAIML 180
  181 PSDKLEQIDR LQDMKAKGKL LAKVGEDPMT TYVKKRSHKL KKIATKFWGK H

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits