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View Structure Prediction Details

Protein: YKR018C
Organism: Saccharomyces cerevisiae
Length: 725 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKR018C.

Description E-value Query
Range
Subject
Range
YKR18_YEAST - Mitochondrial outer membrane protein YKR018C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
YKR018C - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th...
0.0 [1..725] [1..725]
TT39B_MACFA - Tetratricopeptide repeat protein 39B OS=Macaca fascicularis GN=TTC39B PE=2 SV=1
0.0 [123..718] [114..623]
gi|2865252 - gi|2865252|gb|AAC39582.1| unknown [Homo sapiens]
0.0 [119..725] [45..561]
SPAC11E3.14 - conserved protein
YDYE_SCHPO - Uncharacterized protein C11E3.14 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC11E3....
0.0 [118..723] [54..586]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-99 [323..707] [1..346]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKVFGFGAK EEIPELSQEE KTKAILKQAH DFEQALRAMD YVLDDNADEG LALLDESDAK  60
   61 EASDQTINAL ARGVIEFLEA TLGFEAEEMK KASATLAKAE ALSLKSRERA QKIGLKSSSL 120
  121 YPPGTVYAVT YTESCLLHAL LMIFSESMME AAKAILKLRK SYYMLQEILE TIKAANKAKK 180
  181 LKI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.550 0.206 cytoplasm a.24.9 alpha-catenin/vinculin
View Download 0.379 0.001 nucleus c.92.2 "Helical backbone" metal receptor
View Download 0.399 0.000 nucleus a.19.1 Fertilization protein
View Download 0.430 0.000 nucleus a.63.1 Apolipophorin-III
View Download 0.627 0.000 nucleus f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.374 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.358 N/A N/A a.47.1 STAT
View Download 0.300 N/A N/A a.74.1 Cyclin-like
View Download 0.287 N/A N/A b.55.1 PH domain-like
View Download 0.241 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.232 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.225 N/A N/A a.47.2 t-snare proteins
View Download 0.222 N/A N/A f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.220 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.215 N/A N/A a.7.8 GAT domain
View Download 0.212 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.211 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.209 N/A N/A f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.206 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.205 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.204 N/A N/A a.149.1 RNase III endonuclease catalytic domain
View Download 0.204 N/A N/A a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.201 N/A N/A a.123.1 Nuclear receptor ligand-binding domain
View Download 0.201 N/A N/A b.40.4 Nucleic acid-binding proteins

Predicted Domain #2
Region A:
Residues: [184-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSGSEDKEST PATFITGGDA FNSVDIPYEL TPEEQKDKDL LQFAEQIHSM RTERLSGAHI  60
   61 GNSPAINRLR GELGLQAMED LPEEEITDHK VLSDDIDLSQ ATIDEFVHSG VNLCFGILQV 120
  121 VISLLPPAIG AVLSVVGFRG SREEGLRLVW KATKQRNVHG CIGLLALMFY YDGPFQFTDD 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [364-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFDIPAAVKD SSNSEDSEDE EMDGPTLLHP GKILEDALLQ SRALFPNSAL WLLNEARMLS  60
   61 GKGRLEEAVA LMDSIDVSKI RMRQVKSLMI FDR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.57
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [457-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AITLIHLHQY DRAAEDILSL LDISDWSHAF YTYFAGCCYL ENWRMCEMGL MKSDKKDEYQ  60
   61 KKAEELIFTS VNLLGKKTFK SKNLPLDRFI LRKVEQFKAK KEELGVENPL DGIATSPVHE 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.57
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [577-725]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAYFYNGYNR MSEEHLELTK KMLTEYRNPA IEALDSDQEL IKDLLVSLTL RRLGHIQEGC  60
   61 DILDEKVLPK FFSIQNGKVK YIKKTEDPWA YPTALYERAL FTWKLEGMDG LPESKEWLLR 120
  121 AQGYADDYEL STRVGMKIKA AIDRVDHSL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.57
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle