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View Structure Prediction Details

Protein: YKR018C
Organism: Saccharomyces cerevisiae
Length: 725 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKR018C.

Description E-value Query
Range
Subject
Range
YKR18_YEAST - Mitochondrial outer membrane protein YKR018C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c...
YKR018C - Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to th...
0.0 [1..725] [1..725]
TT39B_MACFA - Tetratricopeptide repeat protein 39B OS=Macaca fascicularis GN=TTC39B PE=2 SV=1
0.0 [123..718] [114..623]
gi|2865252 - gi|2865252|gb|AAC39582.1| unknown [Homo sapiens]
0.0 [119..725] [45..561]
SPAC11E3.14 - conserved protein
YDYE_SCHPO - Uncharacterized protein C11E3.14 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC11E3....
0.0 [118..723] [54..586]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-99 [323..707] [1..346]

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Predicted Domain #1
Region A:
Residues: [1-183]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKVFGFGAK EEIPELSQEE KTKAILKQAH DFEQALRAMD YVLDDNADEG LALLDESDAK  60
   61 EASDQTINAL ARGVIEFLEA TLGFEAEEMK KASATLAKAE ALSLKSRERA QKIGLKSSSL 120
  121 YPPGTVYAVT YTESCLLHAL LMIFSESMME AAKAILKLRK SYYMLQEILE TIKAANKAKK 180
  181 LKI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [184-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSGSEDKEST PATFITGGDA FNSVDIPYEL TPEEQKDKDL LQFAEQIHSM RTERLSGAHI  60
   61 GNSPAINRLR GELGLQAMED LPEEEITDHK VLSDDIDLSQ ATIDEFVHSG VNLCFGILQV 120
  121 VISLLPPAIG AVLSVVGFRG SREEGLRLVW KATKQRNVHG CIGLLALMFY YDGPFQFTDD 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [364-456]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFDIPAAVKD SSNSEDSEDE EMDGPTLLHP GKILEDALLQ SRALFPNSAL WLLNEARMLS  60
   61 GKGRLEEAVA LMDSIDVSKI RMRQVKSLMI FDR

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.57
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [457-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AITLIHLHQY DRAAEDILSL LDISDWSHAF YTYFAGCCYL ENWRMCEMGL MKSDKKDEYQ  60
   61 KKAEELIFTS VNLLGKKTFK SKNLPLDRFI LRKVEQFKAK KEELGVENPL DGIATSPVHE 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.57
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [577-725]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAYFYNGYNR MSEEHLELTK KMLTEYRNPA IEALDSDQEL IKDLLVSLTL RRLGHIQEGC  60
   61 DILDEKVLPK FFSIQNGKVK YIKKTEDPWA YPTALYERAL FTWKLEGMDG LPESKEWLLR 120
  121 AQGYADDYEL STRVGMKIKA AIDRVDHSL

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 10.57
Match: 1hz4A
Description: Transcription factor MalT domain III
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle