YRC Public Data Repository - Protein Structure Prediction

Protein:	YRA2
Organism:	Saccharomyces cerevisiae
Length:	203 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YRA2.

Description	E-value	Query Range	Subject Range
PABP1_BOVIN - Polyadenylate-binding protein 1 OS=Bos taurus GN=PABPC1 PE=2 SV=1 gi\|109087089 - gi\|109087089\|ref\|XP_001098239.1\| PREDICTED: poly(A) binding protein, cytoplasmic 1 isoform 2 [Macaca... gi\|123993665, gi... - gi\|168278070\|dbj\|BAG11013.1\| polyadenylate-binding protein 1 [synthetic construct], gi\|123999981\|gb\|... gi\|194036975 - gi\|194036975\|ref\|XP_001927782.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-bind... PABPC1 - poly(A) binding protein, cytoplasmic 1 gi\|73974130, gi\|... - gi\|73974178\|ref\|XP_857695.1\| PREDICTED: similar to Polyadenylate-binding protein 1 (Poly(A)-binding ...	1.0E-51	[12..183]	[137..307]
PABP1_MOUSE - Polyadenylate-binding protein 1 OS=Mus musculus GN=Pabpc1 PE=1 SV=2	1.0E-51	[12..183]	[137..307]
PABP1_RAT - Polyadenylate-binding protein 1 OS=Rattus norvegicus GN=Pabpc1 PE=1 SV=1	1.0E-51	[12..183]	[137..307]
gi\|13540314 - gi\|13540314\|gb\|AAK29408.1\|AF338225_1 embryonic poly(A) binding protein [Xenopus laevis]	1.0E-49	[12..184]	[137..308]

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Predicted Domain #1

Region A:
Residues: [1-203]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKAFDEIIG NSHTDSSSNH KVTRYRRRDL RNELGPRLGF APSDAASRSK DRLYREREEP  60
   61 PLPKRIRISK IPLDVSDYTL DDMIKEFGSP IFSKIFDNKE DRTCIYEFED PEVLEKIVER 120
  121 YNGHELHNAK IEVEIYQPQR KHSRMNAHNR RKQTAQEHGR GRPGSHYRQK PNRVSKKNKG 180
  181 REKNNTPTSV EALDAELDAY MKG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.09691
Match:	1cvjA_
Description:	Poly(A)-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleic acid binding	3.30589046985932	bayes_pls_golite062009
binding	3.05116833253954	bayes_pls_golite062009
RNA binding	2.47430823231895	bayes_pls_golite062009
protein binding	1.52056358240529	bayes_pls_golite062009
mRNA binding	1.30169099150772	bayes_pls_golite062009
DNA binding	0.202814601806347	bayes_pls_golite062009
poly-purine tract binding	0.15653271757169	bayes_pls_golite062009
transcription regulator activity	0.0111161191366809	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: