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View Structure Prediction Details

Protein: DOA1
Organism: Saccharomyces cerevisiae
Length: 715 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DOA1.

Description E-value Query
Range
Subject
Range
DOA1 - WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, pl...
DOA1_YEAST - Protein DOA1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=DOA1 PE=1 SV=1
gi|151941451 - gi|151941451|gb|EDN59815.1| conserved protein [Saccharomyces cerevisiae YJM789]
0.0 [1..715] [1..715]
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [2..532] [979..1495]
gi|17225210 - gi|17225210|gb|AAL37301.1|AF323585_1 beta transducin-like protein HET-D2Y [Podospora anserina]
0.0 [5..508] [823..1314]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [3..699] [8..774]
gi|7023020 - gi|7023020|dbj|BAA91803.1| unnamed protein product [Homo sapiens]
0.0 [3..699] [8..774]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYQLSATLK GHDQDVRDVV AVDDSKVASV SRDGTVRLWS KDDQWLGTVV YTGQGFLNSV  60
   61 CYDSEKELLL FGGKDTMING VPLFATSGE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 149.626727
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [90-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPLYTLIGHQ GNVCSLSFQD GVVISGSWDK TAKVWKEGSL VYNLQAHNAS VWDAKVVSFS  60
   61 ENKFLTASAD KTIKLWQNDK VIKTFSGIHN DVVRHLAVVD DGHFISCSND GLIKLVDMHT 120
  121 GDVLRTYEGH ESFVYCIKLL PNGDIVSCGE DRTVRIWSKE NGSLKQVITL PAISIWSVDC 180
  181 MSNGDIIVGS SDNLVRIFSQ EKSRWASEDE INELSTQVEK STISSKTIEF DESKLSPYEI 240
  241 LQSPGRKEGQ IVVVKSPQGT IEAHQFSNSS WKKVGDVVGA GATGNDKKIE FEGKTYDYVF 300
  301 DVDI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 58.190949
Match: 1gxrA_
Description: Groucho/tle1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [394-491]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDGKPPLKLP INVSDNPYTA ADNFLARYEL PMSYRDQVVQ FILKNTNGIS LDQPNDNASS  60
   61 SAVSPSKTSV MKVLPVKQYL IMENYNPDTI FNGIVKIN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.0
Match: 1k8kC_
Description: Arp2/3 complex 41 kDa subunit ARPC1
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [492-715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNEKTFDDEI LAQIGGALHD IDESWELLLS FANTIRSNWE IKTPAYDIVR LIVKKLPYSS  60
   61 DIKDYIEEGL GNKNITLTML TVRILVNCFN NENWGVKLLE SNQVYKSIFE TIDTEFSQAS 120
  121 AKQSQNLAIA VSTLIFNYSA LVTKGNSDLE LLPIVADAIN TKYGPLEEYQ ECEEAAYRLT 180
  181 VAYGNLATVE PTLRQFANSV TWLANIKRSY GNVPRFKDIF DDLS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [515-715]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SWELLLSFAN TIRSNWEIKT PAYDIVRLIV KKLPYSSDIK DYIEEGLGNK NITLTMLTVR  60
   61 ILVNCFNNEN WGVKLLESNQ VYKSIFETID TEFSQASAKQ SQNLAIAVST LIFNYSALVT 120
  121 KGNSDLELLP IVADAINTKY GPLEEYQECE EAAYRLTVAY GNLATVEPTL RQFANSVTWL 180
  181 ANIKRSYGNV PRFKDIFDDL S

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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