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View Structure Prediction Details

Protein: UBA1
Organism: Saccharomyces cerevisiae
Length: 1024 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBA1.

Description E-value Query
Range
Subject
Range
gi|19699087, gi|... - gi|30102506|gb|AAP21171.1| At2g30110/T27E13.15 [Arabidopsis thaliana], gi|19699087|gb|AAL90910.1| At...
0.0 [7..1023] [66..1078]
gi|100841 - gi|100841|pir||A38373 ubiquitin-protein ligase (EC 6.3.2.19) E1 - wheat
UBE11_WHEAT - Ubiquitin-activating enzyme E1 1 OS=Triticum aestivum GN=UBA1 PE=1 SV=1
0.0 [12..1023] [41..1049]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..1023] [59..1078]
UBA1_SCHPO - Ubiquitin-activating enzyme E1 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=ptr3 PE=1...
ptr3 - ubiquitin activating enzyme (E1)
0.0 [3..1024] [2..1012]
gi|6002801 - gi|6002801|gb|AAF00149.1|AF150963_1 ubiquitin-activating enzyme E1 [Mus musculus]
0.0 [4..1020] [39..1053]
gi|220956874, gi... - gi|220956874|gb|ACL90980.1| Uba1-PA [synthetic construct], gi|220947422|gb|ACL86254.1| Uba1-PA [synt...
Uba1-PA - The gene Ubiquitin activating enzyme 1 is referred to in FlyBase by the symbol Dmel\Uba1 (CG1782, FB...
0.0 [2..1020] [181..1186]

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Predicted Domain #1
Region A:
Residues: [1-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNNSGLSA AGEIDESLYS RQLYVLGKEA MLKMQTSNVL ILGLKGLGVE IAKNVVLAGV  60
   61 KSMTVFDPEP VQLADLSTQF FLTEKDIGQK RGDVTRAKLA ELNAYVPVNV LDSLDDVTQL 120
  121 SQFQVVVATD TVSLEDKVKI NEFCHSSGIR FISSETRGLF GNTFVDLGDE FTVLDPTGEE 180
  181 PRTGMVSDIE PDGTVTMLDD NRHGLEDGNF VRFSEVEGLD KLNDGTLFKV EVLGPFAFRI 240
  241 GSVKEYGEYK KGGIFTEVKV PRKISFKSLK QQLSNPEFVF SDFAKFDRAA QLHLGFQALH 300
  301 QFAVRH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 176.529817
Match: 1jw9B_
Description: Molybdenum cofactor biosynthesis protein MoeB
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [307-408]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGELPRTMND EDANELIKLV TDLSVQQPEV LGEGVDVNED LIKELSYQAR GDIPGVVAFF  60
   61 GGLVAQEVLK ACSGKFTPLK QFMYFDSLES LPDPKNFPRN EK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [409-620]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTQPVNSRYD NQIAVFGLDF QKKIANSKVF LVGSGAIGCE MLKNWALLGL GSGSDGYIVV  60
   61 TDNDSIEKSN LNRQFLFRPK DVGKNKSEVA AEAVCAMNPD LKGKINAKID KVGPETEEIF 120
  121 NDSFWESLDF VTNALDNVDA RTYVDRRCVF YRKPLLESGT LGTKGNTQVI IPRLTESYSS 180
  181 SRDPPEKSIP LCTLRSFPNK IDHTIAWAKS LF

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.43
Match: 1eq2A
Description: ADP-L-glycero-D-mannoheptose 6-epimerase
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [621-750]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QGYFTDSAEN VNMYLTQPNF VEQTLKQSGD VKGVLESISD SLSSKPHNFE DCIKWARLEF  60
   61 EKKFNHDIKQ LLFNFPKDAK TSNGEPFWSG AKRAPTPLEF DIYNNDHFHF VVAGASLRAY 120
  121 NYGIKSDDSN 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [751-813]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKPNVDEYKS VIDHMIIPEF TPNANLKIQV NDDDPDPNAN AANGSDEIDQ LVSSLPDPST  60
   61 LAG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [814-1024]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKLEPVDFEK DDDTNHHIEF ITACSNCRAQ NYFIETADRQ KTKFIAGRII PAIATTTSLV  60
   61 TGLVNLELYK LIDNKTDIEQ YKNGFVNLAL PFFGFSEPIA SPKGEYNNKK YDKIWDRFDI 120
  121 KGDIKLSDLI EHFEKDEGLE ITMLSYGVSL LYASFFPPKK LKERLNLPIT QLVKLVTKKD 180
  181 IPAHVSTMIL EICADDKEGE DVEVPFITIH L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle