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View Structure Prediction Details

Protein: MNN4
Organism: Saccharomyces cerevisiae
Length: 1178 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNN4.

Description E-value Query
Range
Subject
Range
gi|2980815 - gi|2980815|emb|CAA82044.1| MNN4 [Saccharomyces cerevisiae]
541.0 [0..1] [639..1]
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
495.0 [0..162] [1177..1865]
gi|28564137 - gi|28564137|gb|AAO32447.1| MNN4 [Saccharomyces bayanus]
458.0 [0..1] [744..1]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
384.0 [0..202] [1178..937]
MYH1_BOVIN - Myosin-1 OS=Bos taurus GN=MYH1 PE=2 SV=2
384.0 [0..202] [1178..938]
gi|50757621 - gi|50757621|ref|XP_415581.1| PREDICTED: similar to fast myosin heavy chain isoform 3 [Gallus gallus]
382.0 [0..202] [1178..1040]

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Predicted Domain #1
Region A:
Residues: [1-164]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQRISSKLH RRFLSGLLRV KHYPLRRILL PLILLQIIII TFIWSNSPQR NGLGRDADYL  60
   61 LPNYNELDSD DDSWYSILTS SFKNDRKIQF AKTLYENLKF GTNPKWVNEY TLQNDLLSVK 120
  121 MGPRKGSKLE SVDELKFYDF DPRLTWSVVL NHLQNNDADQ PEKL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [165-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PFSWYDWTTF HELNKLISID KTVLPCNFLF QSAFDKESLE AIETELGEPL FLYERPKYAQ  60
   61 KLWYKAARNQ DRIKDSKELK KHCSKLFTPD GHG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [258-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPKGLRFNTQ FQIKELYDKV RPEVYQLQAR NYILTTQSHP LSISIIESDN STYQVPLQTE  60
   61 KSKNLVQSGL LQEYINDNIN STNKRKKNKQ DVEFNHNRLF QEFVNNDQVN SLYKLEIEET 120
  121 DKFTFDKDLV YLSPSDFKFD ASKKIEELEE QKKLYPDKFS AHNENYLNSL KNSVKTSPAL 180
  181 QRKFFYEAGA VKQYKGMGFH RDKRFFNVDT LINDKQEYQA RLNSMIRTFQ KFTKANGIIS 240
  241 WLSHGTLYGY LYNGMAFPWD NDFDLQMPIK HLQLLSQYFN QSLILEDPRQ GNGRYFLDVS 300
  301 DSLTVRINGN GKNNIDARFI DVDTGLYIDI TGLASTSAPS RDYLNSYIEE RLQEEHLDIN 360
  361 NIPESNGETA TLPDKVDDGL VNMATLNITE LRDYITSDEN KNHKRVPTDT DLKDLLKKEL 420
  421 EELPKSKTIE NK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [690-1122]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNPKQRYFLN EKLKLYNCRN NHFNSFEELS PLINTVFHGV PALIPHRHTY CLHNEYHVPD  60
   61 RYAFDAYKNT AYLPEFRFWF DYDGLKKCSN INSWYPNIPS INSWNPNLLK EISSTKFESK 120
  121 LFDSNKVSEY SFKNLSMDDV RLIYKNIPKA GFIEVFTNLY NSFNVTAYRQ KELEIQYCQN 180
  181 LTFIEKKKLL HQLRINVAPK LSSPAKDPFL FGYEKAMWKD LSKSMNQTTL DQVTKIVHEE 240
  241 YVGKIIDLSE SLKYRNFSLF NITFDETGTT LDDNTEDYTP ANTVEVNPVD FKSNLNFSSN 300
  301 SFLDLNSYGL DLFAPTLSDV NRKGIQMFDK DPIIVYEDYA YAKLLEERKR REKKKKEEEE 360
  361 KKKKEEEEKK KKEEEEKKKK EEEEKKKKEE EEKKKKEEEE KKKQEEEEKK KKEEEEKKKQ 420
  421 EEGEKMKNED EEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.39794
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [1123-1178]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKNEDEEKKK NEEEEKKKQE EKNKKNEDEE KKKQEEEEKK KNEEEEKKKQ EEGHSN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle