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View Structure Prediction Details

Protein: PTK1
Organism: Saccharomyces cerevisiae
Length: 399 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTK1.

Description E-value Query
Range
Subject
Range
gi|1183859 - gi|1183859|dbj|BAA09884.1| PTK1p [Saccharomyces cerevisiae]
3.0E-94 [1..388] [1..417]
CDPK2_ARATH - Calcium-dependent protein kinase 2 OS=Arabidopsis thaliana GN=CPK2 PE=1 SV=1
5.0E-87 [13..399] [17..398]
gi|2315983 - gi|2315983|gb|AAB70706.1| calmodulin-like domain protein kinase [Tortula ruralis]
2.0E-81 [99..399] [23..324]
gi|4336426 - gi|4336426|gb|AAD17800.1| Ca2+-dependent protein kinase [Mesembryanthemum crystallinum]
2.0E-80 [113..399] [6..298]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-80 [171..399] [1..238]
gi|14029712 - gi|14029712|gb|AAK52801.1|AF363784_1 calcium-dependent protein kinase CDPK1 [Lycopersicon esculentum...
5.0E-80 [128..399] [6..285]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVSHNHSTK ISQQPISSVS AFKFFGKKLL SSSHGNKLKK KASLPPDFHS TSTNDSESSS  60
   61 PKLPNSLKTS RRANSFAHTT NSKRSLSSAS TKILPPAGSS TSISRGNRHS STSRNLSNSK 120
  121 FSSERLVYNP YGVSTPSTSL SSVSTSMKKD PDLGFYLHD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [160-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDSKIRMLPI PIVDPNEYLP DEMKEASIQL SDNFVFDDEN KTIGWGGSCE VRKIRSKYRK  60
   61 KDVFALKKLN MIYNETPEKF YNAAPKEFI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [262-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFLLVKVPTT VYTTRGWGFV MEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 146.071898
Match: 1giiA_
Description: Cyclin-dependent PK, CDK2
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [249-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAKQLSHHVH ITN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [285-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLRDLFAMIQ KSGWRHVALA EKFCIFKQVA CGVKFCHDQG IAHRDLKPEN VLLSPDGVCK  60
   61 LTDFGISDWY HHGSTRPVQP CQEVRRDDRL AAVCSPGGHV LRLQEALRYG IATAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 146.071898
Match: 1giiA_
Description: Cyclin-dependent PK, CDK2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle