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View Structure Prediction Details

Protein: PTK1
Organism: Saccharomyces cerevisiae
Length: 399 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PTK1.

Description E-value Query
Range
Subject
Range
gi|1183859 - gi|1183859|dbj|BAA09884.1| PTK1p [Saccharomyces cerevisiae]
3.0E-94 [1..388] [1..417]
CDPK2_ARATH - Calcium-dependent protein kinase 2 OS=Arabidopsis thaliana GN=CPK2 PE=1 SV=1
5.0E-87 [13..399] [17..398]
gi|2315983 - gi|2315983|gb|AAB70706.1| calmodulin-like domain protein kinase [Tortula ruralis]
2.0E-81 [99..399] [23..324]
gi|4336426 - gi|4336426|gb|AAD17800.1| Ca2+-dependent protein kinase [Mesembryanthemum crystallinum]
2.0E-80 [113..399] [6..298]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
3.0E-80 [171..399] [1..238]
gi|14029712 - gi|14029712|gb|AAK52801.1|AF363784_1 calcium-dependent protein kinase CDPK1 [Lycopersicon esculentum...
5.0E-80 [128..399] [6..285]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVSHNHSTK ISQQPISSVS AFKFFGKKLL SSSHGNKLKK KASLPPDFHS TSTNDSESSS  60
   61 PKLPNSLKTS RRANSFAHTT NSKRSLSSAS TKILPPAGSS TSISRGNRHS STSRNLSNSK 120
  121 FSSERLVYNP YGVSTPSTSL SSVSTSMKKD PDLGFYLHD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [160-248]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GDSKIRMLPI PIVDPNEYLP DEMKEASIQL SDNFVFDDEN KTIGWGGSCE VRKIRSKYRK  60
   61 KDVFALKKLN MIYNETPEKF YNAAPKEFI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [262-284]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFLLVKVPTT VYTTRGWGFV MEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 146.071898
Match: 1giiA_
Description: Cyclin-dependent PK, CDK2
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [249-261]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAKQLSHHVH ITN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [285-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLRDLFAMIQ KSGWRHVALA EKFCIFKQVA CGVKFCHDQG IAHRDLKPEN VLLSPDGVCK  60
   61 LTDFGISDWY HHGSTRPVQP CQEVRRDDRL AAVCSPGGHV LRLQEALRYG IATAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 146.071898
Match: 1giiA_
Description: Cyclin-dependent PK, CDK2
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle