YRC Public Data Repository - Protein Structure Prediction

Protein:	SDS22
Organism:	Saccharomyces cerevisiae
Length:	338 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SDS22.

Description	E-value	Query Range	Subject Range
gi\|12054894 - gi\|12054894\|emb\|CAC20842.1\| receptor protein kinase [Pinus sylvestris]	2.0E-72	[1..334]	[300..643]
gi\|18390097 - gi\|18390097\|gb\|AAL68842.1\|AF466199_1 putative receptor protein kinase [Sorghum bicolor]	2.0E-69	[1..331]	[68..407]
gi\|37535238, gi\|... - gi\|37535238\|ref\|NP_921921.1\| putative protein kinase [Oryza sativa (japonica cultivar-group)], gb\|AA...	2.0E-68	[1..330]	[195..536]
BRL2_ARATH - Serine/threonine-protein kinase BRI1-like 2 OS=Arabidopsis thaliana GN=BRL2 PE=1 SV=1	7.0E-68	[1..330]	[159..505]
gi\|20042880, gi\|... - gi\|20042880\|gb\|AAM08708.1\| Putative protein kinase [Oryza sativa (japonica cultivar-group)], gi\|1692... gi\|20042880, gi\|... - gi\|37530616\|ref\|NP_919610.1\| putative protein kinase [Oryza sativa (japonica cultivar-group)], gi\|31...	3.0E-66	[1..338]	[285..628]
gi\|7144483 - gi\|7144483\|gb\|AAF26357.2\| Scribble [Drosophila melanogaster]	3.0E-66	[1..336]	[67..399]
gi\|3894391 - gi\|3894391\|gb\|AAC78595.1\| Hcr2-5B [Lycopersicon esculentum]	5.0E-66	[1..330]	[102..441]
gi\|3894387 - gi\|3894387\|gb\|AAC78593.1\| Hcr2-0B [Lycopersicon esculentum]	7.0E-66	[1..330]	[102..441]

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Predicted Domain #1

Region A:
Residues: [1-111]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKNSVNKDS EEKDERHKIE VVDDTNPDFI TADSELTQDL PDDVEVIDLV HLKIKSLEDL  60
   61 NLYRFKNLKQ LCLRQNLIES ISEVEVLPHD KIVDLDFYDN KIKHISSNVN K

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.154902
Match:	1k5dC_
Description:	Rna1p (RanGAP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.87302803330255	bayes_pls_golite062009
receptor activity	0.823142813332745	bayes_pls_golite062009
protein binding	0.646159692466759	bayes_pls_golite062009
transmembrane receptor activity	0.569410390698942	bayes_pls_golite062009
signal transducer activity	0.405945668463821	bayes_pls_golite062009
molecular transducer activity	0.405945668463821	bayes_pls_golite062009
phosphatase regulator activity	0.276491806064691	bayes_pls_golite062009
nucleic acid binding	0.246718758617065	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [112-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LTKLTSLDLS FNKIKHIKNL ENLTDLENLY FVQNSISKIE NLSTLKSLKN LELGGNKVHS  60
   61 IEPDSFEGLS NLEEIWLGKN SIPRLINLHP LKNLKILSIQ SNKLKKIENL EELTNLEELY 120
  121 LSHNFITKIE GLEKNLKLTT LDVTSNKITS LENLNHLSNL TDIWASFNKI DQSFESLGEN 180
  181 LSALSRLETI YLEGNPIQLE NKTSYRRKLT MNLPPSLQKI DATYIRG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	144.154902
Match:	1h6uA_
Description:	Internalin H
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: